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Query: DDX11

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DDX11 0 0.933 -0.980 0.900

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DDX11 Ubiquitylation K520 -0.747 _YCEK(gl)SMISR_
DDX11 Ubiquitylation K173 0.779 -0.864 _VQLK(gl)YAAK_
DDX11 Ubiquitylation K830 -1.499 _SAELQEK(gl)MAYLDQTLPR_

Background Information for DDX11:


Pubmed-DDX11 »
Uniprot-DDX11 »
Biogrid-DDX11 »
ProteomicsDB-DDX11 »

Tumorportal-DDX11 »
COSMIC-DDX11 »
GenomeRNAi-DDX11 »
Genecards-DDX11


Protein-protein Interactions for DDX11
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AVIL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM46A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FUZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GGT7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IARS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KBTBD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPRL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAUR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THBS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOMM22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDFY3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YBEY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DDX11
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase-like_DEXD_c2 IPR006554 0.06
Category members ATP-dep_Helicase_C IPR006555 0.06
Category members DEAD_2 IPR010614 0.06
Category members DNA_helicase_DNA-repair_Rad3 IPR013020 0.06
Category members Helic_SF1/SF2_ATP-bd_DinG/Rad3 IPR014013 0.06


Protein complexes (CORUM database) featuring DDX11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DDX11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004003 ATP-dependent DNA helicase activity Database 4.66
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0008094 DNA-dependent ATPase activity Database 2.31
Category members GO Category GO:0003678 DNA helicase activity Database 2.22
Category members GO Category GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Database 1.64
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members GO Category GO:0032508 DNA duplex unwinding Database 1.24
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0007062 sister chromatid cohesion Database 0.69
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0030496 midbody Database 0.39
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members Pathway Pathway_148 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S 0 0.11
Category members GO Category GO:0006139 nucleobase-containing compound metabolic process Database 0.08
Category members GO Category GO:0016817 hydrolase activity, acting on acid anhydrides Database 0.06
Category members GO Category GO:0000070 mitotic sister chromatid segregation Database 0
Category members GO Category GO:0000084 mitotic S phase Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051539 4 iron, 4 sulfur cluster binding Database 0


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