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double-strand break repair via homologous recombination
(GO:0000724)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RPA1 6 0.500 0.350 3.133 3.046 0.303 1.770 2.112
RPA3 3 -0.760 1.900 1.805
RAD50 3 0.350 -0.420 0.165 0.571 0.509 0.691 0.587
RPA2 3 -1.830 3.700 1.524
RPA2 3 -1.830 3.700 2.592
BRCA1 2 0.200 -0.140 0.433 0.018 0.146
TP53BP1 2 -1.490 1.970 -0.161 -0.160 0.174
TP53BP1 2 -1.490 1.970 0.638 0.558
NBN 2 -0.220 -0.170 0.708 0.569 -0.563 0.354
RAD51AP1 2 1.090 -0.930
NABP2 2 -0.740 1.510 2.632 2.887
NABP1 2 2.632 2.887
H2AFX 2 -0.474 -0.395 0.182 0.824 0.499
H2AFX 2
RAD21L1 2 2.113 0.118 0.244 0.668 0.414
PALB2 1 -1.420 3.110
TONSL 1 -1.900 3.540 -0.261 -3.160 0.665 1.051
SMC6 1 2.130 -1.240 0.240 0.345 -0.133 0.388
MRE11A 0 1.600 -0.730 0.145 0.420
MRE11A 0 1.600 -0.730 0.023 0.453 0.150
RAD51 0 -1.260 1.920
YY1 0 -0.370 0.560 0.179 0.557 0.050 -0.096 0.076
RBBP8 0 0.120 0.020
LIG1 0 0.370 -0.580
MCM9 0 -0.370 1.390
PSMD14 0 -0.108 -0.655 0.117 -0.121 -0.010
MCM8 0 -0.350 0.360 0.876 0.344 -0.023 0.237 0.753
MCM8 0 -0.350 0.360
SHFM1 0 -0.650 1.350
SHFM1 0 -0.010 -0.190
INO80 0 1.190 -1.020 0.414 0.682
MMS22L 0 0.598 0.329
ATM 0 0.398 0.474
NSMCE2 0
SPIDR 0 -0.940 1.010
ERCC4 0 1.257
MORF4L1 0 0.290 0.210 -0.402 -0.377
MORF4L1 0 0.290 0.210 0.051 -0.078 0.206
SLX4 0 -1.030 1.150 -0.112 0.152
SLX4 0 0.730 -0.910 -0.112 0.152
RAD54B 0 1.010 -0.510
BLM 0 1.270 -0.830 -0.850 -0.141 0.144 0.151 0.149
BLM 0 1.270 -0.830
SMC5 0 -0.480 0.030 -0.134 0.484 -0.303 0.216
AP5Z1 0

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AP5Z1 Ubiquitylation K1436 -0.622 _ASLLLSK(gl)MR_
ATM Ubiquitylation K307 -0.196 _GAYESTK(gl)WR_
ATM Ubiquitylation K331 -0.126 _GK(gl)YSSGFR_
ATM Ubiquitylation K385 -0.669 _ESSDYSVPCK(gl)R_
ATM Ubiquitylation K1101 -0.548 _LFQDTK(gl)GDSSR_
ATM Ubiquitylation K1109 -1.666 _LLK(gl)ALPLK_
ATM Ubiquitylation K1698 -1.026 _DASYTK(gl)ALK_
ATM Ubiquitylation K1738 -0.137 _SAAVTCLK(gl)NILATK_
ATM Ubiquitylation K2025 -1.497 _SIGEPDSLYGCGGGK(gl)MLQPITR_
BLM Phosphorylation S144 1.234 _KLEFSSS(ph)PDSLSTINDWDDMDDFDTSETSK_
BRCA1 Phosphorylation S123 0.465 0.445 _KENNSPEHLKDEVS(ph)IIQSM(ox)GYR_
BRCA1 Phosphorylation S753 2.662 4.077 _VSNNAEDPKDLMLS(ph)GER_
BRCA1 Phosphorylation S1009 0.733 1.028 _KNLLEENFEEHSM(ox)S(ph)PER_
