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Query: DUSP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DUSP1 0 -0.523 0.290 -0.100

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DUSP1 Ubiquitylation K97 -0.523 _SAALDGAK(gl)R_

Background Information for DUSP1:


Pubmed-DUSP1 »
Uniprot-DUSP1 »
Biogrid-DUSP1 »
ProteomicsDB-DUSP1 »

Tumorportal-DUSP1 »
COSMIC-DUSP1 »
GenomeRNAi-DUSP1 »
Genecards-DUSP1


Protein-protein Interactions for DUSP1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in DUSP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Atypical_DUSP IPR020417 0.23
Category members Tyr_Pase_rcpt/non-rcpt IPR000242 0
Category members Dual-sp_phosphatase_cat-dom IPR000340 0
Category members Tyr/Dual-sp_Pase IPR000387 0
Category members Rhodanese-like_dom IPR001763 0
Category members Tyr_Pase_cat IPR003595 0
Category members MKP IPR008343 0
Category members Dual-sp_phosphatase_subgr_cat IPR020422 0
Category members Prot-tyrosine_phosphatase-like IPR029021 0


Protein complexes (CORUM database) featuring DUSP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DUSP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members Pathway Pathway_608 SIG_CD40PATHWAYMAP 0 0.89
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members Pathway Pathway_983 ST_P38_MAPK_PATHWAY 0 0.34
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members GO Category GO:0042542 response to hydrogen peroxide Database 0.19
Category members GO Category GO:0001706 endoderm formation Database 0.08
Category members Pathway Pathway_418 PID_ATF2_PATHWAY 0 0.08
Category members GO Category GO:0009416 response to light stimulus Database 0.06
Category members GO Category GO:0008330 protein tyrosine/threonine phosphatase activity Database 0.05
Category members Pathway Pathway_150 BIOCARTA_PPARA_PATHWAY 0 0.04
Category members GO Category GO:0051384 response to glucocorticoid Database 0.04
Category members Pathway Pathway_1039 PID_P38_ALPHA_BETA_PATHWAY 0 0
Category members Pathway Pathway_1044 BIOCARTA_NTHI_PATHWAY 0 0
Category members Pathway Pathway_1045 BIOCARTA_TNFR2_PATHWAY 0 0
Category members Pathway Pathway_1055 BIOCARTA_CD40_PATHWAY 0 0
Category members Pathway Pathway_443 PID_AP1_PATHWAY 0 0
Category members Pathway Pathway_500 PID_FCER1_PATHWAY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000188 inactivation of MAPK activity Database 0
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0004726 non-membrane spanning protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0006979 response to oxidative stress Database 0
Category members GO Category GO:0008138 protein tyrosine/serine/threonine phosphatase activity Database 0
Category members GO Category GO:0010033 response to organic substance Database 0
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity Database 0
Category members GO Category GO:0032355 response to estradiol Database 0
Category members GO Category GO:0032526 response to retinoic acid Database 0
Category members GO Category GO:0032870 cellular response to hormone stimulus Database 0
Category members GO Category GO:0033574 response to testosterone Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0051447 negative regulation of meiotic cell cycle Database 0
Category members GO Category GO:0051591 response to cAMP Database 0
Category members GO Category GO:0051592 response to calcium ion Database 0


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