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Query: RPRD1B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RPRD1B 1 6.480 -0.280 0.460 0.178 1.395 2.538 -0.102 0.850
RPRD1B 1 6.480 -0.280 0.460 0.234 1.123 2.253 -0.005 0.487

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RPRD1B Ubiquitylation K12 0.419 _(ac)SSFSESALEKK(gl)_
RPRD1B Phosphorylation S134 -0.203 0.030 _LSMEDSKS(ph)PPPK_
RPRD1B Phosphorylation S156 -0.063 -0.120 _VDENENCSSLGS(ph)PSEPPQTLDLVR_
RPRD1B Phosphorylation S158 -0.243 -0.235 _VDENENCSSLGSPS(ph)EPPQTLDLVR_
RPRD1B Ubiquitylation K272 -0.212 -0.554 _DVLSEK(gl)EK_
RPRD1B Ubiquitylation K274 -0.212 -0.554 _DVLSEK(gl)EK_
RPRD1B Ubiquitylation K11 0.621 _(ac)SSFSESALEK(gl)K_
RPRD1B Phosphorylation S132 -0.334 _LSM(ox)EDS(ph)KSPPPK_

Background Information for RPRD1B:


Pubmed-RPRD1B »
Uniprot-RPRD1B »
Biogrid-RPRD1B »
ProteomicsDB-RPRD1B »

Tumorportal-RPRD1B »
COSMIC-RPRD1B »
GenomeRNAi-RPRD1B »
Genecards-RPRD1B


Protein-protein Interactions for RPRD1B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP170P1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEFM Cat. description Hein, Mann, Cell 2015
Category members IP bait RB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF168 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPRD1B Cat. description Hein, Mann, Cell 2015
Category members IP bait SUPT5H Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS4B Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTL6A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LMO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STRAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RPRD1B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RNA_pol_II-bd IPR006903 2.39
Category members CID_dom IPR006569 1.43
Category members ENTH_VHS IPR008942 0.96


Protein complexes (CORUM database) featuring RPRD1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RPRD1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0016591 DNA-directed RNA polymerase II, holoenzyme Database 1.52
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0000993 RNA polymerase II core binding Database 0.91
Category members GO Category GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain Database 0.39
Category members GO Category GO:0010564 regulation of cell cycle process Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0


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