RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
GSK3B	2	1.020	-0.870				-1.128	1.091
CAMK2G	2	-2.070	4.160
CAMK2G	2	-2.070	4.160
CAMK2G	2	-2.070	4.160		-0.654	0.073
CAMK2G	2	-2.070	4.160				0.559	1.698
CAMK2B	1	1.200	-0.790
CAMK2B	1	1.200	-0.790		-0.654	0.073
CAMK2B	1	1.200	-0.790	-0.619			0.544	0.125
CAMK2B	1	1.200	-0.790				0.559	1.698
GNAI3	1	0.750	-0.890
GNAI3	1	0.750	-0.890	0.217			-0.334	-0.374
GNAO1	1	1.200	-1.320
GNAO1	1	1.200	-1.320	0.217			-0.334	-0.374
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
ADCY3	1	-0.850	1.180
CALM2	1	-0.690	0.700		1.911
CALM2	1	-0.690	0.700				0.877	-4.680
TCF7L1	1	-2.040	2.970	-0.741
FZD7	1	2.260	-1.160
CALM3	1	-0.190	0.120		1.911
CALM3	1	-0.190	0.120				0.877	-4.680
MAP2K1	1	-1.590	2.780
CREB3L2	1	-2.290	4.300
CALM1	1	-0.440	0.360		1.911
CALM1	1	-0.440	0.360				0.877	-4.680
NRAS	1	1.810	-0.720				0.246	-0.346
DVL2	0	-0.050	0.580
CREBBP	0	0.840	-0.950				-3.889	-1.071
GNAI1	0	-0.580	0.990
GNAI2	0	0.190	-0.520
GNAL	0	1.660	-1.170
GNAS	0	0.840	-0.750
GNAT1	0	-0.110	-0.270
GNAT2	0	0.140	-0.880
GNAT3	0	1.110	-0.500
CAMK2A	0	-0.430	0.130		-0.654	0.073
CAMK2A	0	-0.430	0.130	-0.619			0.544	0.125
PRKACA	0	0.380	-0.680		-1.005	-0.697	0.234	0.487
TCF7	0	1.040	-0.330	-0.741
GNAS	0	0.840	-0.750
GNAS	0	0.840	-0.750
GNAS	0	0.840	-0.750	-0.166	-0.094	0.032	0.420	0.504
EP300	0	-1.210	1.320	-1.089			-1.694	-0.723
PLCB4	0	0.640	-0.400
MAPK3	0
CREB3	0	0.180	-0.820
WNT5A	0
CREB1	0	1.080	-0.800			-1.027
ADCY7	0
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
GNAI1	0	-0.580	0.990	0.116			-0.747
LEF1	0	-0.710	0.790	-0.741
PRKACB	0	1.740	-1.200		-1.064
PRKACB	0	1.740	-1.200		-1.005	-0.697	0.234	0.487
CREB3L4	0	0.100	-0.520
CAMK2D	0	-0.260	0.500		-0.654	0.073
CAMK2D	0	-0.260	0.500	-0.619			0.544	0.125
CAMK2D	0	-0.260	0.500
TCF7L2	0	-0.550	0.790	-0.741
PRKCA	0	0.750	-0.690				0.349	0.585
PRKCA	0	0.750	-0.690
GNAQ	0	0.140	-0.310				0.052	0.449
DVL3	0	0.890	-0.290
ADCY9	0	-0.910	0.930
FZD5	0	-0.880	0.520
PRKCB	0	0.260	-0.530
PRKCB	0	0.260	-0.530				0.349	0.585
CTNNB1	0	0.490	-0.230
CTNNB1	0	0.490	-0.230	-0.415			0.628	0.215
ADCY6	0	-0.720	0.740
HRAS	0	1.470	-0.520
CALML3	0	0.460	-0.670
CALML5	0	-0.980	1.530
PLCB1	0	-0.300	-0.220

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ADCY3	Ubiquitylation	K406	-0.885		_TK(gl)TGVDMR_
ADCY3	Ubiquitylation	K628		0.051	_YSVEK(gl)EK_
ADCY3	Ubiquitylation	K879	0.818	2.820	_IEVHDQK(gl)ER_
ADCY3	Ubiquitylation	K1047		-1.036	_IGMNK(gl)GGVLAGVIGAR_
ADCY6	Phosphorylation	S54	-1.434	-1.374	_DAEPPS(ph)PTPAGPPR_
ADCY6	Ubiquitylation	K80	0.473	0.937	_GK(gl)ELGLR_
ADCY6	Ubiquitylation	K568	1.007	0.799	_AMLAK(gl)LQR_
ADCY6	Phosphorylation	S576		-0.020	_ANS(ph)MEGLMPR_
ADCY7	Ubiquitylation	K477		0.660	_GDAALK(gl)MR_
ADCY9	Ubiquitylation	K35	0.400		_INPK(gl)QLSSNSHPK_
ADCY9	Ubiquitylation	K564	0.874	0.253	_LGQSVVADQLK(gl)GLK_
ADCY9	Ubiquitylation	K622	0.176	0.287	_GQGTASSGNVSDLAQTVK(gl)TFDNLK_
ADCY9	Ubiquitylation	K628	0.266		_TFDNLK(gl)TCPSCGITFAPK_
