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Query: SETX

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SETX 1 0.447 -0.220 1.020 3.162

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SETX Ubiquitylation K706 -0.633 -0.833 _AEDQIK(gl)ISTR_
SETX Ubiquitylation K694 -0.746 -0.855 _QSSK(gl)NIFTER_
SETX Ubiquitylation K908 -1.099 _ELIPFTEMTNASEK(gl)K_
SETX Ubiquitylation K909 -1.099 _ELIPFTEMTNASEK(gl)K_
SETX Ubiquitylation K621 -0.836 -1.466 _ISPASYNK(gl)EESEQMGK_
SETX Phosphorylation S947 -0.622 -1.829 _EQAPDIS(ph)PK_
SETX Ubiquitylation K768 -0.451 -2.400 _VSTSNEDFSLK(gl)DDALAK_

Background Information for SETX:


Pubmed-SETX »
Uniprot-SETX »
Biogrid-SETX »
ProteomicsDB-SETX »

Tumorportal-SETX »
COSMIC-SETX »
GenomeRNAi-SETX »
Genecards-SETX


Protein-protein Interactions for SETX
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLU Cat. description Hein, Mann, Cell 2015
Category members IP bait CNTROB Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF7 Cat. description Hein, Mann, Cell 2015
Category members IP bait NHSL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2F Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2G Cat. description Hein, Mann, Cell 2015
Category members IP bait RPRD1B Cat. description Hein, Mann, Cell 2015
Category members IP bait SUPT5H Cat. description Hein, Mann, Cell 2015
Category members IP bait APBB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMTD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FZD10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISLR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK8IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEUROG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNKD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SETMAR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SETX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWA5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SETX
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members UvrD-like_ATP-bd IPR014016 0.05


Protein complexes (CORUM database) featuring SETX
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SETX
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members GO Category GO:0003678 DNA helicase activity Database 2.22
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0032508 DNA duplex unwinding Database 1.24
Category members GO Category GO:0006369 termination of RNA polymerase II transcription Database 0.87
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0007623 circadian rhythm Database 0


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