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Query: ASAH1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ASAH1 0 0.479 -0.300 0.340

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ASAH1 Ubiquitylation K461 0.139 _ESLDVYELDAK(gl)QGR_

Background Information for ASAH1:





Protein-protein Interactions for ASAH1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BUB1B Cat. description Hein, Mann, Cell 2015
Category members IP bait AAGAB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AAMP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AIRE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASAH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP1A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FTH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLT1D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTATIP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNKD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLCO6A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBC1D22B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZIC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF556 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF684 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZSCAN12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ASAH1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Acid_ceramidase-like IPR016699 0
Category members Ntn_hydrolases_N IPR029055 0
Category members CBAH/NAAA_C IPR029132 0


Protein complexes (CORUM database) featuring ASAH1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ASAH1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0030324 lung development Database 0.39
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members Pathway Pathway_733 ST_G_ALPHA_S_PATHWAY 0 0.13
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_735 ST_MYOCYTE_AD_PATHWAY 0 0.09
Category members Pathway Pathway_513 ST_ADRENERGIC 0 0.08
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0043202 lysosomal lumen Database 0.07
Category members Pathway Pathway_518 ST_G_ALPHA_I_PATHWAY 0 0.05
Category members Pathway Pathway_517 ST_GRANULE_CELL_SURVIVAL_PATHWAY 0 0.02
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_126 REACTOME_GLYCOSPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_127 KEGG_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_128 REACTOME_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_216 BIOCARTA_EDG1_PATHWAY 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_445 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS 0 0
Category members Pathway Pathway_516 ST_PAC1_RECEPTOR_PATHWAY 0 0
Category members Pathway Pathway_734 PID_CERAMIDE_PATHWAY 0 0
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006665 sphingolipid metabolic process Database 0
Category members GO Category GO:0006672 ceramide metabolic process Database 0
Category members GO Category GO:0006687 glycosphingolipid metabolic process Database 0
Category members GO Category GO:0010033 response to organic substance Database 0
Category members GO Category GO:0017040 ceramidase activity Database 0


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