Results for the Category
regulation of double-strand break repair via homologous recombination
(GO:0010569)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| RPA2 | 3 | -1.830 | 3.700 | 1.524 | ||||
| RPA2 | 3 | -1.830 | 3.700 | 2.592 | ||||
| RAD51AP1 | 2 | 1.090 | -0.930 | |||||
| CHEK1 | 2 | -1.170 | 1.560 | |||||
| CHEK1 | 2 | -1.170 | 1.560 | |||||
| TERF2IP | 1 | 0.500 | -0.780 | -0.491 | 1.304 | 2.217 | -1.505 | -0.760 |
| TERF2IP | 1 | 1.450 | -1.010 | -0.491 | 1.304 | 2.217 | -1.505 | -0.760 |
| TERF2IP | 1 | 1.580 | -0.650 | -0.491 | 1.304 | 2.217 | -1.505 | -0.760 |
| RAD51 | 0 | -1.260 | 1.920 | |||||
| SIRT6 | 0 | 1.100 | -1.060 | |||||
| PPP4C | 0 | -0.050 | 0.050 | 0.322 | ||||
| PPP4R2 | 0 | 0.510 | -0.900 | |||||
| SPIDR | 0 | -0.940 | 1.010 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CHEK1 | Ubiquitylation | K53 | 0.879 | _AVDCPENIK(gl)K_ | |
| CHEK1 | Ubiquitylation | K54 | 0.738 | _AVDCPENIKK(gl)_ | |
| CHEK1 | Phosphorylation | S296 | -0.098 | 0.184 | _VTS(ph)GGVSESPSGFSK_ |
| CHEK1 | Phosphorylation | S300 | 1.091 | _VTSGGVS(ph)ESPSGFSK_ | |
| CHEK1 | Phosphorylation | S302 | 1.750 | _VTSGGVSES(ph)PSGFSK_ | |
| CHEK1 | Phosphorylation | S317 | 1.903 | _HIQSNLDFS(ph)PVNSASSEENVK_ | |
| CHEK1 | Ubiquitylation | K399 | -0.582 | _ETCEK(gl)LGYQWK_ | |
| PPP4C | Ubiquitylation | K26 | -0.494 | -0.192 | _ESEVK(gl)ALCAK(gl)AR_ |
| PPP4C | Ubiquitylation | K31 | -0.607 | 0.349 | _ESEVK(gl)ALCAK(gl)AR_ |
| PPP4C | Ubiquitylation | K133 | -0.603 | _K(gl)YGSVTVWR_ | |
| PPP4R2 | Ubiquitylation | K15 | -0.628 | 0.263 | _LQEALKDFEK(gl)R_ |
| PPP4R2 | Ubiquitylation | K141 | -1.105 | -0.483 | _NVMVVSCVYPSSEK(gl)NNSNSLNR_ |
| PPP4R2 | Phosphorylation | S226 | -0.279 | -0.053 | _NHSDSSTSESEVSSVS(ph)PLK_ |
| RAD51 | Ubiquitylation | K64 | -1.228 | _KELINIK(gl)GISEAK_ | |
| RAD51AP1 | Phosphorylation | S120 | 1.965 | 3.112 | _ELPTVTTNVQNS(ph)QDKSIEK_ |
| RAD51AP1 | Phosphorylation | S294 | -0.337 | 0.317 | _KPLEIRS(ph)PSAESK_ |
| RPA2 | Ubiquitylation | K85 | 0.693 | _HAEK(gl)APTNIVYK_ | |
| RPA2 | Ubiquitylation | K235 | 1.339 | _NQLK(gl)HMSVSSIK_ | |
| SIRT6 | Phosphorylation | S10 | -1.087 | _(ac)SVNYAAGLS(ph)PYADK_ | |
| SIRT6 | Phosphorylation | S303 | 0.071 | 0.092 | _LEPKEES(ph)PTR_ |
| SIRT6 | Phosphorylation | T305 | -0.259 | _LEPKEES(ph)PTR_ | |
| SPIDR | Ubiquitylation | K346 | -0.669 | _VLFTK(gl)ETAGYLR_ | |
| TERF2IP | Phosphorylation | S36 | 0.199 | -0.039 | _DDGSSMSFYVRPS(ph)PAK_ |
| TERF2IP | Phosphorylation | S154 | 0.255 | -0.049 | _S(ph)PSSVTGNALWK_ |
| TERF2IP | Phosphorylation | S156 | 0.369 | 0.179 | _ENARSPS(ph)SVTGNALWK_ |
| TERF2IP | Phosphorylation | S157 | 0.410 | _ENARSPSS(ph)VTGNALWK_ | |
| TERF2IP | Phosphorylation | S203 | -0.351 | -0.260 | _YLLGDAPVS(ph)PSSQK_ |
| TERF2IP | Ubiquitylation | K228 | -0.229 | _KAEEDPEAADSGEPQNK(gl)R_ |
.
© Copyright Svejstrup Laboratory 2015