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BIOCARTA_TNFR2_PATHWAY
(Pathway_1045)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
TRAF2 1 -0.570 0.540
TRAF2 1 -0.570 0.540
TANK 1 0.110 0.120
IKBKAP 0 -0.760 1.050 0.446 0.516 -0.004 0.427 0.134
MAP3K1 0 0.750 -1.270
IKBKB 0 0.400 0.610
NFKB1 0 0.720 -0.810
TNFAIP3 0 0.760 -0.500
DUSP1 0 0.290 -0.100
TRAF3 0 -1.050 1.040
RIPK1 0 -0.190 0.440
RELA 0 -1.130 1.600 0.793
CHUK 0 -0.480

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CHUK Ubiquitylation K296 -1.637 _GGPVDLTLK(gl)QPR_
DUSP1 Ubiquitylation K97 -0.523 _SAALDGAK(gl)R_
IKBKAP Ubiquitylation K716 -1.287 _IVTVVPQDTK(gl)LVLQMPR_
IKBKB Ubiquitylation K106 0.253 _K(gl)YLNQFENCCGLR_
IKBKB Phosphorylation S672 0.670 0.244 _GPVSGS(ph)PDSMNASR_
MAP3K1 Phosphorylation S292 0.209 _RAPS(ph)PDGFSPYSPEETNR_
MAP3K1 Phosphorylation S506 1.427 _SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1 Phosphorylation S507 1.436 _SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1 Phosphorylation S923 0.127 -0.120 _LSAS(ph)SEDISER_
NFKB1 Phosphorylation S907 -0.025 0.113 _TTSQAHSLPLS(ph)PASTR_
RIPK1 Ubiquitylation K642 -0.431 _EGIK(gl)GATVGK_
TANK Ubiquitylation K195 -2.273 0.787 _QEALFK(gl)PQAK_
TANK Ubiquitylation K199 -1.047 _TDKQEALFKPQAK(gl)DDINR_
TANK Ubiquitylation K231 -0.635 1.969 _GLCRDEEDTSFESLSK(gl)FNVK_
TANK Ubiquitylation K308 -0.969 _TTDK(gl)TKPSNLVNTCIR_
TANK Ubiquitylation K310 -0.969 _TTDK(gl)TKPSNLVNTCIR_
TNFAIP3 Ubiquitylation K722 0.496 0.176 _ASCK(gl)NILACR_
TRAF2 Phosphorylation T7 -0.822 -1.190 _(ac)AAASVT(ph)PPGSLELLQPGFSK_
TRAF2 Ubiquitylation K27 -0.253 2.194 _TLLGTK(gl)LEAK_
TRAF2 Ubiquitylation K119 0.519 _GTLK(gl)EYESCHEGR_
TRAF2 Ubiquitylation K176 -1.233 1.022 _APCCGADVK(gl)AHHEVCPK_
TRAF2 Ubiquitylation K207 0.147 0.918 _FQDHVK(gl)TCGK_
TRAF2 Ubiquitylation K481 -0.507 0.417 _MEAK(gl)NSYVR_
TRAF3 Ubiquitylation K369 -1.061 -2.137 _VTELESVDK(gl)SAGQVAR_


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