BRCA1 Phosphorylation S1546 1.821 2.105 _NYPS(ph)QEELIK_
BRCA1 Phosphorylation S1564 3.065 _VVDVEEQQLEES(ph)GPHDLTETSYLPR_
BRCA1 Phosphorylation S1664 1.120 _EKPELTAS(ph)TER_
H2AFX Ubiquitylation K116 -0.071 _ATIAGGGVIPHIHK(gl)SLIGK_
H2AFX Ubiquitylation K120 0.702 0.181 _K(gl)TSATVGPK_
H2AFX Ubiquitylation K121 1.548 0.818 _SLIGK(gl)K(gl)GQQK_
H2AFX Ubiquitylation K122 1.238 -0.400 _SLIGK(gl)K(gl)GQQK_
H2AFX Ubiquitylation K126 1.132 _KGQQK(gl)TV_
H2AFX Ubiquitylation K128 -0.411 0.117 _KTSATVGPK(gl)APSGGKK_
H2AFX Phosphorylation S140 1.817 1.205 _KATQAS(ph)QEY_
LIG1 Phosphorylation S49 0.101 _EWNGVVSES(ph)DSPVK_
LIG1 Phosphorylation S51 0.145 -0.066 _EWNGVVSESDS(ph)PVK_
LIG1 Phosphorylation S66 0.671 0.408 _VLGS(ph)EGEEEDEALSPAK_
LIG1 Phosphorylation S76 -0.083 0.108 _VLGSEGEEEDEALS(ph)PAK_
LIG1 Phosphorylation S88 1.273 _GQKPALDCS(ph)QVSPPRPATSPENNASLSDTSPMDSSPSGIPK_
LIG1 Phosphorylation S141 0.697 0.877 _TIQEVLEEQS(ph)EDEDREAK_
LIG1 Phosphorylation T182 -0.768 -0.709 _EGEDGDQPT(ph)TPPKPLK_
LIG1 Phosphorylation T183 -0.923 -0.825 _EGEDGDQPTT(ph)PPKPLK_
LIG1 Phosphorylation T195 0.021 0.224 _AET(ph)PTESVS(ph)EPEVATK_
LIG1 Phosphorylation T197 0.441 0.125 _AETPT(ph)ESVSEPEVATK_
LIG1 Phosphorylation S199 0.721 _AET(ph)PTES(ph)VSEPEVATK_
LIG1 Phosphorylation S201 -0.213 0.070 _AET(ph)PTESVS(ph)EPEVATK_
MCM8 Phosphorylation S26 -0.380 0.511 _ATPAQTPRS(ph)EDAR_
MCM8 Phosphorylation S131 0.424 0.474 _GLQVDLQS(ph)DGAAAEDIVASEQSLGQK_
MCM8 Ubiquitylation K208 1.456 _VYNYEPLTQLK(gl)NVR_
MCM8 Ubiquitylation K220 -0.271 0.326 _SFDK(gl)NLYR_
MCM8 Ubiquitylation K263 -0.018 _YSLPTK(gl)CPVPVCR_
MCM8 Phosphorylation S326 0.118 0.226 _IAEPS(ph)VCGR_
MCM8 Ubiquitylation K353 -0.534 _SLFSDKQMIK(gl)_
MCM8 Ubiquitylation K409 0.140 -0.445 _VSNVK(gl)SVYK_
MCM8 Ubiquitylation K450 -0.607 _VELLK(gl)ELSR_
MCM8 Ubiquitylation K478 -0.439 _LASALAPSIYEHEDIKK(gl)_
MCM8 Ubiquitylation K536 -0.941 -0.853 _GQYTSGK(gl)GSSAVGLTAYVMKDPETR_
MCM8 Ubiquitylation K549 -0.023 -0.647 _GSSAVGLTAYVMK(gl)DPETR_
MCM8 Ubiquitylation K611 -1.605 _TSIIAAANPVGGHYNKAK(gl)_
MCM8 Ubiquitylation K628 -1.124 -3.224 _TSVLAAANPIESQWNPKK(gl)_
MCM8 Ubiquitylation K746 -0.079 _LAEAHAK(gl)VR_
MCM8 Ubiquitylation K752 -0.885 -0.700 _LSNK(gl)VEAIDVEEAK(gl)R_
MCM8 Ubiquitylation K762 -0.483 -0.551 _VEAIDVEEAK(gl)R_
MCM8 Ubiquitylation K770 -0.963 -0.688 _EALK(gl)QSATDPR_