ADCY9	Ubiquitylation	K699		1.085	_LTNSQTSLCEILQEK(gl)GR_
ADCY9	Ubiquitylation	K1218	1.351	1.067	_VLSK(gl)MGYDFDYR_
CALM1	Ubiquitylation	K78	0.061		_DGDGTITTK(gl)ELGTVMR_
CALM1	Ubiquitylation	K142		0.922	_VFDK(gl)DGNGYISAAELR_
CALM2	Ubiquitylation	K78	0.061		_DGDGTITTK(gl)ELGTVMR_
CALM2	Ubiquitylation	K142		0.922	_VFDK(gl)DGNGYISAAELR_
CALM3	Ubiquitylation	K78	0.061		_DGDGTITTK(gl)ELGTVMR_
CALM3	Ubiquitylation	K142		0.922	_VFDK(gl)DGNGYISAAELR_
CAMK2A	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2B	Ubiquitylation	K147		-1.064	_DLKPENLLLASK(gl)CK_
CAMK2B	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2D	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2D	Phosphorylation	S330	0.412	0.370	_KPDGVKES(ph)TESSNTTIEDEDVK_
CAMK2D	Phosphorylation	T331		-0.174	_KPDGVKES(ph)TESSNTTIEDEDVK_
CAMK2D	Phosphorylation	T336	0.615	0.376	_ESTESSNT(ph)TIEDEDVK_
CAMK2D	Phosphorylation	T337	0.450		_ESTESSNTT(ph)IEDEDVK_
CAMK2G	Ubiquitylation	K147		-1.064	_DLKPENLLLASK(gl)CK_
CAMK2G	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2G	Phosphorylation	S365		0.765	_GSTES(ph)CNTTTEDEDLK_
CREB1	Phosphorylation	S271	-0.979	-1.450	_TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1	Ubiquitylation	K333	1.343		_ALK(gl)DLYCHK_
CREB3	Ubiquitylation	K176		-0.114	_TEEQILK(gl)R_
CREB3L2	Ubiquitylation	K364		-0.016	_LQTLVMGK(gl)VSR_
CREB3L4	Ubiquitylation	K51		0.433	_LQEQGLQGWK(gl)SGGDR_
CREB3L4	Ubiquitylation	K261		0.658	_VAACSAQNQELQK(gl)K_
CREBBP	Phosphorylation	S2093	0.037	0.097	_SIS(ph)PSALQDLLR_
CTNNB1	Ubiquitylation	K158		-1.265	_AIPELTK(gl)LLNDEDQVVVNK_
CTNNB1	Ubiquitylation	K180	-0.546	-0.636	_AAVM(ox)VHQLSK(gl)K_
CTNNB1	Ubiquitylation	K181	-0.717	-0.729	_AAVMVHQLSKK(gl)_
CTNNB1	Phosphorylation	S191	-0.024	0.129	_S(ph)PQMVSAIVR_
CTNNB1	Ubiquitylation	K435		-0.350	_NK(gl)MM(ox)VCQVGGIEALVR_
CTNNB1	Ubiquitylation	K496		-1.262	_LHYGLPVVVK(gl)_
CTNNB1	Phosphorylation	S552	1.233	1.224	_RTS(ph)MGGTQQQFVEGVR_
CTNNB1	Phosphorylation	T556	1.275	0.995	_RTSM(ox)GGT(ph)QQQFVEGVR_
CTNNB1	Ubiquitylation	K671	-0.941	-0.934	_MSEDKPQDYK(gl)K_
DVL2	Ubiquitylation	K343	0.846	-1.366	_DIVHK(gl)PGPIVLTVAK_
DVL3	Phosphorylation	S112	-0.787		_TGGIGDS(ph)RPPSFHPHAGGGSQENLDNDTETDSLVSAQR_
DVL3	Phosphorylation	S125	-0.854	-0.531	_TGGIGDSRPPSFHPHAGGGS(ph)QENLDNDTETDSLVSAQR_
EP300	Phosphorylation	S1038	-0.672	-0.349	_TEIKEEEDQPSTSATQSS(ph)PAPGQSK_
EP300	Phosphorylation	S1726	0.994	0.627	_LGLGLDDESNNQQAAATQS(ph)PGDSRR_
EP300	Phosphorylation	S2328	-1.092	0.725	_PQSQPPHSSPS(ph)PR_
FZD5	Ubiquitylation	K209		-0.563	_ESHPLYNK(gl)VR_
FZD7	Ubiquitylation	K569	0.551	0.319	_LSHSSK(gl)GETAV_
GNAI1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI1	Ubiquitylation	K92	0.873	0.567	_LK(gl)IDFGDSAR_
GNAI2	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI3	Ubiquitylation	K29	0.529	-0.094	_NLREDGEK(gl)AAK_
GNAI3	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI3	Ubiquitylation	K92	1.569		_LK(gl)IDFGEAAR_
GNAI3	Ubiquitylation	K349	-0.221	-0.339	_NNLK(gl)ECGLY_
