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DNA-dependent ATPase activity
(GO:0008094)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ERCC6 4 -1.310 2.800 5.118 1.227 2.135
ERCC6 4 0.480 0.030 5.118 1.227 2.135
ERCC6 4 -1.310 2.800 0.074 0.258
ERCC6 4 0.480 0.030 0.074 0.258
GTF2H1 3 -0.470 0.340 0.260 2.656 2.859 1.092 0.966
SMARCA1 2 0.820 0.230 1.940 0.165 0.532 1.513 0.625
ERCC2 2 -0.590 1.060 -0.491 1.066
MSH6 2 -0.410 0.140 -0.115 0.232 0.645 0.407 0.101
ERCC3 2 -1.110 1.490 2.619 2.418 0.499
MSH2 1 -0.130 0.010 0.224 0.457 0.838 0.840 0.366
CHD8 1 -1.310 2.760 -0.896 0.435 0.478 -1.819 -1.191
CHD8 1 -1.310 2.760 -1.168 0.026 0.297
TOP2A 1 -1.940 3.540
TOP2A 1 -1.940 3.540 -1.993 0.211 0.211
SMARCAL1 1 -1.220 1.410 1.748
RBBP4 1 2.110 -1.240 0.533 -0.610 0.648
DDX11 0 -0.980 0.900
MNAT1 0 -0.030 -0.100 0.666
RAD51 0 -1.260 1.920
SMARCA2 0 -0.270 0.240 -0.431 -0.133 0.253 0.069 -0.280
RAD51C 0 0.400 0.260
GTF2H3 0 -0.020 0.680 1.408 0.908
MSH3 0 0.890 -0.360 -0.771 0.719 0.629 0.421 0.240
TTF2 0 -1.140 2.160 -0.431 0.525 0.080
XRCC3 0 0.420 -0.620
SMARCA4 0 -0.810 1.520 0.629 -0.158 0.141 0.337 0.333
CCNH 0 1.480 -0.550
RAD51B 0 -1.570 1.980
MYO18A 0 0.100 -0.380 0.610 0.207

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CCNH Ubiquitylation K189 0.418 _K(gl)TADDFLNR_
CHD8 Phosphorylation S557 -0.452 _VPVHQHS(ph)PSEPFLEKPVPDM(ox)TQVSGPNAQLVK_
CHD8 Ubiquitylation K1766 0.498 _EQMK(gl)IEAAER_
CHD8 Phosphorylation S1874 -0.088 -0.155 _TPFKDEIDEFANS(ph)PSEDKEESMEIHATGK_
CHD8 Phosphorylation S1978 0.606 0.061 _M(ox)NYM(ox)QNHQAGAPAPSLS(ph)R_
CHD8 Phosphorylation T1993 -1.383 -1.407 _T(ph)ASPLPLRPDAPVEKS(ph)PEETATQVPSLESLTLK_
CHD8 Phosphorylation S1995 -0.690 -1.351 _TAS(ph)PLPLRPDAPVEK_
CHD8 Phosphorylation S2008 -1.339 -1.407 _T(ph)ASPLPLRPDAPVEKS(ph)PEETATQVPSLESLTLK_
CHD8 Phosphorylation S2046 0.427 0.449 _VS(ph)PSDTTPLVSR_
CHD8 Phosphorylation S2519 -0.083 -0.552 _APGYPSS(ph)PVTTASGTTLR_
CHD8 Phosphorylation S2533 -0.792 _RTS(ph)LSAEDAEVTK_
CHD8 Phosphorylation S2559 -0.345 -0.513 _NIPS(ph)PGQLDPDTR_
CHD8 Phosphorylation S2956 0.383 -0.248 _DGETLEGS(ph)DAEESLDK_
DDX11 Ubiquitylation K173 0.779 -0.864 _VQLK(gl)YAAK_
DDX11 Ubiquitylation K520 -0.747 _YCEK(gl)SMISR_
DDX11 Ubiquitylation K830 -1.499 _SAELQEK(gl)MAYLDQTLPR_
ERCC2 Ubiquitylation K268 5.973 1.957 _CQGNLETLQK(gl)TVLR_
ERCC2 Ubiquitylation K507 -2.034 _GNDQVAISSK(gl)FETR_
ERCC6 Phosphorylation S158 0.039 0.466 _IIEQLS(ph)PQAATSR_
