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Query: MYO18A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MYO18A 0 2.616 0.100 -0.380 0.610 0.207

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MYO18A Phosphorylation S140 0.894 0.905 _RFS(ph)FSQR_
MYO18A Phosphorylation S728 -0.154 -0.108 _STS(ph)FRQGPEESGLGDGTGPK_
MYO18A Phosphorylation S2020 -0.376 _SLAPDRS(ph)DDEHDPLDNTSRPR_

Background Information for MYO18A:


Pubmed-MYO18A »
Uniprot-MYO18A »
Biogrid-MYO18A »
ProteomicsDB-MYO18A »

Tumorportal-MYO18A »
COSMIC-MYO18A »
GenomeRNAi-MYO18A »
Genecards-MYO18A


Protein-protein Interactions for MYO18A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIAA1279 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYL12A;MYL12B Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait PLK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TPX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait 1-Sep Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDKL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDRGK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HBZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIMS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOX4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PATL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PYCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RCN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC30A6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPC25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPK3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UQCRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YEATS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YIF1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MYO18A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Myosin_head_motor_dom IPR001609 0.17
Category members PDZ IPR001478 0.15
Category members Regulat_G_prot_signal_superfam IPR016137 0.05
Category members IQ_motif_EF-hand-BS IPR000048 0
Category members Myosin_tail IPR002928 0
Category members Prefoldin IPR009053 0
Category members RecA_monomer-monomer_interface IPR020587 0


Protein complexes (CORUM database) featuring MYO18A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MYO18A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0008094 DNA-dependent ATPase activity Database 2.31
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_265 REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 0 1.42
Category members Pathway Pathway_559 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS 0 1.1
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members GO Category GO:0042641 actomyosin Database 0.9
Category members GO Category GO:0005793 endoplasmic reticulum-Golgi intermediate compartment Database 0.74
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members Pathway Pathway_592 REACTOME_SIGNALING_BY_FGFR1_MUTANTS 0 0.4
Category members GO Category GO:0016459 myosin complex Database 0.38
Category members Pathway Pathway_528 REACTOME_SIGNALING_BY_FGFR_MUTANTS 0 0.37
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0043531 ADP binding Database 0.27
Category members GO Category GO:0003774 motor activity Database 0.2
Category members GO Category GO:0031032 actomyosin structure organization Database 0.15
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0007030 Golgi organization Database 0.13
Category members GO Category GO:0038032 termination of G-protein coupled receptor signaling pathway Database 0.05
Category members GO Category GO:0048194 Golgi vesicle budding Database 0.04
Category members GO Category GO:0006259 DNA metabolic process Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0050714 positive regulation of protein secretion Database 0


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