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Query: TTF2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TTF2 0 0.892 -1.140 2.160 -0.431 0.525 0.080

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TTF2 Phosphorylation S883 0.016 -0.105 _GNQSGRS(ph)PNNPFSR_
TTF2 Phosphorylation S880 -0.147 _GNQS(ph)GRSPNNPFSR_
TTF2 Ubiquitylation K1109 -0.514 _VGQQK(gl)DVVIHR_
TTF2 Ubiquitylation K755 -0.600 _VQTSIAVCK(gl)LQACAR_
TTF2 Ubiquitylation K871 -0.839 _SALQSYLK(gl)R_

Background Information for TTF2:


Pubmed-TTF2 »
Uniprot-TTF2 »
Biogrid-TTF2 »
ProteomicsDB-TTF2 »

Tumorportal-TTF2 »
COSMIC-TTF2 »
GenomeRNAi-TTF2 »
Genecards-TTF2


Protein-protein Interactions for TTF2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PSMB5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBWD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CETN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMMD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM131B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAVCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IQCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PEX19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TTF2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SNF2_N IPR000330 3.38
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members Helicase/UvrB_dom IPR006935 0.78
Category members Znf_GRF IPR010666 0


Protein complexes (CORUM database) featuring TTF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TTF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0008094 DNA-dependent ATPase activity Database 2.31
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006369 termination of RNA polymerase II transcription Database 0.87
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0006353 DNA-dependent transcription, termination Database 0.26
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0008023 transcription elongation factor complex Database 0


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