RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
ITPR3	2	-0.190	-0.500				1.489	1.835
AKT3	2	0.580	-0.030	-0.194
AKT3	2	0.580	-0.030
ITPR1	2	-0.040	0.000				1.489	1.835
ITPR1	2	-0.040	0.000				0.768	0.643
RAF1	1	2.020	-1.230
TERF2IP	1	0.500	-0.780	-0.491	1.304	2.217	-1.505	-0.760
TERF2IP	1	1.450	-1.010	-0.491	1.304	2.217	-1.505	-0.760
TERF2IP	1	1.580	-0.650	-0.491	1.304	2.217	-1.505	-0.760
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
PLCB4	0	0.640	-0.400
ASAH1	0	-0.300	0.340
AKT2	0	-1.420	2.210	-0.194
SOS1	0	0.500	-0.620	-0.570
ITPR2	0	-1.020	0.610				0.952	0.981
EPHB2	0	-0.630	0.780					0.221
EPHB2	0	-0.630	0.780
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
EGFR	0	-0.580	0.520				0.513	0.090
BRAF	0
STAT3	0	0.200	-1.270					0.334
DAG1	0	0.210	-0.400
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
PLCB1	0	-0.300	-0.220
SRC	0	0.050	0.470	-0.031
CFB	0	-0.380	-0.210

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
AKT2	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT2	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT2	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT2	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT2	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
AKT3	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT3	Ubiquitylation	K14	4.941	5.277	_EGWVQK(gl)R_
AKT3	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT3	Phosphorylation	S120		1.097	_MNCS(ph)PTSQIDNIGEEEMDASTTHHK_
AKT3	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT3	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT3	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
ASAH1	Ubiquitylation	K461		0.139	_ESLDVYELDAK(gl)QGR_
BRAF	Phosphorylation	S151	-0.685	-0.629	_SNPKS(ph)PQKPIVR_
BRAF	Phosphorylation	S363	-0.023	-0.241	_S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S365	-0.286	0.012	_SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S399	-0.890	-0.527	_GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF	Phosphorylation	T401	-0.525		_GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF	Phosphorylation	S446	0.246	0.349	_RDS(ph)SDDWEIPDGQITVGQR_
BRAF	Phosphorylation	S447	0.579	0.623	_RDSS(ph)DDWEIPDGQITVGQR_
BRAF	Phosphorylation	S729	0.208	0.219	_SAS(ph)EPSLNR_
CFB	Ubiquitylation	K808	-6.292		_VASYGVK(gl)PR_
DAG1	Ubiquitylation	K793		0.843	_LTLEDQATFIK(gl)K_
DAG1	Ubiquitylation	K794	0.899		_LTLEDQATFIKK(gl)_
DAG1	Ubiquitylation	K881	-0.342		_GSRPK(gl)NMTPYR_
EGFR	Phosphorylation	T693	0.486	-0.139	_ELVEPLT(ph)PSGEAPNQALLR_
EGFR	Phosphorylation	S991		-0.041	_MHLPS(ph)PTDSNFYR_
EPHB2	Ubiquitylation	K578	-0.752	-0.618	_QSPEDVYFSK(gl)SEQLKPLK_
EPHB2	Ubiquitylation	K583	0.445	0.124	_SEQLK(gl)PLK_
EPHB2	Ubiquitylation	K617	0.339		_QK(gl)VIGAGEFGEVYK_
EPHB2	Ubiquitylation	K649	-1.219		_TLK(gl)AGYTEK_
EPHB2	Phosphorylation	S776	-0.147	-0.171	_FLEDDTS(ph)DPTYTSALGGK_
EPHB2	Phosphorylation	S897		0.000	_LPS(ph)TSGSEGVPFR_
EPHB2	Phosphorylation	T898	-0.329	0.424	_LPST(ph)SGSEGVPFR_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
ITPR1	Ubiquitylation	K529	1.377		_EK(gl)GGEGPLVR_
ITPR1	Phosphorylation	S934	0.318	-0.802	_KQS(ph)VFSAPSLSAGASAAEPLDR_
ITPR1	Phosphorylation	S937		-0.026	_KQSVFS(ph)APSLSAGASAAEPLDR_
ITPR1	Ubiquitylation	K1534		-0.220	_TLAMVAK(gl)GR_
ITPR1	Phosphorylation	S1598	1.165	0.362	_RDS(ph)VLAASR_
ITPR1	Phosphorylation	S1832	0.650	0.560	_VAS(ph)FSIPGSSSR_
ITPR1	Ubiquitylation	K2597		-0.819	_NK(gl)NLDWFPR_
ITPR1	Ubiquitylation	K2628		-0.010	_ILQDK(gl)LNSTMK_
ITPR1	Phosphorylation	S2670	1.132	1.555	_LGFVDVQNCIS(ph)R_
ITPR2	Ubiquitylation	K909		-0.247	_LSK(gl)FQDGGNNVMR_
ITPR2	Phosphorylation	S1160	0.443	0.895	_GGEEPIEESNILS(ph)PVQDGTK_
ITPR3	Ubiquitylation	K529	1.377		_EK(gl)GGEGPLVR_
ITPR3	Phosphorylation	S934	0.318	-0.802	_KQS(ph)VFSAPSLSAGASAAEPLDR_
ITPR3	Phosphorylation	S937		-0.026	_KQSVFS(ph)APSLSAGASAAEPLDR_
ITPR3	Ubiquitylation	K1534		-0.220	_TLAMVAK(gl)GR_
ITPR3	Phosphorylation	S1832	0.650	0.560	_VAS(ph)FSIPGSSSR_
ITPR3	Ubiquitylation	K2597		-0.819	_NK(gl)NLDWFPR_
ITPR3	Ubiquitylation	K2628		-0.010	_ILQDK(gl)LNSTMK_
ITPR3	Phosphorylation	S2670	1.132	1.555	_LGFVDVQNCIS(ph)R_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PLCB1	Phosphorylation	S1199	-0.494		_TPS(ph)SEELGGDIPGKEFDTPL_
PLCB1	Phosphorylation	S1200		-0.483	_TPSS(ph)EELGGDIPGKEFDTPL_
PLCB4	Ubiquitylation	K284	1.083	0.038	_K(gl)GLISSDGFCR_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_
STAT3	Ubiquitylation	K177	0.957		_VVENLQDDFDFNYK(gl)TLK_
STAT3	Ubiquitylation	K180	1.179		_TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3	Ubiquitylation	K244	0.262		_TLTDEELADWK(gl)R_
STAT3	Phosphorylation	T714		-0.338	_FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3	Phosphorylation	S727	-0.079	0.156	_FICVTPTTCSNTIDLPMS(ph)PR_
TERF2IP	Phosphorylation	S36	0.199	-0.039	_DDGSSMSFYVRPS(ph)PAK_
TERF2IP	Phosphorylation	S154	0.255	-0.049	_S(ph)PSSVTGNALWK_
TERF2IP	Phosphorylation	S156	0.369	0.179	_ENARSPS(ph)SVTGNALWK_
TERF2IP	Phosphorylation	S157		0.410	_ENARSPSS(ph)VTGNALWK_
TERF2IP	Phosphorylation	S203	-0.351	-0.260	_YLLGDAPVS(ph)PSSQK_
TERF2IP	Ubiquitylation	K228	-0.229		_KAEEDPEAADSGEPQNK(gl)R_