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Query: YY1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
YY1 0 2.314 -0.370 0.560 0.179 0.557 0.050 -0.096 0.076

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
YY1 Phosphorylation S247 0.269 0.058 _DIDHETVVEEQIIGENS(ph)PPDYSEYMTGK_
YY1 Ubiquitylation K301 0.655 0.006 _TIACPHK(gl)GCTK_
YY1 Ubiquitylation K339 0.205 _AFVESSK(gl)LKR_

Background Information for YY1:


Pubmed-YY1 »
Uniprot-YY1 »
Biogrid-YY1 »
ProteomicsDB-YY1 »

Tumorportal-YY1 »
COSMIC-YY1 »
GenomeRNAi-YY1 »
Genecards-YY1


Protein-protein Interactions for YY1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR5 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait F9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ID2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1R3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM150A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRPV5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UCHL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in YY1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92
Category members TF_Yin_yang IPR017114 0


Protein complexes (CORUM database) featuring YY1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 116 Polycomb repressive complex 1 (PRC1, hPRC-H) Database 1.56
Category members Corum 2918 Ku antigen-YY1-alphaMyHC promoter complex Database 0.49
Category members Corum 3045 hs4 enhancer complex (faster migrating complex) Database 0.06
Category members Corum 5502 EED-EZH-YY1 polycomb complex Database 0.04
Category members Corum 2946 YY1-Notch1-RBP-Jkappa complex Database 0
Category members Corum 2947 YY1-Notch1 complex Database 0
Category members Corum 3046 hs4 enhancer complex (slow migrating complex) Database 0
Category members Corum 5331 YY1-MDM2-p53 complex Database 0


Categories featuring YY1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0000724 double-strand break repair via homologous recombination Database 2.41
Category members Pathway Pathway_416 PID_P53_REGULATION_PATHWAY 0 2.29
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0031519 PcG protein complex Database 0.62
Category members Pathway Pathway_325 PID_E2F_PATHWAY 0 0.62
Category members GO Category GO:0006403 RNA localization Database 0.49
Category members GO Category GO:0034644 cellular response to UV Database 0.49
Category members Pathway Pathway_849 PID_NOTCH_PATHWAY 0 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0031011 Ino80 complex Database 0.29
Category members GO Category GO:0000400 four-way junction DNA binding Database 0.2
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0051276 chromosome organization Database 0.1
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_119 PID_HES_HEY_PATHWAY 0 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0010225 response to UV-C Database 0
Category members GO Category GO:0034696 response to prostaglandin F Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048593 camera-type eye morphogenesis Database 0


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