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Query: C10ORF2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
C10orf2 0 1.310 -0.470 0.220 1.219 0.017

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
C10orf2 Ubiquitylation K633 -0.146 _NSLTFSIPPK(gl)_

Background Information for C10orf2:


Pubmed-C10orf2 »
Uniprot-C10orf2 »
Biogrid-C10orf2 »
ProteomicsDB-C10orf2 »

Tumorportal-C10orf2 »
COSMIC-C10orf2 »
GenomeRNAi-C10orf2 »
Genecards-C10orf2


Protein-protein Interactions for C10orf2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C10orf2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC111 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEXIM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBMX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRA2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF169 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF263 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in C10orf2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members DNA_helicase_DnaB-like_C IPR007694 0
Category members Circ_KaiC/RadA IPR014774 0


Protein complexes (CORUM database) featuring C10orf2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring C10orf2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0003678 DNA helicase activity Database 2.22
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61
Category members GO Category GO:0006268 DNA unwinding involved in DNA replication Database 0.19
Category members GO Category GO:0043139 5'-3' DNA helicase activity Database 0.17
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0006390 transcription from mitochondrial promoter Database 0.07
Category members Disease phenotype Autosomal_dominant_progressive_external_ophthalmoplegia Autosomal dominant progressive external ophthalmoplegia Database 0
Category members Disease phenotype PROGRESSIVE_EXTERNAL_OPHTHALMOPLEGIA_WITH_MITOCHONDRIAL_DNA_DELETIONS PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS Database 0
Category members Disease phenotype Sensory_ataxic_neuropathy_-_dysarthria_-_ophthalmoparesis Sensory ataxic neuropathy - dysarthria - ophthalmoparesis Database 0
Category members Disease phenotype SENSORY_ATAXIC_NEUROPATHY_DYSARTHRIA_AND_OPHTHALMOPARESIS SENSORY ATAXIC NEUROPATHY DYSARTHRIA AND OPHTHALMOPARESIS Database 0
Category members GO Category GO:0002020 protease binding Database 0
Category members GO Category GO:0006264 mitochondrial DNA replication Database 0
Category members GO Category GO:0034214 protein hexamerization Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0


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