Results for the Category
ST_GRANULE_CELL_SURVIVAL_PATHWAY
(Pathway_517)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| JUN | 3 | -0.930 | 0.930 | -0.126 | ||||
| PARP1 | 2 | |||||||
| PARP1 | 2 | -0.200 | 0.357 | 0.412 | 0.442 | 0.293 | ||
| MAPK9 | 1 | 0.110 | -0.490 | |||||
| MAPK8IP2 | 0 | 1.730 | -1.220 | |||||
| MAP2K4 | 0 | -0.300 | 0.320 | |||||
| MAP2K7 | 0 | 0.180 | -0.660 | -2.110 | ||||
| ASAH1 | 0 | -0.300 | 0.340 | |||||
| CREB3 | 0 | 0.180 | -0.820 | |||||
| CREB1 | 0 | 1.080 | -0.800 | -1.027 | ||||
| EPHB2 | 0 | -0.630 | 0.780 | 0.221 | ||||
| EPHB2 | 0 | -0.630 | 0.780 | |||||
| GNAQ | 0 | 0.140 | -0.310 | 0.052 | 0.449 | |||
| CASP3 | 0 | 0.570 | -0.390 | |||||
| DAG1 | 0 | 0.210 | -0.400 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ASAH1 | Ubiquitylation | K461 | 0.139 | _ESLDVYELDAK(gl)QGR_ | |
| CASP3 | Ubiquitylation | K11 | -0.053 | -0.687 | _(ac)MENTENSVDSK(gl)SIK_ |
| CASP3 | Ubiquitylation | K14 | -0.455 | -0.687 | _SIK(gl)NLEPK_ |
| CASP3 | Ubiquitylation | K57 | -0.304 | -1.817 | _NFHK(gl)STGMTSR_ |
| CASP3 | Ubiquitylation | K82 | -0.268 | -0.605 | _NLK(gl)YEVR_ |
| CREB1 | Phosphorylation | S271 | -0.979 | -1.450 | _TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_ |
| CREB1 | Ubiquitylation | K333 | 1.343 | _ALK(gl)DLYCHK_ | |
| CREB3 | Ubiquitylation | K176 | -0.114 | _TEEQILK(gl)R_ | |
| DAG1 | Ubiquitylation | K793 | 0.843 | _LTLEDQATFIK(gl)K_ | |
| DAG1 | Ubiquitylation | K794 | 0.899 | _LTLEDQATFIKK(gl)_ | |
| DAG1 | Ubiquitylation | K881 | -0.342 | _GSRPK(gl)NMTPYR_ | |
| EPHB2 | Ubiquitylation | K578 | -0.752 | -0.618 | _QSPEDVYFSK(gl)SEQLKPLK_ |
| EPHB2 | Ubiquitylation | K583 | 0.445 | 0.124 | _SEQLK(gl)PLK_ |
| EPHB2 | Ubiquitylation | K617 | 0.339 | _QK(gl)VIGAGEFGEVYK_ | |
| EPHB2 | Ubiquitylation | K649 | -1.219 | _TLK(gl)AGYTEK_ | |
| EPHB2 | Phosphorylation | S776 | -0.147 | -0.171 | _FLEDDTS(ph)DPTYTSALGGK_ |
| EPHB2 | Phosphorylation | S897 | 0.000 | _LPS(ph)TSGSEGVPFR_ | |
| EPHB2 | Phosphorylation | T898 | -0.329 | 0.424 | _LPST(ph)SGSEGVPFR_ |
| GNAQ | Ubiquitylation | K16 | 0.245 | _TLESIMACCLSEEAK(gl)EAR_ | |
| GNAQ | Ubiquitylation | K102 | -0.299 | _IPYK(gl)YEHNK_ | |
| JUN | Phosphorylation | S58 | -0.167 | -1.247 | _AKNS(ph)DLLTSPDVGLLK_ |
| JUN | Phosphorylation | T62 | 2.545 | 1.674 | _NSDLLT(ph)SPDVGLLK_ |
| JUN | Phosphorylation | S63 | 2.030 | 1.458 | _NSDLLTS(ph)PDVGLLK_ |
| JUN | Ubiquitylation | K70 | 9.213 | _NSDLLTSPDVGLLK(gl)_ | |
| JUN | Phosphorylation | S73 | 1.499 | 0.845 | _LAS(ph)PELER_ |
| JUN | Phosphorylation | S243 | -0.642 | -1.399 | _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_ |
| JUN | Ubiquitylation | K309 | 1.034 | 0.155 | _EQVAQLK(gl)QK_ |
| MAP2K4 | Phosphorylation | S80 | 0.441 | _LRTHS(ph)IESSGK_ | |
| MAP2K7 | Ubiquitylation | K9 | -1.406 | _(ac)AASSLEQK(gl)LSR_ | |
| MAP2K7 | Ubiquitylation | K300 | -1.228 | _GQIK(gl)LCDFGISGR_ | |
