bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Category

Results for the Category
apoptotic mitochondrial changes
(GO:0008637)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PPIE 2 -2.470 3.680 2.485 0.018 1.294 0.696
ATP2A1 2 -1.020 1.690 0.192 -0.474 0.081 0.297
PPP2CB 1 2.210 -0.980 0.194 0.044 0.215
PPP2CB 1 2.210 -0.980 0.650 1.189
SOD2 1 -0.340 0.140 2.161 -0.330
SLC25A4 1 0.410 -0.470
SLC25A4 1 0.410 -0.470 0.878 0.610
SLC25A6 1 0.700 -1.050 0.334 2.424
NDUFS1 0 -0.550 0.770 0.388 -0.330 -1.498 0.368 0.186
GCLM 0 0.680 -0.230
AIFM2 0 -1.340 1.620
BAX 0 1.590 -1.170 0.811 0.359
MAP3K1 0 0.750 -1.270
DAP3 0 -0.610 0.800 0.004 -0.279 0.110 -0.244 -0.227
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
MCL1 0 1.740 -0.780 -0.419
JTB 0 0.440 -0.790
CDKN2A 0 -0.080 -0.260 -0.556 -1.080 -3.270 -1.110
HK2 0 0.400 0.360 -0.317 0.133 -0.115
BCL2L1 0
BCL2 0 0.910 -0.740

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AIFM2 Ubiquitylation K193 0.976 0.037 _QEVK(gl)EILLR_
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
ATP2A1 Ubiquitylation K169 2.444 3.235 _LTSIK(gl)STTLR_
ATP2A1 Ubiquitylation K436 2.681 _GVYEK(gl)VGEATETALTCLVEK_
ATP2A1 Ubiquitylation K460 0.597 2.302 _MNVFDTELK(gl)GLSK_
ATP2A1 Ubiquitylation K464 1.160 3.034 _GLSK(gl)IER_
ATP2A1 Ubiquitylation K476 1.817 3.302 _ANACNSVIK(gl)QLMK_
ATP2A1 Ubiquitylation K480 2.106 _ANACNSVIKQLMK(gl)_
ATP2A1 Ubiquitylation K492 0.229 _K(gl)SMSVYCTPNKPSR_
ATP2A1 Ubiquitylation K502 -0.998 1.220 _SMSVYCTPNK(gl)PSR_
ATP2A1 Ubiquitylation K510 1.498 2.485 _TSMSK(gl)MFVK_
ATP2A1 Ubiquitylation K514 1.598 2.466 _MFVK(gl)GAPEGVIDR_
ATP2A1 Ubiquitylation K533 1.659 2.743 _VGSTK(gl)VPMTSGVK_
ATP2A1 Ubiquitylation K541 2.787 _VPMTSGVK(gl)QK_
ATP2A1 Ubiquitylation K543 1.447 3.874 _QK(gl)IMSVIR_
ATP2A1 Ubiquitylation K611 5.174 4.269 _IEVASSVK(gl)LCR_
ATP2A1 Ubiquitylation K628 0.545 2.714 _VIMITGDNK(gl)GTAVAICR_
ATP2A1 Ubiquitylation K650 1.861 2.614 _IGIFGQDEDVTSK(gl)AFTGR_
ATP2A1 Phosphorylation S663 0.605 0.621 _EFDELNPS(ph)AQR_
ATP2A1 Ubiquitylation K712 2.111 _K(gl)AEIGIAMGSGTAVAK_
ATP2A1 Ubiquitylation K757 2.081 3.431 _AIYNNMK(gl)QFIR_
ATP2A1 Ubiquitylation K995 -1.164 1.549 _NYLEPGK(gl)ECVQPATK_
BAX Ubiquitylation K57 -1.174 _MGGEAPELALDPVPQDASTK(gl)K_
BAX Ubiquitylation K58 -1.718 -1.174 _MGGEAPELALDPVPQDASTKK(gl)_
BAX Ubiquitylation K64 0.708 1.306 _LSECLK(gl)R_
BCL2 Ubiquitylation K22 1.480 _YIHYK(gl)LSQR_
BCL2L1 Ubiquitylation K87 0.026 _EVIPMAAVK(gl)QALR_
DAP3 Ubiquitylation K175 -0.019 _DLLQSSYNK(gl)QR_
GCLM Ubiquitylation K90 -0.531 -0.229 _INPDEREEMK(gl)VSAK_
HK2 Ubiquitylation K346 -0.340 _DISDIEGEK(gl)DGIRK_
HK2 Ubiquitylation K419 0.385 _STIGVDGSVYKK(gl)_
HK2 Ubiquitylation K451 -0.118 _SEDGSGK(gl)GAAMVTAVAYR_
JTB Ubiquitylation K69 -1.118 _AK(gl)TTPECGPTGYVEK_
JTB Ubiquitylation K82 -0.558 _TTPECGPTGYVEK(gl)ITCSSSK_
JTB Ubiquitylation K94 -0.231 _NEFK(gl)SCR_
MAP3K1 Phosphorylation S292 0.209 _RAPS(ph)PDGFSPYSPEETNR_
MAP3K1 Phosphorylation S506 1.427 _SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1 Phosphorylation S507 1.436 _SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1 Phosphorylation S923 0.127 -0.120 _LSAS(ph)SEDISER_
MCL1 Ubiquitylation K40 -0.321 _LLATEK(gl)EASAR_
MCL1 Phosphorylation T163 -1.997 -1.027 _RPAVLPLLELVGESGNNTSTDGSLPST(ph)PPPAEEEEDELYR_
MCL1 Ubiquitylation K194 -1.646 -1.025 _EQATGAK(gl)DTK(gl)PMGR_
MCL1 Ubiquitylation K197 -1.782 -1.165 _EQATGAK(gl)DTK(gl)PMGR_
MCL1 Ubiquitylation K308 -0.687 0.011 _DWLVK(gl)QR_
NDUFS1 Ubiquitylation K298 -1.134 _FAYDGLK(gl)R_
PPIE Ubiquitylation K190 -0.831 _KIESFGSK(gl)SGR_
PPP2CB Ubiquitylation K4 -0.788 -0.378 _(ac)MDDK(gl)AFTK_
PPP2CB Ubiquitylation K4 -0.450 -0.016 _(ac)M(ox)DEK(gl)VFTK_
PPP2CB Ubiquitylation K8 -0.522 _VFTK(gl)ELDQWIEQLNECK_
PPP2CB Ubiquitylation K21 -1.370 _ELDQWVEQLNECK(gl)QLNENQVR_
PPP2CB Ubiquitylation K21 -1.106 _ELDQWIEQLNECK(gl)QLSESQVK_
PPP2CB Ubiquitylation K29 0.211 0.122 _QLSESQVK(gl)SLCEK_
PPP2CB Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CB Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CB Ubiquitylation K41 -0.049 0.003 _EILTK(gl)ESNVQEVR_
PPP2CB Ubiquitylation K74 -0.316 -0.316 _IGGK(gl)SPDTNYLFMGDYVDR_
SLC25A4 Ubiquitylation K52 0.200 _QYK(gl)GIIDCVVR_
SLC25A6 Ubiquitylation K88 -2.095 _IPK(gl)EQGVLSFWR_
SLC25A6 Ubiquitylation K172 -0.787 0.875 _LAADVGK(gl)SGTER_


.

© Copyright Svejstrup Laboratory 2015