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DNA-directed RNA polymerase II, holoenzyme
(GO:0016591)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RPRD1B 1 -0.280 0.460 0.234 1.123 2.253 -0.005 0.487
RPRD1B 1 -0.280 0.460 0.178 1.395 2.538 -0.102 0.850
RECQL5 1 -0.670 1.270 3.649 0.084 1.224
ERCC5 1 -2.410 5.420
RPRD1A 1 -1.170 2.460 0.234 1.123 2.253 -0.005 0.487
MYO6 1 -1.580 2.560 0.037 0.700 0.607
MYO6 1 -1.580 2.560 -0.533
IKBKAP 0 -0.760 1.050 0.446 0.516 -0.004 0.427 0.134
ELP4 0 1.540 -0.580
CCNC 0 0.760 -0.860
RPAP2 0 -0.440 -0.220 -0.533
ELP3 0 -0.130 0.500
ELP3 0 -0.130 0.500 0.575
CCNH 0 1.480 -0.550
ELP2 0 0.130 -0.470 0.142
POLR2M 0 -0.020 0.080
POLR2M 0 -0.020 0.080 -0.361
POLR2M 0 -0.020 0.080

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CCNC Ubiquitylation K117 0.126 _LIAAATSVLK(gl)TR_
CCNH Ubiquitylation K189 0.418 _K(gl)TADDFLNR_
ELP2 Ubiquitylation K484 -0.739 _LFAPWK(gl)R_
ELP2 Ubiquitylation K524 0.072 -0.086 _FQFVSGADEK(gl)VLR_
ELP3 Ubiquitylation K5 0.857 -0.808 _LK(gl)AKPIR_
ELP3 Ubiquitylation K34 0.744 _QLIEAHEQGK(gl)DIDLNK_
ELP3 Ubiquitylation K40 0.708 _DIDLNK(gl)VK_
ELP3 Ubiquitylation K42 0.650 _DIDLNKVK(gl)TK_
ELP3 Ubiquitylation K77 0.857 -0.808 _LK(gl)AKPIR_
ELP3 Ubiquitylation K333 0.344 _GTGLYELWK(gl)SGR_
ELP3 Ubiquitylation K392 0.034 _MK(gl)DLGIQCR_
ELP4 Ubiquitylation K406 0.254 -0.819 _MDLAESAK(gl)R_
ERCC5 Phosphorylation S766 -0.289 -0.748 _LKTEKEPDATPPS(ph)PR_
ERCC5 Phosphorylation S809 -0.115 0.693 _NAPAAVDEGSIS(ph)PR_
ERCC5 Ubiquitylation K858 0.818 1.193 _INSSTENSDEGLK(gl)VR_
ERCC5 Phosphorylation S951 -0.018 -0.048 _ELTPAS(ph)PTCTNSVSK_
ERCC5 Phosphorylation S988 0.598 1.186 _FDSSLLSS(ph)DDETK_
IKBKAP Ubiquitylation K716 -1.287 _IVTVVPQDTK(gl)LVLQMPR_
MYO6 Phosphorylation S266 0.008 _LHLS(ph)SPDNFR_
MYO6 Phosphorylation S267 -0.106 0.501 _LHLSS(ph)PDNFR_
MYO6 Ubiquitylation K285 0.079 _YFANK(gl)ETDKQILQNR_
MYO6 Ubiquitylation K408 0.078 _GTVIK(gl)VPLKVEQANNAR_
MYO6 Ubiquitylation K634 0.366 _ELFESSTNNNKDTKQK(gl)_
MYO6 Ubiquitylation K993 -0.079 1.133 _QK(gl)EEESQQQAVLEQERR_
MYO6 Ubiquitylation K1053 -1.790 _NDGTRPK(gl)MTPEQMAK_
MYO6 Ubiquitylation K1077 -0.135 0.805 _GPAVLATK(gl)AAAGTK_
MYO6 Ubiquitylation K1089 0.440 1.326 _YDLSK(gl)WK_
MYO6 Ubiquitylation K1120 0.732 0.435 _LK(gl)VYHAWK_
MYO6 Ubiquitylation K1126 0.296 _VYHAWK(gl)SK_
MYO6 Ubiquitylation K1142 -1.182 -0.570 _NTETEQRAPK(gl)SVTDYAQQNPAAQIPAR_
MYO6 Ubiquitylation K1184 -1.200 -0.624 _IPFIRPADQYK(gl)DPQSK_
POLR2M Phosphorylation S10 -1.111 -1.528 _APES(ph)PPSADPALVAGPAEEAECPPPR_
POLR2M Phosphorylation S575 1.290 _VS(ph)SQAEDTSSSFDNLFIDR_
POLR2M Phosphorylation S667 0.502 0.499 _SGS(ph)PISSEERR_
RECQL5 Phosphorylation S727 -0.587 -0.527 _GEVPGGSAHYGGPS(ph)PEKK_
RECQL5 Phosphorylation S815 -0.400 -0.271 _YTGEEDGAGGHS(ph)PAPPQTEECLR_
RECQL5 Phosphorylation T839 0.366 0.040 _DQGT(ph)PEVQPTPAK_
RPAP2 Ubiquitylation K310 1.272 _LK(gl)ASENSESEYSR_
RPAP2 Ubiquitylation K331 1.424 _SEITLVGISK(gl)K_
RPAP2 Ubiquitylation K332 1.424 _SEITLVGISK(gl)K_
RPRD1A Phosphorylation S156 -0.063 -0.120 _VDENENCSSLGS(ph)PSEPPQTLDLVR_
RPRD1A Phosphorylation S158 -0.243 -0.235 _VDENENCSSLGSPS(ph)EPPQTLDLVR_
RPRD1B Ubiquitylation K11 0.621 _(ac)SSFSESALEK(gl)K_
RPRD1B Ubiquitylation K12 0.419 _(ac)SSFSESALEKK(gl)_
RPRD1B Phosphorylation S132 -0.334 _LSM(ox)EDS(ph)KSPPPK_
RPRD1B Phosphorylation S134 -0.203 0.030 _LSMEDSKS(ph)PPPK_
RPRD1B Phosphorylation S156 -0.063 -0.120 _VDENENCSSLGS(ph)PSEPPQTLDLVR_
RPRD1B Phosphorylation S158 -0.243 -0.235 _VDENENCSSLGSPS(ph)EPPQTLDLVR_
RPRD1B Ubiquitylation K272 -0.212 -0.554 _DVLSEK(gl)EK_
RPRD1B Ubiquitylation K274 -0.212 -0.554 _DVLSEK(gl)EK_


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