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Query: SLC25A6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC25A6 1 2.513 0.700 -1.050 0.334 2.424

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC25A6 Ubiquitylation K172 -0.787 0.875 _LAADVGK(gl)SGTER_
SLC25A6 Ubiquitylation K88 -2.095 _IPK(gl)EQGVLSFWR_

Background Information for SLC25A6:


Pubmed-SLC25A6 »
Uniprot-SLC25A6 »
Biogrid-SLC25A6 »
ProteomicsDB-SLC25A6 »

Tumorportal-SLC25A6 »
COSMIC-SLC25A6 »
GenomeRNAi-SLC25A6 »
Genecards-SLC25A6


Protein-protein Interactions for SLC25A6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG3 Cat. description Hein, Mann, Cell 2015
Category members IP bait HAX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR3E Cat. description Hein, Mann, Cell 2015
Category members IP bait SCAF11 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD79B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CNDP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ERGIC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM131B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM187B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISLR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDCD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMEL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPACA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THBS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMCO3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOMM22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC25A6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aden_trnslctor IPR002113 0.38
Category members Mit_uncoupling IPR002030 0
Category members Mit_carrier IPR002067 0
Category members Mitochondrial_sb/sol_carrier IPR018108 0
Category members Mt_carrier_dom IPR023395 0


Protein complexes (CORUM database) featuring SLC25A6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC25A6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0019058 viral life cycle Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_1206 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS 0 6.87
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 0 0.33
Category members GO Category GO:0006112 energy reserve metabolic process Database 0.21
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0006626 protein targeting to mitochondrion Database 0.11
Category members Pathway Pathway_270 REACTOME_REGULATION_OF_INSULIN_SECRETION 0 0.09
Category members GO Category GO:0050796 regulation of insulin secretion Database 0.06
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members Pathway Pathway_48 BIOCARTA_ETC_PATHWAY 0 0
Category members GO Category GO:0005215 transporter activity Database 0
Category members GO Category GO:0005744 mitochondrial inner membrane presequence translocase complex Database 0
Category members GO Category GO:0046732 active induction of host immune response by virus Database 0


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