ERCC6 Phosphorylation S212 -0.295 _IELDHAS(ph)LEEDAEPGPSSLGSMLMPVQETAWEELIR_
ERCC6 Ubiquitylation K255 0.184 -1.007 _TGQMTPFGTQIPQK(gl)QEK_
ERCC6 Ubiquitylation K258 0.830 -1.007 _TGQMTPFGTQIPQKQEK(gl)_
ERCC6 Phosphorylation T303 -1.105 _KAPAPVT(ph)PPAPVQNK_
ERCC6 Ubiquitylation K345 0.454 -0.211 _ALQFQGK(gl)VGLPK_
ERCC6 Ubiquitylation K606 0.305 _VAILHETGSYTHK(gl)K_
ERCC6 Ubiquitylation K607 0.278 _VAILHETGSYTHKK(gl)_
ERCC6 Ubiquitylation K663 -0.597 0.145 _NPNAAVTLACK(gl)QFR_
ERCC6 Ubiquitylation K729 1.490 0.510 _TAYK(gl)CACVLR_
ERCC6 Ubiquitylation K759 -0.019 _MSLSLPDK(gl)NEQVLFCR_
ERCC6 Ubiquitylation K774 0.041 1.536 _LTDEQHK(gl)VYQNFVDSK_
ERCC6 Ubiquitylation K783 0.262 -0.019 _VYQNFVDSK(gl)EVYR_
ERCC6 Ubiquitylation K955 -0.048 -0.623 _K(gl)QVTVYR_
ERCC6 Phosphorylation S1068 0.742 0.512 _KFPASNISVNDATS(ph)SEEKSEAK_
ERCC6 Phosphorylation S1142 0.830 0.891 _TSMPS(ph)GDESIDEK_
ERCC6 Phosphorylation S1146 1.367 0.961 _TSMPSGDES(ph)IDEK_
ERCC6 Ubiquitylation K1156 0.818 -0.034 _LGLSYK(gl)R_
ERCC6 Ubiquitylation K1295 0.149 0.443 _VAQDALK(gl)ALR_
ERCC6 Ubiquitylation K1327 -0.793 0.156 _GISGAPAGK(gl)K_
ERCC6 Ubiquitylation K1328 -0.793 0.232 _GISGAPAGKK(gl)_
ERCC6 Phosphorylation S1345 0.486 0.469 _NSNFSVQHPS(ph)STSPTEK_
ERCC6 Phosphorylation S1346 0.052 0.548 _NSNFSVQHPSS(ph)TSPTEK_
ERCC6 Phosphorylation T1347 0.180 0.745 _NSNFSVQHPSST(ph)SPTEK_
ERCC6 Phosphorylation S1348 0.238 0.374 _NSNFSVQHPSSTS(ph)PTEK_
ERCC6 Ubiquitylation K1352 -1.415 _NSNFSVQHPSSTSPTEK(gl)CQDGIMK_
ERCC6 Ubiquitylation K1359 0.923 _CQDGIMK(gl)K_
ERCC6 Ubiquitylation K1360 2.898 _CQDGIMKK(gl)_
ERCC6 Ubiquitylation K1363 -0.116 -0.707 _EGK(gl)DNVPEHFSGR_
ERCC6 Phosphorylation S1379 0.589 0.418 _AEDADS(ph)SSGPLASSSLLAK_
ERCC6 Ubiquitylation K1392 -0.822 -0.293 _AEDADSSSGPLASSSLLAK(gl)MR_
ERCC6 Ubiquitylation K1457 0.602 1.210 _EILQEFESK(gl)LSASQSCVFR_
ERCC6 Ubiquitylation K1487 -0.363 -0.266 _TSGGEGIWK(gl)LKPEYC_
GTF2H1 Ubiquitylation K240 2.338 _LNTGSK(gl)DLFAECAK_
GTF2H3 Ubiquitylation K28 -0.741 _QALK(gl)ESQFTLSK_
GTF2H3 Ubiquitylation K74 -0.538 _FLYPGK(gl)NGR_
GTF2H3 Ubiquitylation K125 -0.584 -0.425 _SDIK(gl)GQHTETLLAGSLAK_
GTF2H3 Ubiquitylation K152 -0.594 _MNKEVK(gl)DNQEMK_
GTF2H3 Ubiquitylation K300 -1.837 _ISLPPVLKAK(gl)_
MNAT1 Phosphorylation S279 0.003 0.225 _AAS(ph)PQDLAGGYTSSLACHR_
MSH2 Ubiquitylation K212 -0.233 _ECVLPGGETAGDMGK(gl)LR_
MSH2 Ubiquitylation K249 0.461 _K(gl)GEQMNSAVLPEMENQVAVSSLSAVIK_
MSH2 Ubiquitylation K347 2.867 _LVNQWIK(gl)QPLMDK_
MSH2 Ubiquitylation K531 1.040 _VTCKEEK(gl)VLR_
