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Query: RBBP4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RBBP4 1 1.843 2.110 -1.240 0.533 -0.610 0.648

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RBBP4 Ubiquitylation K4 0.699 0.574 _(ac)ADK(gl)EAAFDDAVEER_
RBBP4 Ubiquitylation K160 -1.765 _HPSK(gl)PDPSGECNPDLR_

Background Information for RBBP4:


Pubmed-RBBP4 »
Uniprot-RBBP4 »
Biogrid-RBBP4 »
ProteomicsDB-RBBP4 »

Tumorportal-RBBP4 »
COSMIC-RBBP4 »
GenomeRNAi-RBBP4 »
Genecards-RBBP4


Protein-protein Interactions for RBBP4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ASF1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2AP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHAF1A Cat. description Hein, Mann, Cell 2015
Category members IP bait EED Cat. description Hein, Mann, Cell 2015
Category members IP bait EZH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MBD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NASP Cat. description Hein, Mann, Cell 2015
Category members IP bait PAPSS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SET Cat. description Hein, Mann, Cell 2015
Category members IP bait ASF1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASF1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM60A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATAD2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATAD2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIN37 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIN9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBD3L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MTA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NASP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBBP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUZ12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF219 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RBBP4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members Histone-bd_RBBP4_N IPR022052 0.49
Category members G-protein_beta_WD-40_rep IPR020472 0.12


Protein complexes (CORUM database) featuring RBBP4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 282 SNF2h-cohesin-NuRD complex Database 6.11
Category members Corum 778 LARC complex (LCR-associated remodeling complex) Database 5.04
Category members Corum 1257 ALL-1 supercomplex Database 4.3
Category members Corum 739 SIN3-ING1b complex II Database 4.24
Category members Corum 659 MeCP1 complex Database 4.17
Category members Corum 685 MeCP1 complex Database 4.17
Category members Corum 714 BRM-SIN3A complex Database 4.02
Category members Corum 62 MeCP1 complex Database 3.53
Category members Corum 713 BRG1-SIN3A complex Database 3.51
Category members Corum 646 HDAC1-associated protein complex Database 3.34
Category members Corum 649 HDAC1-associated core complex cII Database 3.34
Category members Corum 61 Mi2/NuRD complex Database 2.87
Category members Corum 614 NRD complex (Nucleosome remodeling and deacetylation complex) Database 2.26
Category members Corum 650 HDAC2-asscociated core complex Database 2.26
Category members Corum 888 MTA2 complex Database 2.24
Category members Corum 632 Anti-HDAC2 complex Database 2.11
Category members Corum 2721 HCF-1 complex Database 2.08
Category members Corum 3048 mSin3A complex Database 1.84
Category members Corum 691 SIN3-SAP25 complex Database 1.77
Category members Corum 743 SIN3-SAP25 complex Database 1.77
Category members Corum 591 SAP complex (Sin3-associated protein complex) Database 1.75
Category members Corum 1495 PID complex Database 1.68
Category members Corum 886 MTA1 complex Database 1.68
Category members Corum 283 Sin3 complex Database 1.47
Category members Corum 54 SIN3 complex Database 1.47
Category members Corum 732 SIN3 complex Database 1.47
Category members Corum 738 SIN3-ING1b complex I Database 1.47
Category members Corum 100 hNURF complex Database 1.44
Category members Corum 919 hNURF complex Database 1.44
Category members Corum 596 SIN3-HDAC-SAP30-ARID4 complex Database 1.42
Category members Corum 695 SIN3-HDAC-SAP30-ARID4 complex Database 1.42
Category members Corum 698 SIN3-HDAC-SAP30-ARID4 complex Database 1.42
Category members Corum 889 MTA1-HDAC core complex Database 1.41
Category members Corum 592 SAP complex (Sin3-associated protein complex) Database 1.33
Category members Corum 2851 ING2 complex Database 0.74
Category members Corum 696 BRMS1-SIN3-HDAC complex Database 0.66
Category members Corum 105 Polycomb repressive complex 2 (PRC 2) Database 0.57
Category members Corum 995 Polycomb repressive complex 3 (PRC3) Database 0.57
Category members Corum 996 Polycomb repressive complex 2 (PRC2) Database 0.57
Category members Corum 1259 Chromatin assembly complex (CAF-1 complex) Database 0.35
Category members Corum 2234 Chromatin assembly complex (CAF-1 complex) Database 0.35
Category members Corum 974 EED-EZH2 complex Database 0.31
Category members Corum 3149 NK-3-Groucho-HIPK2-SIN3A-RbpA48-HDAC1 complex Database 0.04
Category members Corum 5589 LINC complex, S-phase Database 0.01
Category members Corum 5593 LINC core complex Database 0
Category members Corum 5596 LINC complex, quiescent cells Database 0


Categories featuring RBBP4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members GO Category GO:0006338 chromatin remodeling Database 4.95
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0034080 CENP-A containing nucleosome assembly at centromere Database 4.75
Category members Pathway Pathway_1281 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0 4.19
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members Pathway Pathway_881 PID_TELOMERASE_PATHWAY 0 2.64
Category members GO Category GO:0008094 DNA-dependent ATPase activity Database 2.31
Category members Pathway Pathway_313 REACTOME_MITOTIC_G1_G1_S_PHASES 0 1.45
Category members GO Category GO:0016589 NURF complex Database 1.33
Category members GO Category GO:0016581 NuRD complex Database 1.15
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042393 histone binding Database 0.94
Category members Pathway Pathway_325 PID_E2F_PATHWAY 0 0.62
Category members GO Category GO:0035098 ESC/E(Z) complex Database 0.47
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0016580 Sin3 complex Database 0.35
Category members GO Category GO:0033186 CAF-1 complex Database 0.35
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members Pathway Pathway_406 PID_RB_1PATHWAY 0 0.21
Category members GO Category GO:0042826 histone deacetylase binding Database 0.16
Category members Pathway Pathway_984 PID_HEDGEHOG_GLI_PATHWAY 0 0.1
Category members GO Category GO:0031497 chromatin assembly Database 0.04
Category members Pathway Pathway_869 REACTOME_G0_AND_EARLY_G1 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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