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Query: WNT5A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WNT5A 0 -0.304

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WNT5A Ubiquitylation K268 -0.304 _VGDALK(gl)EK_

Background Information for WNT5A:


Pubmed-WNT5A »
Uniprot-WNT5A »
Biogrid-WNT5A »
ProteomicsDB-WNT5A »

Tumorportal-WNT5A »
COSMIC-WNT5A »
GenomeRNAi-WNT5A »
Genecards-WNT5A


Protein-protein Interactions for WNT5A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANTXR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPHA7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLA2G10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PROC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPRK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCTN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WNT5A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Wnt IPR005817 0


Protein complexes (CORUM database) featuring WNT5A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WNT5A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members Pathway Pathway_1105 REACTOME_GPCR_LIGAND_BINDING 0 2.35
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0005125 cytokine activity Database 1.06
Category members Pathway Pathway_1104 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS 0 0.93
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0005796 Golgi lumen Database 0.64
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0005578 proteinaceous extracellular matrix Database 0.53
Category members GO Category GO:0050679 positive regulation of epithelial cell proliferation Database 0.5
Category members GO Category GO:0045836 positive regulation of meiosis Database 0.48
Category members GO Category GO:0031012 extracellular matrix Database 0.45
Category members GO Category GO:0030324 lung development Database 0.39
Category members GO Category GO:0070245 positive regulation of thymocyte apoptotic process Database 0.37
Category members GO Category GO:0003344 pericardium morphogenesis Database 0.33
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0060638 mesenchymal-epithelial cell signaling Database 0.26
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0060686 negative regulation of prostatic bud formation Database 0.23
Category members GO Category GO:0001934 positive regulation of protein phosphorylation Database 0.22
Category members Pathway Pathway_142 PID_MYC_REPRESS_PATHWAY 0 0.21
Category members GO Category GO:0045766 positive regulation of angiogenesis Database 0.19
Category members GO Category GO:0050680 negative regulation of epithelial cell proliferation Database 0.19
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0045599 negative regulation of fat cell differentiation Database 0.13
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0005110 frizzled-2 binding Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0050718 positive regulation of interleukin-1 beta secretion Database 0.13
Category members GO Category GO:0071219 cellular response to molecule of bacterial origin Database 0.13
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0003323 type B pancreatic cell development Database 0.1
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members Pathway Pathway_417 PID_WNT_NONCANONICAL_PATHWAY 0 0.09
Category members GO Category GO:0001947 heart looping Database 0.08
Category members GO Category GO:0060324 face development Database 0.08
Category members GO Category GO:0007257 activation of JUN kinase activity Database 0.08
Category members GO Category GO:0032729 positive regulation of interferon-gamma production Database 0.08
Category members GO Category GO:0050729 positive regulation of inflammatory response Database 0.08
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0045080 positive regulation of chemokine biosynthetic process Database 0.06
Category members GO Category GO:0010976 positive regulation of neuron projection development Database 0.05
Category members GO Category GO:0048146 positive regulation of fibroblast proliferation Database 0.05
Category members GO Category GO:0034613 cellular protein localization Database 0.04
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0001667 ameboidal cell migration Database 0.04
Category members GO Category GO:0032755 positive regulation of interleukin-6 production Database 0.04
Category members Pathway Pathway_1151 KEGG_HEDGEHOG_SIGNALING_PATHWAY 0 0.04
Category members GO Category GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway Database 0.04
Category members GO Category GO:0071346 cellular response to interferon-gamma Database 0.04
Category members GO Category GO:0033138 positive regulation of peptidyl-serine phosphorylation Database 0.03
Category members GO Category GO:0021915 neural tube development Database 0.03
Category members GO Category GO:0060071 Wnt signaling pathway, planar cell polarity pathway Database 0.02
Category members GO Category GO:0007494 midgut development Database 0.01
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_1163 KEGG_BASAL_CELL_CARCINOMA 0 0
Category members Pathway Pathway_1277 PID_WNT_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_244 KEGG_MELANOGENESIS 0 0
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members Disease phenotype ROBINOW_SYNDROME_AUTOSOMAL_DOMINANT ROBINOW SYNDROME AUTOSOMAL DOMINANT Database 0
Category members GO Category GO:0000187 activation of MAPK activity Database 0
Category members GO Category GO:0001736 establishment of planar polarity Database 0
Category members GO Category GO:0001756 somitogenesis Database 0
Category members GO Category GO:0001837 epithelial to mesenchymal transition Database 0
Category members GO Category GO:0001843 neural tube closure Database 0
Category members GO Category GO:0001938 positive regulation of endothelial cell proliferation Database 0
