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Results for the Category
DNA helicase activity
(GO:0003678)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
MCM2 2 0.740 -0.140 0.552 0.052
MCM2 2 0.740 -0.140 1.288
MCM2 2 0.740 -0.140
MCM6 2 -0.170 -0.180 1.067 0.473 -0.065
ATRX 2 0.050 0.010 0.582 0.629
CHD8 1 -1.310 2.760 -0.896 0.435 0.478 -1.819 -1.191
CHD8 1 -1.310 2.760 -1.168 0.026 0.297
SETX 1 -0.220 1.020 3.162
RECQL5 1 -0.670 1.270 3.649 0.084 1.224
MCM3 1 -1.860 3.650 1.197 0.554 0.207
DNA2 1 1.707
PIF1 1 0.190 0.090
RUVBL1 1 -2.280 5.280 0.726 0.246 0.680 0.325 0.277
RUVBL2 1 -2.210 5.080 0.796 0.479 0.807 0.364 0.491
RECQL 0 -0.890 2.070 -0.132 0.119 -0.395 -0.106 -0.300
DDX11 0 -0.980 0.900
MCM5 0 -0.890 1.090
MCM5 0 -0.890 1.090 0.660 0.490 0.195
MCM4 0 0.700 0.170 0.876 0.344 -0.023 0.237 0.753
C10orf2 0 -0.470 0.220 1.219 0.017
INO80 0 1.190 -1.020 0.414 0.682
SUPV3L1 0 1.500 -0.040 0.342 0.274 0.234 0.059 0.110
WRN 0 -0.320 -0.170 0.180
MCM7 0 -0.260 -0.010 0.361 -0.040
MCM7 0 -0.260 -0.010 0.592
RAD51B 0 -1.570 1.980
RAD54B 0 1.010 -0.510

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATRX Phosphorylation S34 -0.115 -0.055 _LHDFLAHSSEESEETSS(ph)PPR_
ATRX Phosphorylation S92 -0.219 -0.386 _YVES(ph)DDEKPLDDETVNEDASNENSENDITMQSLPK_
ATRX Phosphorylation S313 0.766 0.451 _VYEHTS(ph)RFSPK_
ATRX Phosphorylation S316 0.668 _VYEHTSRFS(ph)PK_
ATRX Ubiquitylation K403 0.759 _SVLADIK(gl)K_
ATRX Ubiquitylation K404 0.759 _SVLADIK(gl)K_
ATRX Phosphorylation S596 0.021 _LTPVSLS(ph)NSPIKGADCQEVPQDKDGYK_
ATRX Phosphorylation S598 -0.157 -0.195 _LTPVSLSNS(ph)PIK_
ATRX Phosphorylation S677 0.048 0.009 _RPTETNPVTSNS(ph)DEECNETVKEK_
ATRX Phosphorylation S819 0.797 0.578 _RQTQSESSNYDS(ph)ELEKEIK_
ATRX Phosphorylation S871 3.829 4.009 _NLKTS(ph)QEGSSDDAER_
ATRX Phosphorylation T887 1.203 1.421 _ET(ph)FSSAEGTVDKDTTIMELR_
ATRX Phosphorylation S889 0.942 _ETFS(ph)SAEGTVDKDTTIMELR_
ATRX Phosphorylation S1061 1.043 0.887 _KDELS(ph)DYAEK_
ATRX Phosphorylation S1527 -0.080 0.235 _EVIEIEDAS(ph)PTKCPITTK_
ATRX Ubiquitylation K2182 -0.315 _QVTK(gl)QSLSFR_
C10orf2 Ubiquitylation K633 -0.146 _NSLTFSIPPK(gl)_
CHD8 Phosphorylation S557 -0.452 _VPVHQHS(ph)PSEPFLEKPVPDM(ox)TQVSGPNAQLVK_
CHD8 Ubiquitylation K1766 0.498 _EQMK(gl)IEAAER_
CHD8 Phosphorylation S1874 -0.088 -0.155 _TPFKDEIDEFANS(ph)PSEDKEESMEIHATGK_
CHD8 Phosphorylation S1978 0.606 0.061 _M(ox)NYM(ox)QNHQAGAPAPSLS(ph)R_
