bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: POLG

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
POLG 0 -2.960 1.190 -0.550 -1.116 -0.380 0.081

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
POLG Ubiquitylation K990 -1.545 _AQQMYAATK(gl)GLR_
POLG Ubiquitylation K371 -2.064 _LYVGGPPLEK(gl)EPR_

Background Information for POLG:


Pubmed-POLG »
Uniprot-POLG »
Biogrid-POLG »
ProteomicsDB-POLG »

Tumorportal-POLG »
COSMIC-POLG »
GenomeRNAi-POLG »
Genecards-POLG


Protein-protein Interactions for POLG
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait POLG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEPT9 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACSM5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BPNT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C17orf90 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C20orf72 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NIT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OTC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YBEY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in POLG
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DNA-dir_DNA_pol_A_palm_dom IPR001098 0
Category members RNaseH-like_dom IPR012337 0


Protein complexes (CORUM database) featuring POLG
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring POLG
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61
Category members GO Category GO:0006287 base-excision repair, gap-filling Database 0.48
Category members GO Category GO:0006261 DNA-dependent DNA replication Database 0.48
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0008219 cell death Database 0.08
Category members Disease phenotype Mitochondrial_neurogastrointestinal_encephalomyopathy Mitochondrial neurogastrointestinal encephalomyopathy Database 0.07
Category members Disease phenotype Autosomal_dominant_progressive_external_ophthalmoplegia Autosomal dominant progressive external ophthalmoplegia Database 0
Category members Disease phenotype Leigh_syndrome Leigh syndrome Database 0
Category members Disease phenotype PROGRESSIVE_EXTERNAL_OPHTHALMOPLEGIA_WITH_MITOCHONDRIAL_DNA_DELETIONS PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS Database 0
Category members Disease phenotype Sensory_ataxic_neuropathy_-_dysarthria_-_ophthalmoparesis Sensory ataxic neuropathy - dysarthria - ophthalmoparesis Database 0
Category members Disease phenotype SENSORY_ATAXIC_NEUROPATHY_DYSARTHRIA_AND_OPHTHALMOPARESIS SENSORY ATAXIC NEUROPATHY DYSARTHRIA AND OPHTHALMOPARESIS Database 0
Category members GO Category GO:0002020 protease binding Database 0
Category members GO Category GO:0003887 DNA-directed DNA polymerase activity Database 0
Category members GO Category GO:0004527 exonuclease activity Database 0
Category members GO Category GO:0005760 gamma DNA polymerase complex Database 0
Category members GO Category GO:0006259 DNA metabolic process Database 0
Category members GO Category GO:0006264 mitochondrial DNA replication Database 0
Category members GO Category GO:0007568 aging Database 0


.

© Copyright Svejstrup Laboratory 2015