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VennView



This section allows to create a Venndiagram like analysis of the data. Select a data ranges from the various screens you are interested in and hit the 'Show results matching the above criteria' button

Select a datarange of interest for each screen using the sliders below. For the RNAi low transcription screen we consider all genes above a z-score of 2.5 as scored, for the RNAi high screen all genes with a z-score of 2 or bigger. For proteomic experiments, we consider a protein recruited to CSB, RNAPII or chromatin if it features a z-score of 1.5 or bigger. A protein is dissociationg from CSB, RNAPII or chromatin if it features with a z-score of -1.5 or smaller in an experiment. A phosphorylation event is considered to increase upon UV-treatment if it has a z-score of 1.5 or higher. If the post-translational modification z-score is below -1.5, the PTM is considered to decrease upon UV-irradiation.

Currently all datapoints are selected. Narrow down the range by moving the sliders. Queries for individual experiments are linked by 'AND'. E.g. selecting the 'scored' ranges of two individual experiments will give you the genes that have scored in BOTH experiments. All other sliders should in this instance be set from minimum to maximum.

Display genes that have scored in the following screens:


Selection
Screen
Description
z-score range considered as 'scored' in response to UV in this screen
RNAi high transcribers
More transcription after UV-treatment and gene specific siRNA knockdown (comparison: UV-treated control siRNA knockdown)
2 to 6.2 (maximum)
RNAi low transcribers
Less transcription after UV-treatment and gene specific siRNA knockdown (comparison: UV-treated control siRNA knockdown)
2.5 to 6.2 (maximum)
RNAPII-IP (MG132) from chromatin SILAC -/+ UV
Proteins, that are recruited to RNAPII in a UV-dependent fashion in the presence of the proteasome inhibitor MG132
1.5 to 9.4 (maximum)
CSB-IP from chromatin SILAC -/+ UV
Proteins, that are recruited to CSB in a UV-dependent fashion
1.5 to 4.7 (maximum)
CSB-IP (MG132) from chromatin SILAC -/+ UV
Proteins, that are recruited to CSB in a UV-dependent fashion in the presence of the proteasome inhibitor MG132
1.5 to 4.7 (maximum)
Chromatin SILAC -/+ UV
Proteins, that are recruited to chromatin in a UV-dependent fashion (This also is the 'input' sample for the CSB-IP experiment)
1.5 to 5.8 (maximum)
Chromatin (MG132) SILAC -/+ UV
Proteins, that are recruited to chromatin in a UV-dependent fashion in the presence of the proteasome inhibitor MG132 (This also is the 'input' sample for the CSB-IP (MG132) and RNAPII-IP (MG132) experiment)
1.5 to 9.0 (maximum)
Phosphorylation SILAC -/+ UV
Proteins, that are increasingly phosphorylated after UV-treatment
1.5 to 9.5 (maximum)
Phosphorylation (MG132) SILAC -/+ UV
Proteins, that are increasingly phosphorylated after UV-treatment in the presence of the proteasome inhibitor MG132
1.5 to 10.7 (maximum)
Ubiquitylation SILAC -/+ UV
Proteins, that are increasingly ubiquitylated after UV-treatment
1.5 to 9.5 (maximum)
Ubiquitylation (MG132) SILAC -/+ UV
Proteins, that are increasingly ubiquitylated after UV-treatment in the presence of the proteasome inhibitor MG132
1.5 to 10.7 (maximum)



Select genes based on global scores


Show genes that have scored in at least individual screens

Show genes that are in the top based on the aggregated z-scores from all experiments

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