Results for the Category
SIG_CD40PATHWAYMAP
(Pathway_608)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| MAPK14 | 2 | -0.160 | -0.350 | |||||
| MAPK9 | 1 | 0.110 | -0.490 | |||||
| TRAF2 | 1 | -0.570 | 0.540 | |||||
| TRAF2 | 1 | -0.570 | 0.540 | |||||
| TONSL | 1 | -1.900 | 3.540 | -0.261 | -3.160 | 0.665 | 1.051 | |
| MAPK8IP2 | 0 | 1.730 | -1.220 | |||||
| MAP2K4 | 0 | -0.300 | 0.320 | |||||
| MAP2K7 | 0 | 0.180 | -0.660 | -2.110 | ||||
| NFKB2 | 0 | 1.750 | -0.820 | |||||
| MAPKAPK5 | 0 | 1.100 | -0.730 | |||||
| MAPK3 | 0 | |||||||
| NFKB1 | 0 | 0.720 | -0.810 | |||||
| GORASP1 | 0 | -0.370 | 0.290 | |||||
| DUSP1 | 0 | 0.290 | -0.100 | |||||
| PIK3CA | 0 | |||||||
| TRAF3 | 0 | -1.050 | 1.040 | |||||
| PIK3R1 | 0 | 1.910 | -1.220 | -0.441 | 0.147 | |||
| NFKBIE | 0 | 1.270 | -0.670 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| DUSP1 | Ubiquitylation | K97 | -0.523 | _SAALDGAK(gl)R_ | |
| GORASP1 | Ubiquitylation | K169 | -0.209 | -0.035 | _LMVYNSK(gl)SDSCR_ |
| GORASP1 | Phosphorylation | T216 | -2.224 | -1.869 | _KPPGT(ph)PPPSALPLGAPPPDALPPGPTPEDSPS(ph)LETGSR_ |
| MAP2K4 | Phosphorylation | S80 | 0.441 | _LRTHS(ph)IESSGK_ | |
| MAP2K7 | Ubiquitylation | K9 | -1.406 | _(ac)AASSLEQK(gl)LSR_ | |
| MAP2K7 | Ubiquitylation | K300 | -1.228 | _GQIK(gl)LCDFGISGR_ | |
| MAP2K7 | Ubiquitylation | K442 | -1.326 | _DVMAK(gl)TESPR_ | |
| MAPK14 | Phosphorylation | S2 | 3.221 | 3.623 | _(ac)S(ph)QERPTFYR_ |
| MAPK14 | Phosphorylation | T180 | 0.958 | 1.087 | _HTDDEM(ox)T(ph)GYVATR_ |
| MAPK14 | Phosphorylation | Y182 | 1.388 | 1.374 | _HTDDEM(ox)TGY(ph)VATR_ |
| MAPK14 | Ubiquitylation | K249 | 0.073 | -1.380 | _LVGTPGAELLKK(gl)_ |
| MAPK3 | Phosphorylation | Y204 | -0.807 | -2.487 | _IADPEHDHTGFLTEY(ph)VATR_ |
| MAPK3 | Ubiquitylation | K289 | -0.608 | _NYLQSLPSKTK(gl)_ | |
| MAPK8IP2 | Ubiquitylation | K674 | -0.899 | 0.671 | _DLLGSK(gl)R_ |
| MAPK9 | Phosphorylation | Y185 | 3.533 | _TACTNFMMTPY(ph)VVTR_ | |
| MAPKAPK5 | Phosphorylation | T182 | -0.559 | -0.706 | _IDQGDLM(ox)T(ph)PQFTPYYVAPQVLEAQR_ |
| NFKB1 | Phosphorylation | S907 | -0.025 | 0.113 | _TTSQAHSLPLS(ph)PASTR_ |
| NFKB2 | Ubiquitylation | K741 | -2.393 | _GHTPLDLTCSTK(gl)VK_ | |
| NFKB2 | Ubiquitylation | K743 | -0.624 | _GHTPLDLTCSTKVK(gl)_ | |
| NFKBIE | Ubiquitylation | K316 | -0.248 | _ALVLK(gl)GASR_ | |
| PIK3CA | Ubiquitylation | K864 | 0.390 | 0.588 | _NSHTIM(ox)QIQCK(gl)GGLK_ |
| PIK3CA | Ubiquitylation | K868 | 0.204 | 0.651 | _NSHTIM(ox)QIQCKGGLK(gl)_ |
| PIK3CA | Ubiquitylation | K974 | -0.273 | _GAQECTK(gl)TREFER_ | |
| TONSL | Ubiquitylation | K336 | -1.432 | _AAEAYQK(gl)QLR_ | |
| TONSL | Phosphorylation | S719 | -0.359 | -0.212 | _VS(ph)PGQAAPAMARPR_ |
| TRAF2 | Phosphorylation | T7 | -0.822 | -1.190 | _(ac)AAASVT(ph)PPGSLELLQPGFSK_ |
| TRAF2 | Ubiquitylation | K27 | -0.253 | 2.194 | _TLLGTK(gl)LEAK_ |
| TRAF2 | Ubiquitylation | K119 | 0.519 | _GTLK(gl)EYESCHEGR_ | |
| TRAF2 | Ubiquitylation | K176 | -1.233 | 1.022 | _APCCGADVK(gl)AHHEVCPK_ |
| TRAF2 | Ubiquitylation | K207 | 0.147 | 0.918 | _FQDHVK(gl)TCGK_ |
| TRAF2 | Ubiquitylation | K481 | -0.507 | 0.417 | _MEAK(gl)NSYVR_ |
| TRAF3 | Ubiquitylation | K369 | -1.061 | -2.137 | _VTELESVDK(gl)SAGQVAR_ |
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