CHD8 Phosphorylation T1993 -1.383 -1.407 _T(ph)ASPLPLRPDAPVEKS(ph)PEETATQVPSLESLTLK_
CHD8 Phosphorylation S1995 -0.690 -1.351 _TAS(ph)PLPLRPDAPVEK_
CHD8 Phosphorylation S2008 -1.339 -1.407 _T(ph)ASPLPLRPDAPVEKS(ph)PEETATQVPSLESLTLK_
CHD8 Phosphorylation S2046 0.427 0.449 _VS(ph)PSDTTPLVSR_
CHD8 Phosphorylation S2519 -0.083 -0.552 _APGYPSS(ph)PVTTASGTTLR_
CHD8 Phosphorylation S2533 -0.792 _RTS(ph)LSAEDAEVTK_
CHD8 Phosphorylation S2559 -0.345 -0.513 _NIPS(ph)PGQLDPDTR_
CHD8 Phosphorylation S2956 0.383 -0.248 _DGETLEGS(ph)DAEESLDK_
DDX11 Ubiquitylation K173 0.779 -0.864 _VQLK(gl)YAAK_
DDX11 Ubiquitylation K520 -0.747 _YCEK(gl)SMISR_
DDX11 Ubiquitylation K830 -1.499 _SAELQEK(gl)MAYLDQTLPR_
DNA2 Ubiquitylation K589 -1.040 _LMENTFVSK(gl)K_
DNA2 Ubiquitylation K590 -1.040 _LMENTFVSK(gl)K_
DNA2 Ubiquitylation K811 -0.860 _ALGMSESLFK(gl)R_
MCM2 Phosphorylation S4 0.060 -0.102 _(ac)AES(ph)SESFTM(ox)ASS(ph)PAQR_
MCM2 Phosphorylation S5 0.653 0.313 _(ac)AESS(ph)ESFTMASSPAQR_
MCM2 Phosphorylation T9 0.528 0.894 _(ac)AESSESFT(ph)MASSPAQR_
MCM2 Phosphorylation S12 0.027 0.508 _AESSESFTMAS(ph)SPAQR_
MCM2 Phosphorylation S13 0.595 0.841 _(ac)AESSESFTMASS(ph)PAQR_
MCM2 Phosphorylation S26 0.334 0.204 _GNDPLTS(ph)SPGR_
MCM2 Phosphorylation S27 0.076 0.378 _GNDPLTSS(ph)PGR_
MCM2 Phosphorylation S40 0.648 1.028 _TDALTS(ph)SPGR_
MCM2 Phosphorylation S41 0.613 0.869 _RTDALTSS(ph)PGR_
MCM2 Phosphorylation T106 2.035 2.162 _AIPELDAYEAEGLALDDEDVEELT(ph)ASQR_
MCM2 Phosphorylation S108 1.832 2.212 _AIPELDAYEAEGLALDDEDVEELTAS(ph)QR_
MCM2 Phosphorylation S139 0.404 0.482 _GLLYDS(ph)DEEDEERPAR_
MCM2 Ubiquitylation K205 0.225 0.747 _ISDMCK(gl)ENR_
MCM2 Ubiquitylation K365 -0.341 0.407 _IQESPGK(gl)VAAGR_
MCM2 Ubiquitylation K450 0.216 0.470 _MITSLSK(gl)DQQIGEK_
MCM2 Ubiquitylation K946 -0.032 _FSHDLK(gl)R_
MCM3 Ubiquitylation K198 -0.209 -1.171 _SVHYCPATKK(gl)_
MCM3 Phosphorylation S205 0.571 -0.326 _RYS(ph)DLTTLVAFPSSSVYPTK_
MCM3 Phosphorylation T209 0.700 0.517 _RYSDLTT(ph)LVAFPSSSVYPTK_
MCM3 Ubiquitylation K293 0.760 -0.751 _K(gl)GGYTSGTFR_
MCM3 Ubiquitylation K311 0.886 1.210 _TVLIACNVK(gl)QMSK_
MCM3 Ubiquitylation K480 0.706 0.010 _VTIAK(gl)AGIHAR_
MCM3 Ubiquitylation K508 -0.031 _YDQYK(gl)TPMENIGLQDSLLSR_
MCM3 Phosphorylation S713 0.697 _S(ph)EDESETEDEEEKSQEDQEQK_
MCM3 Phosphorylation S717 0.009 0.302 _SEDES(ph)ETEDEEEK_
MCM3 Phosphorylation S756 -0.581 -0.455 _DGDSYDPYDFS(ph)DTEEEMPQVHTPK_
MCM3 Phosphorylation T758 -0.622 _DGDSYDPYDFS(ph)DTEEEM(ox)PQVHTPK_
