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BIOCARTA_ATM_PATHWAY
(Pathway_980)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RAD50 3 0.350 -0.420 0.165 0.571 0.509 0.691 0.587
JUN 3 -0.930 0.930 -0.126
BRCA1 2 0.200 -0.140 0.433 0.018 0.146
NBN 2 -0.220 -0.170 0.708 0.569 -0.563 0.354
CHEK1 2 -1.170 1.560
CHEK1 2 -1.170 1.560
CHEK2 2 0.530 0.100
MRE11A 0 1.600 -0.730 0.145 0.420
MRE11A 0 1.600 -0.730 0.023 0.453 0.150
RAD51 0 -1.260 1.920
ABL1 0 0.670 -0.070
RBBP8 0 0.120 0.020
NFKB1 0 0.720 -0.810
GADD45A 0 1.050 -0.170
CDKN1A 0 1.080 -0.750
MDM2 0 -0.210 0.080
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
ATM 0 0.398 0.474
RELA 0 -1.130 1.600 0.793

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ABL1 Phosphorylation S1083 -1.131 -0.857 _GQGESDPLDHEPAVS(ph)PLLPR_
ABL1 Phosphorylation S1134 0.293 _SSS(ph)FREMDGQPER_
ABL1 Phosphorylation S1232 0.821 0.183 _SCS(ph)ASCVPHGAK_
ATM Ubiquitylation K307 -0.196 _GAYESTK(gl)WR_
ATM Ubiquitylation K331 -0.126 _GK(gl)YSSGFR_
ATM Ubiquitylation K385 -0.669 _ESSDYSVPCK(gl)R_
ATM Ubiquitylation K1101 -0.548 _LFQDTK(gl)GDSSR_
ATM Ubiquitylation K1109 -1.666 _LLK(gl)ALPLK_
ATM Ubiquitylation K1698 -1.026 _DASYTK(gl)ALK_
ATM Ubiquitylation K1738 -0.137 _SAAVTCLK(gl)NILATK_
ATM Ubiquitylation K2025 -1.497 _SIGEPDSLYGCGGGK(gl)MLQPITR_
BRCA1 Phosphorylation S123 0.465 0.445 _KENNSPEHLKDEVS(ph)IIQSM(ox)GYR_
BRCA1 Phosphorylation S753 2.662 4.077 _VSNNAEDPKDLMLS(ph)GER_
BRCA1 Phosphorylation S1009 0.733 1.028 _KNLLEENFEEHSM(ox)S(ph)PER_
BRCA1 Phosphorylation S1546 1.821 2.105 _NYPS(ph)QEELIK_
BRCA1 Phosphorylation S1564 3.065 _VVDVEEQQLEES(ph)GPHDLTETSYLPR_
BRCA1 Phosphorylation S1664 1.120 _EKPELTAS(ph)TER_
CDKN1A Ubiquitylation K188 -2.505 -1.077 _QTSMTDFYHSK(gl)R_
CHEK1 Ubiquitylation K53 0.879 _AVDCPENIK(gl)K_
CHEK1 Ubiquitylation K54 0.738 _AVDCPENIKK(gl)_
CHEK1 Phosphorylation S296 -0.098 0.184 _VTS(ph)GGVSESPSGFSK_
CHEK1 Phosphorylation S300 1.091 _VTSGGVS(ph)ESPSGFSK_
CHEK1 Phosphorylation S302 1.750 _VTSGGVSES(ph)PSGFSK_
CHEK1 Phosphorylation S317 1.903 _HIQSNLDFS(ph)PVNSASSEENVK_
CHEK1 Ubiquitylation K399 -0.582 _ETCEK(gl)LGYQWK_
CHEK2 Phosphorylation S260 3.670 3.632 _KFAIGS(ph)AR_
CHEK2 Ubiquitylation K437 -0.826 _TQVSLK(gl)DQITSGK_
GADD45A Ubiquitylation K12 -0.515 0.281 _TLEEFSAGEQK(gl)TER_
GADD45A Ubiquitylation K29 0.092 _VGDALEEVLSK(gl)ALSQR_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MDM2 Phosphorylation S166 0.576 1.068 _AIS(ph)ETEENSDELSGER_
MDM2 Ubiquitylation K334 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K336 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K363 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K364 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K473 0.806 _NK(gl)PCPVCR_
MRE11A Ubiquitylation K387 0.442 _FSQK(gl)FVDR_
NBN Phosphorylation T335 -1.121 _T(ph)TTPGPSLSQGVSVDEK_
NBN Phosphorylation S341 3.085 _TTTPGPS(ph)LSQGVSVDEK_
NBN Phosphorylation S343 3.710 3.629 _TTTPGPSLS(ph)QGVSVDEK_
NBN Phosphorylation S397 2.719 1.458 _MLS(ph)QDAPTVK_
NBN Phosphorylation S432 -0.192 -0.395 _IPNYQLS(ph)PTK_
NBN Phosphorylation T434 -0.188 -0.683 _IPNYQLSPT(ph)KLPSINK_
NBN Phosphorylation S615 1.985 4.691 _IS(ph)QENEIGKK_
NFKB1 Phosphorylation S907 -0.025 0.113 _TTSQAHSLPLS(ph)PASTR_
RAD50 Ubiquitylation K62 -1.069 _YICTGDFPPGTK(gl)GNTFVHDPK_
RAD50 Phosphorylation S635 2.474 3.050 _LFDVCGS(ph)QDFESDLDR_
RAD50 Ubiquitylation K753 0.394 0.397 _NK(gl)LQNVNR_
RAD50 Ubiquitylation K933 0.397 _FQQEKEELINKK(gl)_
RAD50 Ubiquitylation K1068 0.098 _LEENIDNIK(gl)R_
RAD50 Ubiquitylation K1178 -0.548 _SDADENVSASDK(gl)RR_
RAD50 Ubiquitylation K1285 2.195 _SEYVEK(gl)FYR_
RAD51 Ubiquitylation K64 -1.228 _KELINIK(gl)GISEAK_
RBBP8 Phosphorylation S327 -0.154 0.038 _VSS(ph)PVFGATSSIK_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_


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