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Query: MAPK9

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAPK9 1 3.533 0.110 -0.490

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_

Background Information for MAPK9:


Pubmed-MAPK9 »
Uniprot-MAPK9 »
Biogrid-MAPK9 »
ProteomicsDB-MAPK9 »

Tumorportal-MAPK9 »
COSMIC-MAPK9 »
GenomeRNAi-MAPK9 »
Genecards-MAPK9


Protein-protein Interactions for MAPK9
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C5orf24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC120 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOXC10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC56 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK8IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASL10B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RHPN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFC3H1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF414 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAPK9
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members MAPK_JNK IPR008351 0
Category members LipoPS_kinase IPR010440 0
Category members RIO-like_kinase IPR018934 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring MAPK9
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAPK9
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_416 PID_P53_REGULATION_PATHWAY 0 2.29
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members Pathway Pathway_541 PID_FAK_PATHWAY 0 1.88
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_1023 PID_NFAT_3PATHWAY 0 1.46
Category members Pathway Pathway_309 ST_INTEGRIN_SIGNALING_PATHWAY 0 1.35
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members Pathway Pathway_634 KEGG_COLORECTAL_CANCER 0 0.98
Category members Pathway Pathway_118 PID_FOXO_PATHWAY 0 0.97
Category members Pathway Pathway_608 SIG_CD40PATHWAYMAP 0 0.89
Category members Pathway Pathway_529 KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 0 0.75
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members Pathway Pathway_568 PID_CDC42_PATHWAY 0 0.68
Category members GO Category GO:0042493 response to drug Database 0.66
Category members Pathway Pathway_220 KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION 0 0.6
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0034644 cellular response to UV Database 0.49
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0038095 Fc-epsilon receptor signaling pathway Database 0.36
Category members Pathway Pathway_45 PID_REG_GR_PATHWAY 0 0.31
Category members GO Category GO:0035666 TRIF-dependent toll-like receptor signaling pathway Database 0.29
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0034138 toll-like receptor 3 signaling pathway Database 0.28
Category members GO Category GO:0034142 toll-like receptor 4 signaling pathway Database 0.27
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0002756 MyD88-independent toll-like receptor signaling pathway Database 0.25
Category members Pathway Pathway_1053 KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0.25
Category members Pathway Pathway_587 KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.25
Category members Pathway Pathway_188 KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION 0 0.24
Category members GO Category GO:0009612 response to mechanical stimulus Database 0.23
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0001934 positive regulation of protein phosphorylation Database 0.22
Category members GO Category GO:0046328 regulation of JNK cascade Database 0.22
Category members Pathway Pathway_406 PID_RB_1PATHWAY 0 0.21
Category members Pathway Pathway_826 REACTOME_ACTIVATED_TLR4_SIGNALLING 0 0.21
Category members Pathway Pathway_44 KEGG_INSULIN_SIGNALING_PATHWAY 0 0.21
Category members Pathway Pathway_1001 REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES 0 0.2
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0001836 release of cytochrome c from mitochondria Database 0.18
Category members Pathway Pathway_555 PID_NEPHRIN_NEPH1_PATHWAY 0 0.17
Category members Pathway Pathway_527 REACTOME_TOLL_RECEPTOR_CASCADES 0 0.17
Category members Pathway Pathway_649 KEGG_PANCREATIC_CANCER 0 0.15
Category members Pathway Pathway_532 PID_ERBB2_ERBB3_PATHWAY 0 0.13
Category members Pathway Pathway_797 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION 0 0.12
Category members GO Category GO:0002224 toll-like receptor signaling pathway Database 0.12
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0006626 protein targeting to mitochondrion Database 0.11
Category members GO Category GO:0014075 response to amine Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_813 REACTOME_TRIF_MEDIATED_TLR3_SIGNALING 0 0.11
Category members Pathway Pathway_601 PID_IL2_1PATHWAY 0 0.1
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members Pathway Pathway_417 PID_WNT_NONCANONICAL_PATHWAY 0 0.09