GNAL	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAO1	Ubiquitylation	K29	0.529	-0.094	_NLREDGEK(gl)AAK_
GNAO1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAO1	Ubiquitylation	K92	1.569		_LK(gl)IDFGEAAR_
GNAO1	Ubiquitylation	K349	-0.221	-0.339	_NNLK(gl)ECGLY_
GNAQ	Ubiquitylation	K16	0.245		_TLESIMACCLSEEAK(gl)EAR_
GNAQ	Ubiquitylation	K102	-0.299		_IPYK(gl)YEHNK_
GNAS	Ubiquitylation	K8	0.430	0.328	_GCLGNSK(gl)TEDQRNEEK(gl)AQR_
GNAS	Ubiquitylation	K17	-0.011		_GCLGNSK(gl)TEDQRNEEK(gl)AQR_
GNAS	Ubiquitylation	K32	0.249	-0.446	_QLQK(gl)DKQVYR_
GNAS	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAS	Ubiquitylation	K58	-1.182	0.161	_STIVK(gl)QM(ox)R_
GNAS	Ubiquitylation	K92	-1.333	-0.290	_ATK(gl)VQDIKNNLK_
GNAS	Ubiquitylation	K97		0.076	_VQDIK(gl)NNLK_
GNAS	Ubiquitylation	K167	-1.721		_LHALK(gl)LR_
GNAS	Ubiquitylation	K301	-0.955	-0.198	_QDLLAEK(gl)VLAGK_
GNAS	Ubiquitylation	K308		-0.472	_SK(gl)IEDYFPEFAR_
GNAT1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT2	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT3	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GSK3B	Phosphorylation	S9	-0.483	0.010	_TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B	Ubiquitylation	K85		-0.204	_LCDSGELVAIK(gl)K_
GSK3B	Ubiquitylation	K86		-0.204	_LCDSGELVAIK(gl)K_
GSK3B	Phosphorylation	S215	0.296	0.477	_GEPNVS(ph)YICSR_
GSK3B	Phosphorylation	Y216	0.356	0.376	_GEPNVSY(ph)ICSR_
GSK3B	Phosphorylation	T390	2.800	2.527	_IQAAAST(ph)PTNATAASDANTGDR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
LEF1	Ubiquitylation	K88	-0.867	-0.222	_ESLEEAAK(gl)R_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PLCB1	Phosphorylation	S1199	-0.494		_TPS(ph)SEELGGDIPGKEFDTPL_
PLCB1	Phosphorylation	S1200		-0.483	_TPSS(ph)EELGGDIPGKEFDTPL_
PLCB4	Ubiquitylation	K284	1.083	0.038	_K(gl)GLISSDGFCR_
PRKACA	Ubiquitylation	K30	-0.143		_AKEDFLKK(gl)_
PRKACA	Ubiquitylation	K93	0.839	0.714	_QIEHTLNEK(gl)R_
PRKACB	Ubiquitylation	K30	-0.143		_AKEDFLKK(gl)_
PRKACB	Ubiquitylation	K93	0.839	0.714	_QIEHTLNEK(gl)R_
PRKACB	Phosphorylation	T243		-0.835	_T(ph)WTLCGTPEYLAPEIILSK_
PRKACB	Phosphorylation	T245	-0.116	-0.102	_TWT(ph)LCGTPEYLAPEIILSK_
PRKCA	Phosphorylation	S10	-0.650	0.036	_(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA	Phosphorylation	S13	-1.038	0.335	_(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA	Phosphorylation	S226	0.693	0.415	_STLNPQWNES(ph)FTFK_
PRKCA	Ubiquitylation	K316	-0.522	-0.535	_LGPAGNK(gl)VISPSEDR_
PRKCB	Phosphorylation	S10	-0.650	0.036	_(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCB	Phosphorylation	S13	-1.038	0.335	_(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCB	Phosphorylation	S226	0.693	0.415	_STLNPQWNES(ph)FTFK_
PRKCB	Ubiquitylation	K315	0.213	0.518	_ISQGTK(gl)VPEEK_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
TCF7	Ubiquitylation	K88	-0.867	-0.222	_ESLEEAAK(gl)R_
TCF7L1	Ubiquitylation	K88	-0.867	-0.222	_ESLEEAAK(gl)R_
TCF7L2	Ubiquitylation	K88	-0.867	-0.222	_ESLEEAAK(gl)R_
WNT5A	Ubiquitylation	K268		-0.304	_VGDALK(gl)EK_