bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: RAD51

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAD51 0 0.692 -1.260 1.920

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAD51 Ubiquitylation K64 -1.228 _KELINIK(gl)GISEAK_

Background Information for RAD51:


Pubmed-RAD51 »
Uniprot-RAD51 »
Biogrid-RAD51 »
ProteomicsDB-RAD51 »

Tumorportal-RAD51 »
COSMIC-RAD51 »
GenomeRNAi-RAD51 »
Genecards-RAD51


Protein-protein Interactions for RAD51
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BUB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C9orf126;SCAI Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC42 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC73 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP152 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTNNBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CXXC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait ELMSAN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait ESPN Cat. description Hein, Mann, Cell 2015
Category members IP bait GBF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GORASP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GPKOW Cat. description Hein, Mann, Cell 2015
Category members IP bait HMG20A Cat. description Hein, Mann, Cell 2015
Category members IP bait HMG2L1;HMGXB4 Cat. description Hein, Mann, Cell 2015
Category members IP bait IGBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF13B Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21A Cat. description Hein, Mann, Cell 2015
Category members IP bait KLHL21 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRP8 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH11 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NHSL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLK Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP3CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PRDX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTEN Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNASEH2A Cat. description Hein, Mann, Cell 2015
Category members IP bait ROCK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RTEL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SIDT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLC33A1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBGCP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait UGGT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS4B Cat. description Hein, Mann, Cell 2015
Category members IP bait DMC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FIGNL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSFY1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEAD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAD51
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members DNA_repair_Rad51/TF_NusA_a-hlx IPR010995 0.23
Category members DNA_recomb/repair_RecA IPR013765 0.04
Category members DNA_recomb/repair_RecA-like IPR016467 0.04
Category members RuvA_2-like IPR010994 0
Category members DNA_recomb/repair_Rad51_C IPR013632 0
Category members Circ_KaiC/RadA IPR014774 0
Category members RecA_monomer-monomer_interface IPR020587 0
Category members RecA_ATP-bd IPR020588 0


Protein complexes (CORUM database) featuring RAD51
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2224 MSH2/6-BLM-p53-RAD51 complex Database 0
Category members Corum 2824 BRCA1-RAD51 complex Database 0
Category members Corum 5400 BRCC complex Database 0
Category members Corum 5683 hRAD51C-hXRCC3 complex Database 0


Categories featuring RAD51
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_338 REACTOME_DNA_REPAIR 0 8.18
Category members Pathway Pathway_875 REACTOME_MEIOSIS 0 6.39
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members GO Category GO:0003684 damaged DNA binding Database 4.54
Category members Pathway Pathway_861 REACTOME_DOUBLE_STRAND_BREAK_REPAIR 0 4.5
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members Pathway Pathway_874 REACTOME_MEIOTIC_RECOMBINATION 0 3.7
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members Pathway Pathway_865 PID_ATR_PATHWAY 0 3.46
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members Pathway Pathway_862 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS 0 3
Category members Pathway Pathway_870 PID_BARD1_PATHWAY 0 2.44
Category members GO Category GO:0000724 double-strand break repair via homologous recombination Database 2.41
Category members GO Category GO:0008094 DNA-dependent ATPase activity Database 2.31
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0000794 condensed nuclear chromosome Database 1.58
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0016605 PML body Database 1.41
Category members GO Category GO:0000793 condensed chromosome Database 1.32
Category members Disease phenotype Hereditary_breast_and_ovarian_cancer_syndrome Hereditary breast and ovarian cancer syndrome Database 1.23
Category members GO Category GO:0000228 nuclear chromosome Database 0.89
Category members GO Category GO:0003690 double-stranded DNA binding Database 0.66
Category members Disease phenotype BREAST_CANCER BREAST CANCER Database 0.62
Category members Pathway Pathway_979 BIOCARTA_ATRBRCA_PATHWAY 0 0.6
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members Pathway Pathway_980 BIOCARTA_ATM_PATHWAY 0 0.46
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0000730 DNA recombinase assembly Database 0.31
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0006268 DNA unwinding involved in DNA replication Database 0.19
Category members Disease phenotype Familial_congenital_mirror_movements Familial congenital mirror movements Database 0.18
Category members Pathway Pathway_649 KEGG_PANCREATIC_CANCER 0 0.15
Category members GO Category GO:0006312 mitotic recombination Database 0.14
Category members Pathway Pathway_343 KEGG_HOMOLOGOUS_RECOMBINATION 0 0.12
Category members Pathway Pathway_200 PID_P73PATHWAY 0 0.11
Category members GO Category GO:0009432 SOS response Database 0.04
Category members GO Category GO:0007126 meiosis Database 0.01
Category members GO Category GO:0010569 regulation of double-strand break repair via homologous recombination Database 0.01
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members GO Category GO:0000800 lateral element Database 0
Category members GO Category GO:0006259 DNA metabolic process Database 0
Category members GO Category GO:0007131 reciprocal meiotic recombination Database 0
Category members GO Category GO:0043142 single-stranded DNA-dependent ATPase activity Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0


.

© Copyright Svejstrup Laboratory 2015