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Query: PLCB4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PLCB4 0 1.121 0.640 -0.400

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PLCB4 Ubiquitylation K284 1.083 0.038 _K(gl)GLISSDGFCR_

Background Information for PLCB4:


Pubmed-PLCB4 »
Uniprot-PLCB4 »
Biogrid-PLCB4 »
ProteomicsDB-PLCB4 »

Tumorportal-PLCB4 »
COSMIC-PLCB4 »
GenomeRNAi-PLCB4 »
Genecards-PLCB4


Protein-protein Interactions for PLCB4
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in PLCB4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PI-PLC_fam IPR001192 0.03
Category members PLipase_C_Pinositol-sp_Y IPR001711 0.03
Category members PLipase_C_EF-hand-like IPR015359 0.03
Category members C2_dom IPR000008 0
Category members PLipase_C_PInositol-sp_X_dom IPR000909 0
Category members PLC-beta_CS IPR009535 0
Category members PLC-beta IPR016280 0
Category members PLC-like_Pdiesterase_TIM-brl IPR017946 0


Protein complexes (CORUM database) featuring PLCB4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PLCB4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_286 KEGG_LONG_TERM_DEPRESSION 0 0.31
Category members Pathway Pathway_260 REACTOME_OPIOID_SIGNALLING 0 0.28
Category members Pathway Pathway_106 KEGG_INOSITOL_PHOSPHATE_METABOLISM 0 0.28
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0004629 phospholipase C activity Database 0.23
Category members Pathway Pathway_232 KEGG_LONG_TERM_POTENTIATION 0 0.21
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members Pathway Pathway_213 KEGG_GAP_JUNCTION 0 0.11
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members GO Category GO:0005790 smooth endoplasmic reticulum Database 0.08
Category members Pathway Pathway_518 ST_G_ALPHA_I_PATHWAY 0 0.05
Category members Pathway Pathway_486 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 0 0.04
Category members Pathway Pathway_160 KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION 0 0.01
Category members Pathway Pathway_227 REACTOME_PLC_BETA_MEDIATED_EVENTS 0 0
Category members Pathway Pathway_244 KEGG_MELANOGENESIS 0 0
Category members Pathway Pathway_252 KEGG_CHEMOKINE_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_257 KEGG_GNRH_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_29 KEGG_ALZHEIMERS_DISEASE 0 0
Category members Pathway Pathway_487 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 0 0
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members Disease phenotype AURICULOCONDYLAR_SYNDROME AURICULOCONDYLAR SYNDROME Database 0
Category members GO Category GO:0004435 phosphatidylinositol phospholipase C activity Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007602 phototransduction Database 0
Category members GO Category GO:0008081 phosphoric diester hydrolase activity Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0
Category members GO Category GO:0016042 lipid catabolic process Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0043647 inositol phosphate metabolic process Database 0


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