MSH2 Ubiquitylation K555 0.164 _FTNSK(gl)LTSLNEEYTK_
MSH2 Ubiquitylation K635 -0.376 _IILK(gl)ASR_
MSH6 Phosphorylation S41 -0.708 -0.948 _AAAAPGAS(ph)PSPGGDAAWSEAGPGPRPLAR_
MSH6 Phosphorylation S43 0.319 -0.234 _AAAAPGASPS(ph)PGGDAAWSEAGPGPR_
MSH6 Phosphorylation S137 0.203 0.359 _VHVQFFDDS(ph)PTR_
MSH6 Phosphorylation T139 0.209 _VHVQFFDDSPT(ph)R_
MSH6 Phosphorylation S227 -0.199 -0.192 _SEEDNEIES(ph)EEEVQPK_
MSH6 Ubiquitylation K334 0.193 _QATSISSETK(gl)NTLR_
MSH6 Ubiquitylation K476 1.536 0.184 _YSDSLVQK(gl)GYK_
MSH6 Ubiquitylation K519 2.264 0.186 _IITK(gl)GTQTYSVLEGDPSENYSK_
MSH6 Ubiquitylation K728 0.082 -0.280 _SGAIFTK(gl)AYQR_
MSH6 Ubiquitylation K771 -0.582 -1.069 _VDTCHTPFGK(gl)R_
MSH6 Phosphorylation S830 0.130 1.666 _IHNVGS(ph)PLK_
MSH6 Ubiquitylation K852 -0.044 _AIMYEETTYSK(gl)K_
MSH6 Ubiquitylation K853 -0.044 _AIMYEETTYSK(gl)K_
MSH6 Ubiquitylation K896 -0.342 _QVISLQTK(gl)NPEGR_
MSH6 Ubiquitylation K997 -0.863 _NLPEEYELK(gl)STK_
MSH6 Ubiquitylation K1009 -0.817 _YWTK(gl)TIEK_
MSH6 Ubiquitylation K1030 0.394 -0.156 _DVSLK(gl)DCMR_
MSH6 Ubiquitylation K1240 -0.672 _ELAETIK(gl)CR_
MSH6 Ubiquitylation K1291 0.633 _FIK(gl)GACPK_
MSH6 Ubiquitylation K1296 -1.142 _GACPK(gl)SYGFNAAR_
MSH6 Ubiquitylation K1315 -1.738 _LANLPEEVIQK(gl)GHR_
MSH6 Ubiquitylation K1325 -0.190 _EFEK(gl)MNQSLR_
MYO18A Phosphorylation S140 0.894 0.905 _RFS(ph)FSQR_
MYO18A Phosphorylation S728 -0.154 -0.108 _STS(ph)FRQGPEESGLGDGTGPK_
MYO18A Phosphorylation S2020 -0.376 _SLAPDRS(ph)DDEHDPLDNTSRPR_
RAD51 Ubiquitylation K64 -1.228 _KELINIK(gl)GISEAK_
RAD51B Ubiquitylation K71 -0.262 _MQTAYGIK(gl)AQR_
RAD51C Phosphorylation S20 -0.880 -0.922 _DLVSFPLS(ph)PAVR_
RAD51C Ubiquitylation K72 -1.746 -0.333 _ECLTNK(gl)PR_
RAD51C Ubiquitylation K328 -0.364 _LATLYK(gl)SPSQK_
RBBP4 Ubiquitylation K4 0.699 0.574 _(ac)ADK(gl)EAAFDDAVEER_
RBBP4 Ubiquitylation K160 -1.765 _HPSK(gl)PDPSGECNPDLR_
SMARCA1 Phosphorylation T118 -0.873 -0.490 _SPT(ph)SPLNMK_
SMARCA1 Ubiquitylation K862 1.344 _LLTQGFTNWTK(gl)R_
SMARCA2 Phosphorylation S329 -0.314 -0.351 _IS(ph)PIQKPQGLDPVEILQER_
SMARCA2 Ubiquitylation K333 -1.365 _ISPIQK(gl)PQGLDPVEILQER_
SMARCA2 Ubiquitylation K381 0.558 1.360 _ATVELK(gl)ALR_
SMARCA2 Ubiquitylation K413 -0.238 _DTTLETALNSK(gl)AYKR_
SMARCA2 Phosphorylation S1377 -0.887 -1.142 _GRPPAEKLS(ph)PNPPK_
SMARCA4 Ubiquitylation K357 -0.934 _ITPIQK(gl)PR_
SMARCA4 Ubiquitylation K405 0.109 1.148 _ATIELK(gl)ALR_
SMARCA4 Ubiquitylation K437 -0.317 _DTALETALNAK(gl)AYKR_