| MAP2K7 | Ubiquitylation | K442 | -1.326 | _DVMAK(gl)TESPR_ | |
| MAPK8IP2 | Ubiquitylation | K674 | -0.899 | 0.671 | _DLLGSK(gl)R_ |
| MAPK9 | Phosphorylation | Y185 | 3.533 | _TACTNFMMTPY(ph)VVTR_ | |
| PARP1 | Phosphorylation | S41 | -0.803 | _MAIMVQS(ph)PMFDGK_ | |
| PARP1 | Ubiquitylation | K84 | 1.223 | _WDDQQK(gl)VK_ | |
| PARP1 | Ubiquitylation | K86 | 1.058 | _VK(gl)KTAEAGGVTGK_ | |
| PARP1 | Ubiquitylation | K87 | 1.058 | _VK(gl)KTAEAGGVTGK_ | |
| PARP1 | Ubiquitylation | K97 | 1.386 | 0.406 | _TAEAGGVTGK(gl)GQDGIGSK_ |
| PARP1 | Ubiquitylation | K105 | 0.828 | _GQDGIGSK(gl)AEK_ | |
| PARP1 | Ubiquitylation | K108 | 1.317 | _GQDGIGSKAEK(gl)_ | |
| PARP1 | Ubiquitylation | K119 | 1.569 | _TLGDFAAEYAK(gl)SNR_ | |
| PARP1 | Ubiquitylation | K131 | 1.025 | 1.620 | _GCMEK(gl)IEK_ |
| PARP1 | Ubiquitylation | K197 | 0.445 | 1.157 | _K(gl)QLPGVK_ |
| PARP1 | Ubiquitylation | K254 | 0.589 | _AQNDLIWNIKDELKK(gl)_ | |
| PARP1 | Ubiquitylation | K262 | 0.456 | _VCSTNDLK(gl)ELLIFNK_ | |
| PARP1 | Ubiquitylation | K320 | 1.464 | 1.034 | _SDAYYCTGDVTAWTK(gl)CMVK_ |
| PARP1 | Ubiquitylation | K331 | -0.425 | -0.480 | _TQTPNRK(gl)EWVTPK_ |
| PARP1 | Ubiquitylation | K337 | 0.462 | 0.332 | _EWVTPK(gl)EFR_ |
| PARP1 | Ubiquitylation | K346 | 0.370 | 0.411 | _EISYLK(gl)K_ |
| PARP1 | Phosphorylation | T368 | -1.474 | -1.410 | _IFPPETSASVAAT(ph)PPPSTASAPAAVNSSASADKPLSNM(ox)K_ |
| PARP1 | Ubiquitylation | K400 | 0.844 | 1.095 | _ILTLGK(gl)LSR_ |
| PARP1 | Ubiquitylation | K414 | 1.227 | 1.241 | _AMIEK(gl)LGGK_ |
| PARP1 | Ubiquitylation | K418 | 1.131 | _LGGK(gl)LTGTANK_ | |
| PARP1 | Ubiquitylation | K425 | 0.912 | 0.815 | _LTGTANK(gl)ASLCISTKK_ |
| PARP1 | Ubiquitylation | K433 | 0.942 | _ASLCISTK(gl)K_ | |
| PARP1 | Ubiquitylation | K434 | 0.020 | _ASLCISTKK(gl)_ | |
| PARP1 | Ubiquitylation | K447 | 1.480 | _MEEVK(gl)EANIR_ | |
| PARP1 | Ubiquitylation | K518 | 0.108 | _GQVKEEGINK(gl)SEK_ | |
| PARP1 | Ubiquitylation | K521 | 0.630 | _GQVKEEGINKSEK(gl)R_ | |
| PARP1 | Ubiquitylation | K548 | 0.125 | -0.480 | _GGAAVDPDSGLEHSAHVLEK(gl)GGK_ |
| PARP1 | Ubiquitylation | K551 | 0.492 | -0.573 | _GGAAVDPDSGLEHSAHVLEKGGK(gl)_ |
| PARP1 | Ubiquitylation | K629 | 1.632 | _TGNAWHSK(gl)NFTK_ | |
| PARP1 | Ubiquitylation | K633 | 0.964 | 0.091 | _NFTK(gl)YPK_ |
| PARP1 | Ubiquitylation | K654 | -0.086 | _K(gl)LTVNPGTK_ | |
| PARP1 | Ubiquitylation | K662 | 0.112 | _LTVNPGTK(gl)SK_ | |
| PARP1 | Ubiquitylation | K664 | -0.042 | -0.111 | _LTVNPGTKSK(gl)_ |
| PARP1 | Ubiquitylation | K683 | 0.983 | 1.355 | _MIFDVESM(ox)K(gl)K_ |
| PARP1 | Ubiquitylation | K684 | 1.213 | 1.355 | _MIFDVESMKK(gl)_ |
| PARP1 | Ubiquitylation | K700 | 0.448 | _MPLGK(gl)LSK_ | |
| PARP1 | Phosphorylation | S782 | 0.648 | 0.490 | _GGS(ph)DDSSKDPIDVNYEK_ |
| PARP1 | Ubiquitylation | K949 | 0.738 | _HSVK(gl)GLGK_ |
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© Copyright Svejstrup Laboratory 2015