Category members GO Category GO:0002009 morphogenesis of an epithelium Database 0
Category members GO Category GO:0002053 positive regulation of mesenchymal cell proliferation Database 0
Category members GO Category GO:0002088 lens development in camera-type eye Database 0
Category members GO Category GO:0002741 positive regulation of cytokine secretion involved in immune response Database 0
Category members GO Category GO:0003401 axis elongation Database 0
Category members GO Category GO:0003408 optic cup formation involved in camera-type eye development Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005109 frizzled binding Database 0
Category members GO Category GO:0005788 endoplasmic reticulum lumen Database 0
Category members GO Category GO:0007223 Wnt signaling pathway, calcium modulating pathway Database 0
Category members GO Category GO:0007254 JNK cascade Database 0
Category members GO Category GO:0007442 hindgut morphogenesis Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0008584 male gonad development Database 0
Category members GO Category GO:0008595 anterior/posterior axis specification, embryo Database 0
Category members GO Category GO:0009790 embryo development Database 0
Category members GO Category GO:0010033 response to organic substance Database 0
Category members GO Category GO:0010595 positive regulation of endothelial cell migration Database 0
Category members GO Category GO:0010800 positive regulation of peptidyl-threonine phosphorylation Database 0
Category members GO Category GO:0010820 positive regulation of T cell chemotaxis Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0030182 neuron differentiation Database 0
Category members GO Category GO:0030216 keratinocyte differentiation Database 0
Category members GO Category GO:0030326 embryonic limb morphogenesis Database 0
Category members GO Category GO:0030514 negative regulation of BMP signaling pathway Database 0
Category members GO Category GO:0030825 positive regulation of cGMP metabolic process Database 0
Category members GO Category GO:0032148 activation of protein kinase B activity Database 0
Category members GO Category GO:0035108 limb morphogenesis Database 0
Category members GO Category GO:0036342 post-anal tail morphogenesis Database 0
Category members GO Category GO:0038031 non-canonical Wnt signaling pathway via JNK cascade Database 0
Category members GO Category GO:0042060 wound healing Database 0
Category members GO Category GO:0042472 inner ear morphogenesis Database 0
Category members GO Category GO:0042733 embryonic digit morphogenesis Database 0
Category members GO Category GO:0043032 positive regulation of macrophage activation Database 0
Category members GO Category GO:0043507 positive regulation of JUN kinase activity Database 0
Category members GO Category GO:0045165 cell fate commitment Database 0
Category members GO Category GO:0045732 positive regulation of protein catabolic process Database 0
Category members GO Category GO:0045778 positive regulation of ossification Database 0
Category members GO Category GO:0046330 positive regulation of JNK cascade Database 0
Category members GO Category GO:0046546 development of primary male sexual characteristics Database 0
Category members GO Category GO:0048018 receptor agonist activity Database 0
Category members GO Category GO:0048546 digestive tract morphogenesis Database 0
Category members GO Category GO:0048706 embryonic skeletal system development Database 0
Category members GO Category GO:0048806 genitalia development Database 0
Category members GO Category GO:0048812 neuron projection morphogenesis Database 0
Category members GO Category GO:0048843 negative regulation of axon extension involved in axon guidance Database 0
Category members GO Category GO:0048850 hypophysis morphogenesis Database 0
Category members GO Category GO:0050919 negative chemotaxis Database 0
Category members GO Category GO:0051092 positive regulation of NF-kappaB transcription factor activity Database 0
Category members GO Category GO:0051216 cartilage development Database 0
Category members GO Category GO:0051964 negative regulation of synapse assembly Database 0
Category members GO Category GO:0060026 convergent extension Database 0
Category members GO Category GO:0060029 convergent extension involved in organogenesis Database 0
Category members GO Category GO:0060065 uterus development Database 0
Category members GO Category GO:0060068 vagina development Database 0
Category members GO Category GO:0060070 canonical Wnt signaling pathway Database 0
Category members GO Category GO:0060157 urinary bladder development Database 0
Category members GO Category GO:0060340 positive regulation of type I interferon-mediated signaling pathway Database 0
Category members GO Category GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis Database 0
Category members GO Category GO:0060744 mammary gland branching involved in thelarche Database 0
Category members GO Category GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation Database 0
Category members GO Category GO:0060760 positive regulation of response to cytokine stimulus Database 0
Category members GO Category GO:0060762 regulation of branching involved in mammary gland duct morphogenesis Database 0
Category members GO Category GO:0060907 positive regulation of macrophage cytokine production Database 0
Category members GO Category GO:0061036 positive regulation of cartilage development Database 0
Category members GO Category GO:0071222 cellular response to lipopolysaccharide Database 0
Category members GO Category GO:0071277 cellular response to calcium ion Database 0
Category members GO Category GO:0071300 cellular response to retinoic acid Database 0
Category members GO Category GO:0071425 hematopoietic stem cell proliferation Database 0


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