MCM8 Ubiquitylation K814 -1.087 _GK(gl)TPALK_
MCM8 Ubiquitylation K858 0.042 _ALADDDFLTVTGK(gl)TVR_
MCM9 Ubiquitylation K446 -0.450 _AGLVCK(gl)LNTR_
MCM9 Phosphorylation S915 -0.846 -1.814 _SLAQVEEPAIENVKPPGS(ph)PVAK_
MORF4L1 Ubiquitylation K38 -0.038 _VAIKDK(gl)QVK_
MORF4L1 Ubiquitylation K41 -0.246 _VAIKDKQVK(gl)_
MORF4L1 Ubiquitylation K103 -0.693 _VLK(gl)YVDTNLQK_
MORF4L1 Ubiquitylation K111 -0.321 _YVDTNLQK(gl)QR_
MORF4L1 Ubiquitylation K117 -0.190 _ELQK(gl)ANQEQYAEGK_
MORF4L1 Ubiquitylation K127 -0.098 0.304 _ANQEQYAEGK(gl)MR_
MORF4L1 Ubiquitylation K143 -0.206 _TSGLQQK(gl)NVEVK_
MORF4L1 Ubiquitylation K226 -0.743 -0.526 _QLFYLPAK(gl)K_
MORF4L1 Ubiquitylation K227 -0.779 -0.526 _QLFYLPAKK(gl)_
MORF4L1 Ubiquitylation K240 0.245 _NVDSILEDYANYK(gl)K_
MORF4L1 Ubiquitylation K241 0.245 _NVDSILEDYANYK(gl)K_
MORF4L1 Ubiquitylation K249 -1.051 _GNTDNK(gl)EYAVNEVVAGIK_
MRE11A Ubiquitylation K387 0.442 _FSQK(gl)FVDR_
NABP1 Ubiquitylation K8 -1.168 _(ac)TTETFVK(gl)DIKPGLK_
NABP2 Ubiquitylation K8 -1.168 _(ac)TTETFVK(gl)DIKPGLK_
NBN Phosphorylation T335 -1.121 _T(ph)TTPGPSLSQGVSVDEK_
NBN Phosphorylation S341 3.085 _TTTPGPS(ph)LSQGVSVDEK_
NBN Phosphorylation S343 3.710 3.629 _TTTPGPSLS(ph)QGVSVDEK_
NBN Phosphorylation S397 2.719 1.458 _MLS(ph)QDAPTVK_
NBN Phosphorylation S432 -0.192 -0.395 _IPNYQLS(ph)PTK_
NBN Phosphorylation T434 -0.188 -0.683 _IPNYQLSPT(ph)KLPSINK_
NBN Phosphorylation S615 1.985 4.691 _IS(ph)QENEIGKK_
NSMCE2 Ubiquitylation K183 1.381 _NK(gl)VCGHTYEEDAIVR_
PALB2 Phosphorylation S190 1.462 1.104 _NPARS(ph)PVTEIR_
PALB2 Phosphorylation S387 -1.951 _SLS(ph)LEATS(ph)PLSAEK_
PALB2 Phosphorylation S660 0.033 -0.373 _EGSCIFPEELS(ph)PK_
PSMD14 Ubiquitylation K154 -1.127 0.434 _GK(gl)VVIDAFR_
PSMD14 Ubiquitylation K253 0.194 -0.255 _EMLELAK(gl)NYNK_
PSMD14 Ubiquitylation K257 -0.581 -0.994 _NYNK(gl)AVEEEDKMTPEQLAIK_
RAD21L1 Ubiquitylation K72 0.517 _AK(gl)YLLADCNEAFIK_
RAD21L1 Ubiquitylation K335 -0.110 -0.497 _ELDSK(gl)TIR_
RAD21L1 Ubiquitylation K364 0.738 0.610 _LMMWK(gl)ETGGVEK_
RAD21L1 Ubiquitylation K387 -0.350 _LLK(gl)LFTR_
RAD21L1 Ubiquitylation K573 1.907 _ALAK(gl)TGAESISLLELCR_
RAD50 Ubiquitylation K62 -1.069 _YICTGDFPPGTK(gl)GNTFVHDPK_
RAD50 Phosphorylation S635 2.474 3.050 _LFDVCGS(ph)QDFESDLDR_
RAD50 Ubiquitylation K753 0.394 0.397 _NK(gl)LQNVNR_