MCM3 Phosphorylation T767 -0.699 -0.088 _DGDSYDPYDFSDTEEEMPQVHT(ph)PK_
MCM3 Ubiquitylation K777 -0.521 _TADSQETK(gl)ESQKVELSESR_
MCM3 Ubiquitylation K781 -0.081 -0.408 _ESQK(gl)VELSESR_
MCM4 Phosphorylation S26 -0.380 0.511 _ATPAQTPRS(ph)EDAR_
MCM4 Phosphorylation S131 0.424 0.474 _GLQVDLQS(ph)DGAAAEDIVASEQSLGQK_
MCM4 Ubiquitylation K220 -0.271 0.326 _SFDK(gl)NLYR_
MCM4 Phosphorylation S326 0.118 0.226 _IAEPS(ph)VCGR_
MCM4 Ubiquitylation K353 -0.534 _SLFSDKQMIK(gl)_
MCM4 Ubiquitylation K409 0.140 -0.445 _VSNVK(gl)SVYK_
MCM4 Ubiquitylation K450 -0.607 _VELLK(gl)ELSR_
MCM4 Ubiquitylation K478 -0.439 _LASALAPSIYEHEDIKK(gl)_
MCM4 Ubiquitylation K536 -0.941 -0.853 _GQYTSGK(gl)GSSAVGLTAYVMKDPETR_
MCM4 Ubiquitylation K549 -0.023 -0.647 _GSSAVGLTAYVMK(gl)DPETR_
MCM4 Ubiquitylation K628 -1.124 -3.224 _TSVLAAANPIESQWNPKK(gl)_
MCM4 Ubiquitylation K746 -0.079 _LAEAHAK(gl)VR_
MCM4 Ubiquitylation K752 -0.885 -0.700 _LSNK(gl)VEAIDVEEAK(gl)R_
MCM4 Ubiquitylation K762 -0.483 -0.551 _VEAIDVEEAK(gl)R_
MCM4 Ubiquitylation K770 -0.963 -0.688 _EALK(gl)QSATDPR_
MCM4 Ubiquitylation K814 -1.087 _GK(gl)TPALK_
MCM4 Ubiquitylation K858 0.042 _ALADDDFLTVTGK(gl)TVR_
MCM5 Phosphorylation S2 0.212 0.649 _S(ph)GFDDPGIFYSDSFGGDAQADEGQAR_
MCM5 Phosphorylation S14 1.191 _(ac)SGFDDPGIFYSDS(ph)FGGDAQADEGQAR_
MCM5 Ubiquitylation K392 -0.464 -0.556 _SQLLK(gl)FVEK_
MCM5 Ubiquitylation K583 0.060 -0.670 _LSAEAAEKLK(gl)_
MCM6 Phosphorylation S13 4.283 4.775 _(ac)M(ox)DLAAAAEPGAGS(ph)QHLEVRDEVAEK_
MCM6 Ubiquitylation K95 0.656 _ALK(gl)TFVK_
MCM6 Ubiquitylation K197 0.461 0.797 _FLLDTNK(gl)SR_
MCM6 Ubiquitylation K332 0.272 0.709 _NQMTVK(gl)EWEK_
MCM6 Ubiquitylation K422 0.854 _AVYTSGK(gl)ASSAAGLTAAVVR_
MCM6 Ubiquitylation K490 0.630 _AGVK(gl)ATLNAR_
MCM6 Ubiquitylation K517 0.150 -0.502 _SLK(gl)QNINLSAPIMSR_
MCM6 Ubiquitylation K611 1.032 0.016 _DGSGVTK(gl)SSWR_
MCM6 Ubiquitylation K643 -0.198 _MHCCDEVQPK(gl)HVK_
MCM6 Ubiquitylation K654 0.288 -0.028 _LLNK(gl)SIIR_
MCM6 Ubiquitylation K744 -0.152 -0.415 _KVEEEEDESALK(gl)R_
MCM6 Phosphorylation S758 0.528 2.700 _EIES(ph)EIDSEEELINK_
MCM6 Phosphorylation S762 1.561 1.325 _EIESEIDS(ph)EEELINK_
MCM6 Ubiquitylation K775 0.748 _IIEK(gl)VIHR_
MCM7 Ubiquitylation K4 -1.164 _(ac)ALK(gl)DYALEKEK_
MCM7 Ubiquitylation K10 -0.334 -1.453 _(ac)ALKDYALEK(gl)EK_
MCM7 Ubiquitylation K12 -1.492 _DYALEK(gl)EK_
MCM7 Ubiquitylation K28 -0.102 -0.861 _FLQEFYQDDELGK(gl)K_
MCM7 Ubiquitylation K29 -1.023 -0.094 _FLQEFYQDDELGKK(gl)QFK_
