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Query: IKBKAP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IKBKAP 0 1.282 -0.760 1.050 0.446 0.516 -0.004 0.427 0.134

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IKBKAP Ubiquitylation K716 -1.287 _IVTVVPQDTK(gl)LVLQMPR_

Background Information for IKBKAP:


Pubmed-IKBKAP »
Uniprot-IKBKAP »
Biogrid-IKBKAP »
ProteomicsDB-IKBKAP »

Tumorportal-IKBKAP »
COSMIC-IKBKAP »
GenomeRNAi-IKBKAP »
Genecards-IKBKAP


Protein-protein Interactions for IKBKAP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IKBKAP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members UBA-like IPR009060 0.17


Protein complexes (CORUM database) featuring IKBKAP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1380 Elongator holo complex Database 0
Category members Corum 2105 IkappaB kinase complex (IKBKB, CHUK, IKBKAP, NFKBIA, RELA, MAP3K14) Database 0
Category members Corum 2716 Elongator core complex Database 0


Categories featuring IKBKAP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006368 transcription elongation from RNA polymerase II promoter Database 2.03
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016591 DNA-directed RNA polymerase II, holoenzyme Database 1.52
Category members GO Category GO:0006955 immune response Database 1.22
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_1045 BIOCARTA_TNFR2_PATHWAY 0 0
Category members Pathway Pathway_1055 BIOCARTA_CD40_PATHWAY 0 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008023 transcription elongation factor complex Database 0
Category members GO Category GO:0008607 phosphorylase kinase regulator activity Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0033588 Elongator holoenzyme complex Database 0


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