Results for the Category
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS
(PROGRESSIVE_EXTERNAL_OPHTHALMOPLEGIA_WITH_MITOCHONDRIAL_DNA_DELETIONS)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| RRM2B | 1 | -0.160 | -0.120 | |||||
| DNA2 | 1 | 1.707 | ||||||
| SLC25A4 | 1 | 0.410 | -0.470 | |||||
| SLC25A4 | 1 | 0.410 | -0.470 | 0.878 | 0.610 | |||
| SLC25A6 | 1 | 0.700 | -1.050 | 0.334 | 2.424 | |||
| C10orf2 | 0 | -0.470 | 0.220 | 1.219 | 0.017 | |||
| POLG | 0 | 1.190 | -0.550 | -1.116 | -0.380 | 0.081 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| C10orf2 | Ubiquitylation | K633 | -0.146 | _NSLTFSIPPK(gl)_ | |
| DNA2 | Ubiquitylation | K589 | -1.040 | _LMENTFVSK(gl)K_ | |
| DNA2 | Ubiquitylation | K590 | -1.040 | _LMENTFVSK(gl)K_ | |
| DNA2 | Ubiquitylation | K811 | -0.860 | _ALGMSESLFK(gl)R_ | |
| POLG | Ubiquitylation | K371 | -2.064 | _LYVGGPPLEK(gl)EPR_ | |
| POLG | Ubiquitylation | K990 | -1.545 | _AQQMYAATK(gl)GLR_ | |
| RRM2B | Ubiquitylation | K424 | 2.394 | -0.588 | _TNFFEK(gl)R_ |
| SLC25A4 | Ubiquitylation | K52 | 0.200 | _QYK(gl)GIIDCVVR_ | |
| SLC25A6 | Ubiquitylation | K88 | -2.095 | _IPK(gl)EQGVLSFWR_ | |
| SLC25A6 | Ubiquitylation | K172 | -0.787 | 0.875 | _LAADVGK(gl)SGTER_ |
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