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Query: TANK

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TANK 1 1.455 0.110 0.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TANK Ubiquitylation K231 -0.635 1.969 _GLCRDEEDTSFESLSK(gl)FNVK_
TANK Ubiquitylation K195 -2.273 0.787 _QEALFK(gl)PQAK_
TANK Ubiquitylation K199 -1.047 _TDKQEALFKPQAK(gl)DDINR_
TANK Ubiquitylation K308 -0.969 _TTDK(gl)TKPSNLVNTCIR_
TANK Ubiquitylation K310 -0.969 _TTDK(gl)TKPSNLVNTCIR_

Background Information for TANK:


Pubmed-TANK »
Uniprot-TANK »
Biogrid-TANK »
ProteomicsDB-TANK »

Tumorportal-TANK »
COSMIC-TANK »
GenomeRNAi-TANK »
Genecards-TANK


Protein-protein Interactions for TANK
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BBOX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKBKG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TANK
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring TANK
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5212 Kinase maturation complex 2 Database 0.18
Category members Corum 5210 TANK-TRAF2-TRAF3 complex Database 0


Categories featuring TANK
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members Pathway Pathway_484 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS 0 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_1045 BIOCARTA_TNFR2_PATHWAY 0 0
Category members Pathway Pathway_1046 BIOCARTA_STRESS_PATHWAY 0 0
Category members Pathway Pathway_1165 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION 0 0
Category members Pathway Pathway_483 KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007249 I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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