Category members Pathway Pathway_997 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS 0 0.09
Category members GO Category GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process Database 0.08
Category members Pathway Pathway_418 PID_ATF2_PATHWAY 0 0.08
Category members GO Category GO:0045429 positive regulation of nitric oxide biosynthetic process Database 0.06
Category members Pathway Pathway_814 REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE 0 0.05
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_996 REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE 0 0.05
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_557 PID_P75_NTR_PATHWAY 0 0.04
Category members Pathway Pathway_834 REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE 0 0.04
Category members GO Category GO:0004707 MAP kinase activity Database 0.04
Category members GO Category GO:0034146 toll-like receptor 5 signaling pathway Database 0.04
Category members GO Category GO:0034166 toll-like receptor 10 signaling pathway Database 0.04
Category members GO Category GO:0034162 toll-like receptor 9 signaling pathway Database 0.04
Category members GO Category GO:0071356 cellular response to tumor necrosis factor Database 0.03
Category members GO Category GO:0051090 regulation of sequence-specific DNA binding transcription factor activity Database 0.02
Category members Pathway Pathway_386 ST_FAS_SIGNALING_PATHWAY 0 0.02
Category members Pathway Pathway_517 ST_GRANULE_CELL_SURVIVAL_PATHWAY 0 0.02
Category members GO Category GO:0034134 toll-like receptor 2 signaling pathway Database 0.01
Category members GO Category GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process Database 0.01
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0010744 positive regulation of macrophage derived foam cell differentiation Database 0
Category members Pathway Pathway_1000 BIOCARTA_MAPK_PATHWAY 0 0
Category members Pathway Pathway_1121 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 0 0
Category members Pathway Pathway_21 ST_JNK_MAPK_PATHWAY 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_257 KEGG_GNRH_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_40 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_445 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS 0 0
Category members Pathway Pathway_483 KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_530 KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_575 KEGG_ERBB_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_612 KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_650 PID_FAS_PATHWAY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_897 PID_CD8_TCR_DOWNSTREAM_PATHWAY 0 0
Category members Pathway Pathway_904 PID_IL12_STAT4_PATHWAY 0 0
Category members Pathway Pathway_97 KEGG_TYPE_II_DIABETES_MELLITUS 0 0
Category members Pathway Pathway_986 PID_CD40_PATHWAY 0 0
Category members GO Category GO:0002755 MyD88-dependent toll-like receptor signaling pathway Database 0
Category members GO Category GO:0004705 JUN kinase activity Database 0
Category members GO Category GO:0006950 response to stress Database 0
Category members GO Category GO:0007254 JNK cascade Database 0
Category members GO Category GO:0007258 JUN phosphorylation Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Database 0
Category members GO Category GO:0009103 lipopolysaccharide biosynthetic process Database 0
Category members GO Category GO:0009636 response to toxic substance Database 0
Category members GO Category GO:0010033 response to organic substance Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0031394 positive regulation of prostaglandin biosynthetic process Database 0
Category members GO Category GO:0031396 regulation of protein ubiquitination Database 0
Category members GO Category GO:0031435 mitogen-activated protein kinase kinase kinase binding Database 0
Category members GO Category GO:0032308 positive regulation of prostaglandin secretion Database 0
Category members GO Category GO:0032722 positive regulation of chemokine production Database 0
Category members GO Category GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway Database 0
Category members GO Category GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway Database 0
Category members GO Category GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0046686 response to cadmium ion Database 0
Category members GO Category GO:0051403 stress-activated MAPK cascade Database 0
Category members GO Category GO:0071222 cellular response to lipopolysaccharide Database 0
Category members GO Category GO:0071347 cellular response to interleukin-1 Database 0
Category members GO Category GO:0071363 cellular response to growth factor stimulus Database 0


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