RAD50 Ubiquitylation K933 0.397 _FQQEKEELINKK(gl)_
RAD50 Ubiquitylation K1068 0.098 _LEENIDNIK(gl)R_
RAD50 Ubiquitylation K1178 -0.548 _SDADENVSASDK(gl)RR_
RAD50 Ubiquitylation K1285 2.195 _SEYVEK(gl)FYR_
RAD51 Ubiquitylation K64 -1.228 _KELINIK(gl)GISEAK_
RAD51AP1 Phosphorylation S120 1.965 3.112 _ELPTVTTNVQNS(ph)QDKSIEK_
RAD51AP1 Phosphorylation S294 -0.337 0.317 _KPLEIRS(ph)PSAESK_
RAD54B Phosphorylation S14 -0.406 _SAAPSQLQGNS(ph)FK_
RBBP8 Phosphorylation S327 -0.154 0.038 _VSS(ph)PVFGATSSIK_
RPA1 Ubiquitylation K163 2.827 4.085 _AYGASK(gl)TFGK_
RPA1 Ubiquitylation K167 3.009 3.243 _TFGK(gl)AAGPSLSHTSGGTQSK_
RPA1 Ubiquitylation K183 0.925 _AAGPSLSHTSGGTQSK(gl)VVPIASLTPYQSK_
RPA1 Ubiquitylation K263 -1.803 _GTLK(gl)IANK_
RPA1 Ubiquitylation K267 2.751 _IANK(gl)QFTAVK_
RPA1 Ubiquitylation K331 3.112 4.066 _SYEDATK(gl)ITVR_
RPA1 Ubiquitylation K410 2.458 _SLSVLSSSTIIANPDIPEAYK(gl)LR_
RPA1 Ubiquitylation K489 0.465 2.335 _K(gl)VIDQQNGLYR_
RPA1 Ubiquitylation K588 -0.055 _IK(gl)ATVMDVKPVDYR_
RPA1 Ubiquitylation K595 1.201 _ATVMDVK(gl)PVDYR_
RPA2 Ubiquitylation K85 0.693 _HAEK(gl)APTNIVYK_
RPA2 Ubiquitylation K235 1.339 _NQLK(gl)HMSVSSIK_
RPA3 Ubiquitylation K33 0.794 _LEK(gl)IHPTGK_
RPA3 Ubiquitylation K39 1.508 1.875 _IHPTGK(gl)MFILSDGEGK_
SHFM1 Ubiquitylation K66 0.280 _HGYK(gl)METS_
SLX4 Ubiquitylation K354 0.981 _TSHLK(gl)QCAVK_
SLX4 Phosphorylation S467 -0.153 _KKPPVS(ph)PPLLLVQDSETTGR_
SLX4 Phosphorylation S1028 -0.250 _LAPWQAS(ph)PPHPCR_
SLX4 Phosphorylation S1044 -1.068 _FLLGPPQGGS(ph)PR_
SLX4 Phosphorylation S1070 0.448 _GGTSQVGS(ph)PTLLSPAVPSK_
SLX4 Ubiquitylation K1179 0.849 -1.465 _SISSDPLEEK(gl)K_
SLX4 Ubiquitylation K1180 0.849 -1.465 _SISSDPLEEK(gl)K_
SLX4 Phosphorylation S1469 0.326 0.010 _S(ph)PGLLDTTPIR_
SMC5 Ubiquitylation K925 -1.832 _ENISQVK(gl)ER_
SMC6 Ubiquitylation K107 -0.691 _GSSLK(gl)GFVK_
SMC6 Ubiquitylation K157 0.258 -0.355 _LK(gl)SATGSVVSTR_
SMC6 Ubiquitylation K201 0.273 0.873 _QFLQSK(gl)NEGDKYK_
SPIDR Ubiquitylation K346 -0.669 _VLFTK(gl)ETAGYLR_
TONSL Ubiquitylation K336 -1.432 _AAEAYQK(gl)QLR_
TONSL Phosphorylation S719 -0.359 -0.212 _VS(ph)PGQAAPAMARPR_
TP53BP1 Phosphorylation S119 2.253 2.083 _TSS(ph)VLGMSVESAPAVEEEKGEELEQK_
TP53BP1 Phosphorylation S265 0.355 0.274 _SEDM(ox)PFS(ph)PK_
TP53BP1 Phosphorylation S280 -0.705 _EQLS(ph)AQELMESGLQIQKSPEPEVLSTQEDLFDQSNK_
