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Query: PPP4R2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPP4R2 0 -0.697 0.510 -0.900

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPP4R2 Ubiquitylation K15 -0.628 0.263 _LQEALKDFEK(gl)R_
PPP4R2 Phosphorylation S226 -0.279 -0.053 _NHSDSSTSESEVSSVS(ph)PLK_
PPP4R2 Ubiquitylation K141 -1.105 -0.483 _NVMVVSCVYPSSEK(gl)NNSNSLNR_

Background Information for PPP4R2:


Pubmed-PPP4R2 »
Uniprot-PPP4R2 »
Biogrid-PPP4R2 »
ProteomicsDB-PPP4R2 »

Tumorportal-PPP4R2 »
COSMIC-PPP4R2 »
GenomeRNAi-PPP4R2 »
Genecards-PPP4R2


Protein-protein Interactions for PPP4R2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PPP4C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP4R2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMEK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CRAMP1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LCMT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MARCKSL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPME1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP2R4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP4R2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSSC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UXS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF785 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPP4R2
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PPP4R2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1245 Protein phosphatase 4 complex Database 0
Category members Corum 1750 PPP4C-PPP4R2-Gemin3-Gemin4 complex Database 0


Categories featuring PPP4R2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0030674 protein binding, bridging Database 0.25
Category members GO Category GO:0010569 regulation of double-strand break repair via homologous recombination Database 0.01
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0030289 protein phosphatase 4 complex Database 0
Category members GO Category GO:0030362 protein phosphatase type 4 regulator activity Database 0


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