SMARCA4 Ubiquitylation K455 0.225 _ITEK(gl)LEK_
SMARCA4 Ubiquitylation K496 0.923 _SVTGK(gl)IQK_
SMARCA4 Phosphorylation S677 -0.880 -0.324 _KAENAEGQTPAIGPDGEPLDETSQMS(ph)DLPVK_
SMARCA4 Ubiquitylation K1283 0.125 _ILAAAK(gl)YK_
SMARCA4 Phosphorylation S1413 -0.265 0.515 _EVDYSDS(ph)LTEK_
SMARCA4 Phosphorylation S1486 -0.713 -0.935 _LS(ph)PNPPNLTK_
TOP2A Phosphorylation S4 -0.623 -0.424 _(ac)M(ox)EVS(ph)PLQPVNENM(ox)QVNK_
TOP2A Ubiquitylation K17 -0.250 _(ac)MEVSPLQPVNENMQVNK(gl)IKK_
TOP2A Ubiquitylation K96 0.284 _IFDEILVNAADNK(gl)QR_
TOP2A Ubiquitylation K131 0.553 -0.638 _GIPVVEHK(gl)VEK_
TOP2A Ubiquitylation K386 -2.203 _ENMTLQPK(gl)SFGSTCQLSEK_
TOP2A Ubiquitylation K397 0.214 0.360 _SFGSTCQLSEK(gl)FIK_
TOP2A Ubiquitylation K426 -0.502 _AQVQLNKK(gl)_
TOP2A Ubiquitylation K489 -0.029 0.171 _GK(gl)ILNVR_
TOP2A Ubiquitylation K520 -0.260 _IVGLQYKK(gl)_
TOP2A Ubiquitylation K529 0.862 0.065 _NYEDEDSLK(gl)TLR_
TOP2A Ubiquitylation K614 -0.287 _YYK(gl)GLGTSTSK_
TOP2A Ubiquitylation K622 -0.581 _GLGTSTSK(gl)EAK_
TOP2A Ubiquitylation K632 -0.171 -0.248 _EYFADMK(gl)R_
TOP2A Ubiquitylation K655 -0.091 -0.407 _YSGPEDDAAISLAFSK(gl)K_
TOP2A Ubiquitylation K656 -0.091 -0.441 _YSGPEDDAAISLAFSKK(gl)_
TOP2A Ubiquitylation K723 -1.207 _SIPSMVDGLK(gl)PGQR_
TOP2A Ubiquitylation K1088 0.061 _GYDSDPVK(gl)AWK_
TOP2A Phosphorylation S1142 0.072 0.040 _VPDEEENEES(ph)DNEKETEK_
TOP2A Ubiquitylation K1159 -0.411 -0.659 _EQELDTLK(gl)R_
TOP2A Ubiquitylation K1199 -0.674 -1.759 _EKQDEQVGLPGKGGK(gl)_
TOP2A Phosphorylation S1249 -0.907 -0.546 _TQMAEVLPS(ph)PR_
TOP2A Phosphorylation S1283 0.168 0.028 _NENTEGS(ph)PQEDGVELEGLK_
TOP2A Phosphorylation S1411 0.232 -0.105 _S(ph)VVSDLEADDVK_
TOP2A Phosphorylation S1414 0.884 0.877 _SVVS(ph)DLEADDVK_
TOP2A Phosphorylation S1429 -1.415 -2.977 _GSVPLSS(ph)SPPATHFPDETEITNPVPK_
TOP2A Phosphorylation S1430 -1.317 _GSVPLSSS(ph)PPATHFPDETEITNPVPK_
TOP2A Phosphorylation T1434 -1.348 _GSVPLSSSPPAT(ph)HFPDETEITNPVPK_
TOP2A Phosphorylation S1506 -0.384 _RKPS(ph)TSDDSDSNFEK_
TTF2 Ubiquitylation K755 -0.600 _VQTSIAVCK(gl)LQACAR_
TTF2 Ubiquitylation K871 -0.839 _SALQSYLK(gl)R_
TTF2 Phosphorylation S880 -0.147 _GNQS(ph)GRSPNNPFSR_
TTF2 Phosphorylation S883 0.016 -0.105 _GNQSGRS(ph)PNNPFSR_
TTF2 Ubiquitylation K1109 -0.514 _VGQQK(gl)DVVIHR_
XRCC3 Ubiquitylation K17 -1.225 _IIAAIK(gl)K_
XRCC3 Ubiquitylation K36 -0.644 _EVLHFSGPDLK(gl)R_
XRCC3 Ubiquitylation K72 -0.839 _GSSILTALQLHQQK(gl)ER_


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