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Query: RECQL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RECQL 0 3.490 -0.890 2.070 -0.132 0.119 -0.395 -0.106 -0.300

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RECQL Ubiquitylation K38 0.847 1.387 _QQELIQK(gl)K_

Background Information for RECQL:


Pubmed-RECQL »
Uniprot-RECQL »
Biogrid-RECQL »
ProteomicsDB-RECQL »

Tumorportal-RECQL »
COSMIC-RECQL »
GenomeRNAi-RECQL »
Genecards-RECQL


Protein-protein Interactions for RECQL
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait CYP1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RECQL
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members DNA_helicase_ATP-dep_RecQ IPR004589 0.25
Category members RQC_domain IPR018982 0.11


Protein complexes (CORUM database) featuring RECQL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RECQL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004003 ATP-dependent DNA helicase activity Database 4.66
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003678 DNA helicase activity Database 2.22
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0032508 DNA duplex unwinding Database 1.24
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0043140 ATP-dependent 3'-5' DNA helicase activity Database 0.25
Category members GO Category GO:0036310 annealing helicase activity Database 0.01
Category members GO Category GO:0000733 DNA strand renaturation Database 0


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