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Query: RECQL5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RECQL5 1 6.633 -0.670 1.270 3.649 0.084 1.224

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RECQL5 Phosphorylation T839 0.366 0.040 _DQGT(ph)PEVQPTPAK_
RECQL5 Phosphorylation S815 -0.400 -0.271 _YTGEEDGAGGHS(ph)PAPPQTEECLR_
RECQL5 Phosphorylation S727 -0.587 -0.527 _GEVPGGSAHYGGPS(ph)PEKK_

Background Information for RECQL5:


Pubmed-RECQL5 »
Uniprot-RECQL5 »
Biogrid-RECQL5 »
ProteomicsDB-RECQL5 »

Tumorportal-RECQL5 »
COSMIC-RECQL5 »
GenomeRNAi-RECQL5 »
Genecards-RECQL5


Protein-protein Interactions for RECQL5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CUL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FOSL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6B Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2F Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2G Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SHOC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DOM3Z Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRINL1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LMO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PITHD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR2E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR2G Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPRD1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RECQL5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members Helicase/UvrB_dom IPR006935 0.78
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members DNA_helicase_ATP-dep_RecQ IPR004589 0.25


Protein complexes (CORUM database) featuring RECQL5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RECQL5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0003678 DNA helicase activity Database 2.22
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016591 DNA-directed RNA polymerase II, holoenzyme Database 1.52
Category members GO Category GO:0032508 DNA duplex unwinding Database 1.24
Category members GO Category GO:0000993 RNA polymerase II core binding Database 0.91
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0051304 chromosome separation Database 0.35
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0006259 DNA metabolic process Database 0
Category members GO Category GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter Database 0


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