bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: SLC25A4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC25A4 1 4.001 0.410 -0.470
SLC25A4 1 4.001 0.410 -0.470 0.878 0.610
SLC25A4 1 4.001 0.410 -0.470 0.334 2.424

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC25A4 Ubiquitylation K172 -0.787 0.875 _LAADVGK(gl)SGTER_
SLC25A4 Ubiquitylation K52 0.200 _QYK(gl)GIIDCVVR_
SLC25A4 Ubiquitylation K88 -2.095 _IPK(gl)EQGVLSFWR_

Background Information for SLC25A4:


Pubmed-SLC25A4 »
Uniprot-SLC25A4 »
Biogrid-SLC25A4 »
ProteomicsDB-SLC25A4 »

Tumorportal-SLC25A4 »
COSMIC-SLC25A4 »
GenomeRNAi-SLC25A4 »
Genecards-SLC25A4


Protein-protein Interactions for SLC25A4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIAA1430 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCNT Cat. description Hein, Mann, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISLR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB2A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC25A4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aden_trnslctor IPR002113 0.38
Category members Mit_uncoupling IPR002030 0
Category members Mit_carrier IPR002067 0
Category members Mitochondrial_sb/sol_carrier IPR018108 0
Category members Mt_carrier_dom IPR023395 0


Protein complexes (CORUM database) featuring SLC25A4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC25A4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_1206 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS 0 6.87
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 0 0.33
Category members GO Category GO:0006112 energy reserve metabolic process Database 0.21
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members Pathway Pathway_270 REACTOME_REGULATION_OF_INSULIN_SECRETION 0 0.09
Category members GO Category GO:0050796 regulation of insulin secretion Database 0.06
Category members GO Category GO:0015853 adenine transport Database 0.03
Category members GO Category GO:0008637 apoptotic mitochondrial changes Database 0.01
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members Pathway Pathway_48 BIOCARTA_ETC_PATHWAY 0 0
Category members Disease phenotype Autosomal_dominant_progressive_external_ophthalmoplegia Autosomal dominant progressive external ophthalmoplegia Database 0
Category members Disease phenotype PROGRESSIVE_EXTERNAL_OPHTHALMOPLEGIA_WITH_MITOCHONDRIAL_DNA_DELETIONS PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS Database 0
Category members GO Category GO:0000002 mitochondrial genome maintenance Database 0
Category members GO Category GO:0006091 generation of precursor metabolites and energy Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0015207 adenine transmembrane transporter activity Database 0
Category members GO Category GO:0060547 negative regulation of necrotic cell death Database 0


.

© Copyright Svejstrup Laboratory 2015