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Query: NSMCE2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NSMCE2 0 1.381

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NSMCE2 Ubiquitylation K183 1.381 _NK(gl)VCGHTYEEDAIVR_

Background Information for NSMCE2:





Protein-protein Interactions for NSMCE2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ILK Cat. description Hein, Mann, Cell 2015
Category members IP bait LCK Cat. description Hein, Mann, Cell 2015
Category members IP bait NIPSNAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM8A Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait TGFBR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TM9SF4 Cat. description Hein, Mann, Cell 2015
Category members IP bait EID3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSMCE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF597 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NSMCE2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_MIZ IPR004181 0.13
Category members Ubox_domain IPR003613 0


Protein complexes (CORUM database) featuring NSMCE2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NSMCE2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0000724 double-strand break repair via homologous recombination Database 2.41
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0016605 PML body Database 1.41
Category members GO Category GO:0000722 telomere maintenance via recombination Database 0.64
Category members GO Category GO:0016925 protein sumoylation Database 0.33
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0000781 chromosome, telomeric region Database 0.16
Category members GO Category GO:0030915 Smc5-Smc6 complex Database 0.15
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0019789 SUMO ligase activity Database 0.05
Category members GO Category GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion Database 0
Category members GO Category GO:0045842 positive regulation of mitotic metaphase/anaphase transition Database 0


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