TP53BP1 Phosphorylation S287 -1.294 -1.483 _EQLSAQELMES(ph)GLQIQKSPEPEVLSTQEDLFDQSNK_
TP53BP1 Phosphorylation S294 -1.218 -0.875 _S(ph)PEPEVLSTQEDLFDQSNK_
TP53BP1 Phosphorylation S379 -0.210 _STPFIVPS(ph)SPTEQEGR_
TP53BP1 Phosphorylation S380 -0.036 -0.182 _STPFIVPSS(ph)PTEQEGR_
TP53BP1 Phosphorylation T382 -0.167 _STPFIVPSSPT(ph)EQEGR_
TP53BP1 Phosphorylation S500 0.214 0.591 _NS(ph)PEDLGLSLTGDSCK_
TP53BP1 Phosphorylation S525 -0.547 _LM(ox)LSTSEYSQS(ph)PK_
TP53BP1 Phosphorylation S552 0.102 0.080 _IDEDGENTQIEDTEPMS(ph)PVLNSK_
TP53BP1 Phosphorylation S580 1.645 1.855 _FVPAENDSILMNPAQDGEVQLS(ph)QNDDKTK_
TP53BP1 Phosphorylation S771 0.885 _VDVS(ph)CEPLEGVEK_
TP53BP1 Phosphorylation S831 2.288 2.726 _SGTAETEPVEQDSS(ph)QPSLPLVR_
TP53BP1 Phosphorylation T922 1.634 _EGDIIPPLTGAT(ph)PPLIGHLK_
TP53BP1 Phosphorylation S993 2.280 _LVS(ph)PETEASEESLQFNLEKPATGER_
TP53BP1 Phosphorylation S1028 0.901 0.869 _NGSTAVAESVAS(ph)PQK_
TP53BP1 Phosphorylation T1055 1.132 0.932 _SEDPPT(ph)TPIR_
TP53BP1 Phosphorylation T1056 0.818 0.172 _SEDPPTT(ph)PIR_
TP53BP1 Phosphorylation S1067 3.036 2.786 _GNLLHFPS(ph)SQGEEEKEK_
TP53BP1 Phosphorylation S1068 2.467 3.424 _GNLLHFPSS(ph)QGEEEKEKLEGDHTIR_
TP53BP1 Phosphorylation S1094 -1.038 _QSQQPMKPIS(ph)PVKDPVS(ph)PASQK_
TP53BP1 Phosphorylation S1101 -1.038 _QSQQPMKPIS(ph)PVKDPVS(ph)PASQK_
TP53BP1 Phosphorylation S1113 0.104 0.162 _MVIQGPS(ph)SPQGEAMVTDVLEDQK_
TP53BP1 Phosphorylation S1114 0.438 0.116 _M(ox)VIQGPSS(ph)PQGEAM(ox)VTDVLEDQK_
TP53BP1 Phosphorylation S1317 1.156 1.461 _TSS(ph)GTSLSAMHSSGSSGK_
TP53BP1 Phosphorylation S1362 0.462 0.439 _GGPGKLS(ph)PR_
TP53BP1 Phosphorylation S1426 -0.275 0.340 _ETAVPGPLGIEDIS(ph)PNLSPDDK_
TP53BP1 Phosphorylation S1430 -0.558 -0.362 _ETAVPGPLGIEDISPNLS(ph)PDDK_
TP53BP1 Phosphorylation S1460 -0.626 -0.602 _RS(ph)DSPEIPFQAAAGPSDGLDASSPGNSFVGLR_
TP53BP1 Phosphorylation S1462 -1.029 -0.981 _RSDS(ph)PEIPFQAAAGPSDGLDASSPGNSFVGLR_
TP53BP1 Phosphorylation S1618 -0.090 _AADIS(ph)LDNLVEGK_
TP53BP1 Phosphorylation S1673 -0.238 -0.008 _LITS(ph)EEERS(ph)PAK_
TP53BP1 Phosphorylation S1678 -0.242 -0.396 _LITSEEERS(ph)PAK_
YY1 Phosphorylation S247 0.269 0.058 _DIDHETVVEEQIIGENS(ph)PPDYSEYMTGK_
YY1 Ubiquitylation K301 0.655 0.006 _TIACPHK(gl)GCTK_
YY1 Ubiquitylation K339 0.205 _AFVESSK(gl)LKR_


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