MCM7 Ubiquitylation K32 0.146 -0.970 _QFK(gl)YGNQLVR_
MCM7 Ubiquitylation K89 -1.906 -1.328 _LFADAVQELLPQYK(gl)ER_
MCM7 Phosphorylation S121 0.902 0.509 _S(ph)PQNQYPAELMR_
MCM7 Ubiquitylation K145 -2.703 _RFELYFQGPSSNK(gl)PR_
MCM7 Ubiquitylation K159 0.038 -0.495 _ADSVGK(gl)LVTVR_
MCM7 Ubiquitylation K231 -0.965 _FIK(gl)FQEMK_
MCM7 Ubiquitylation K236 -1.769 _FQEMK(gl)MQEHSDQVPVGNIPR_
MCM7 Ubiquitylation K352 -1.468 _LAASIAPEIYGHEDVKK(gl)_
MCM7 Ubiquitylation K557 -2.556 -2.098 _QPPSQFEPLDMK(gl)LMR_
MCM7 Ubiquitylation K596 -0.751 -0.539 _REAWASK(gl)DATYTSAR_
MCM7 Ubiquitylation K627 -0.965 -0.588 _MVDVVEK(gl)EDVNEAIR_
MCM7 Ubiquitylation K641 -0.836 -0.945 _LMEMSK(gl)DSLLGDKGQTAR_
MCM7 Ubiquitylation K648 -0.422 -0.441 _DSLLGDK(gl)GQTAR_
PIF1 Phosphorylation S151 4.353 _DFVTIS(ph)PVQPEER_
RAD51B Ubiquitylation K71 -0.262 _MQTAYGIK(gl)AQR_
RAD54B Phosphorylation S14 -0.406 _SAAPSQLQGNS(ph)FK_
RECQL Ubiquitylation K38 0.847 1.387 _QQELIQK(gl)K_
RECQL5 Phosphorylation S727 -0.587 -0.527 _GEVPGGSAHYGGPS(ph)PEKK_
RECQL5 Phosphorylation S815 -0.400 -0.271 _YTGEEDGAGGHS(ph)PAPPQTEECLR_
RECQL5 Phosphorylation T839 0.366 0.040 _DQGT(ph)PEVQPTPAK_
RUVBL1 Ubiquitylation K7 0.148 0.466 _MKIEEVK(gl)STTK_
RUVBL1 Ubiquitylation K171 0.030 -0.502 _QLK(gl)LDPSIFESLQK_
RUVBL1 Ubiquitylation K201 0.095 _VEAGDVIYIEANSGAVK(gl)R_
RUVBL2 Ubiquitylation K9 -0.203 -0.294 _(ac)ATVTATTK(gl)VPEIRDVTR_
RUVBL2 Ubiquitylation K160 0.331 _VGK(gl)LTLK_
RUVBL2 Ubiquitylation K186 -0.554 _DK(gl)VQAGDVITIDK_
RUVBL2 Ubiquitylation K234 -0.191 -0.742 _FVQCPDGELQK(gl)R_
RUVBL2 Ubiquitylation K365 -0.355 -0.601 _LLIVSTTPYSEK(gl)DTK_
RUVBL2 Ubiquitylation K368 -0.345 _LLIVSTTPYSEKDTK(gl)QILR_
RUVBL2 Ubiquitylation K417 -1.196 _K(gl)GTEVQVDDIK(gl)R_
RUVBL2 Ubiquitylation K427 0.479 0.403 _K(gl)GTEVQVDDIK(gl)R_
SETX Ubiquitylation K621 -0.836 -1.466 _ISPASYNK(gl)EESEQMGK_
SETX Ubiquitylation K694 -0.746 -0.855 _QSSK(gl)NIFTER_
SETX Ubiquitylation K706 -0.633 -0.833 _AEDQIK(gl)ISTR_
SETX Ubiquitylation K768 -0.451 -2.400 _VSTSNEDFSLK(gl)DDALAK_
SETX Ubiquitylation K908 -1.099 _ELIPFTEMTNASEK(gl)K_
SETX Ubiquitylation K909 -1.099 _ELIPFTEMTNASEK(gl)K_
SETX Phosphorylation S947 -0.622 -1.829 _EQAPDIS(ph)PK_
SUPV3L1 Phosphorylation S725 -0.599 -0.964 _ATEPPS(ph)PDAGELSLASR_
WRN Ubiquitylation K134 0.717 _MLLENKAVK(gl)_
WRN Phosphorylation S1133 0.363 0.023 _SIMVQS(ph)PEK_


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