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response to organic substance
(GO:0010033)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
ANXA5 2 0.630 -0.650 4.216 2.645 -1.786 0.476 0.210
SUPT5H 2 -0.200 -0.640 1.025 -0.578 1.307 -1.339 0.255
MAPK9 1 0.110 -0.490
DGKD 1 -1.930 3.220
PPP2R1A 1 -0.260 -0.200 0.714 0.973
PPP2R1A 1 -0.260 -0.200 -0.003 -0.196 0.057
PPP2R1A 1 -0.260 -0.200 1.697 1.450 -1.553
PPP2R1B 1 1.240 -0.730 1.697 1.450 -1.553
PFN1 1 -0.430 -0.180 0.002 2.497 -0.084 0.348 -0.059
CCND1 1 -1.820 3.470
CLK2 1 2.010 -1.310 0.077 0.840
PDGFA 1 0.190 -0.340 -2.109 1.885
BAD 0 -0.660 1.190
CDH1 0 0.150 0.280 -0.623
XRCC1 0 -0.010 0.060 -0.364 -0.736 -0.059 0.224 0.061
APOB 0 0.130 0.050 -4.359 0.702
TIMP1 0 0.660 -0.830
SQLE 0 -0.560 0.410 -1.509 -0.595
ASAH1 0 -0.300 0.340
TGFB1 0 -0.550 1.050
RPS6KB1 0 0.850 -0.600
PPP2CA 0 0.160 -0.540 0.194 0.044 0.215
PPP2CA 0 0.160 -0.540 0.650 1.189
WNT5A 0
CREB1 0 1.080 -0.800 -1.027
TJP2 0 0.160 0.070 -1.237 -1.460
TJP2 0 0.160 0.070 0.144 0.035 0.024
DUSP1 0 0.290 -0.100
CDKN1A 0 1.080 -0.750
XRCC3 0 0.420 -0.620
CDK4 0 1.930 -0.950
CDK4 0 1.930 -0.950 -0.510 0.013
SOD1 0 1.450 -1.250
PAK1 0 1.190 -0.630
FADS1 0 -0.870 0.300
ACSL1 0 -1.550 2.430 -0.319 0.348 -0.094
ACSL1 0 -1.090 1.870 -0.319 0.348 -0.094
ABCG1 0 -0.770 2.080
DNAAF2 0 0.000 0.100
STAT3 0 0.200 -1.270 0.334
RELA 0 -1.130 1.600 0.793
CALR 0 -1.300 2.220 0.480 0.054
SOX2 0 -0.250 0.870
CHUK 0 -0.480

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ABCG1 Ubiquitylation K446 -1.109 _GK(gl)VCNLVPYLR_
ACSL1 Ubiquitylation K386 -0.432 _IFGQANTTLK(gl)R_
ACSL1 Ubiquitylation K521 -2.563 _GPNVFQGYLK(gl)DPAK_
ANXA5 Ubiquitylation K86 0.870 0.551 _LIVALMK(gl)PSR_
ANXA5 Ubiquitylation K108 1.035 0.395 _GAGTNEK(gl)VLTEIIASR_
ASAH1 Ubiquitylation K461 0.139 _ESLDVYELDAK(gl)QGR_
BAD Phosphorylation S74 -0.904 -0.452 _HS(ph)SYPAGTEDDEGM(ox)GEEPSPFR_
BAD Phosphorylation S75 -0.914 -0.660 _HSS(ph)YPAGTEDDEGMGEEPSPFR_
BAD Phosphorylation S97 0.056 _S(ph)RSAPPNLWAAQR_
BAD Phosphorylation S99 -0.299 0.161 _S(ph)APPNLWAAQR_
BAD Phosphorylation S118 1.277 1.089 _RM(ox)S(ph)DEFVDSFKK_
CALR Ubiquitylation K48 0.703 _SDFGK(gl)FVLSSGK_
CALR Ubiquitylation K153 -0.924 0.619 _GK(gl)NVLINK_
CALR Ubiquitylation K159 -1.004 0.381 _NVLINK(gl)DIR_
CCND1 Ubiquitylation K33 -0.490 _AMLK(gl)AEETCAPSVSYFK_
CCND1 Ubiquitylation K46 -1.016 -0.036 _AEETCAPSVSYFK(gl)CVQK_
CCND1 Ubiquitylation K95 -0.733 -0.137 _FLSLEPVK(gl)K_
CCND1 Ubiquitylation K96 -0.846 -0.155 _FLSLEPVKK(gl)_
CCND1 Ubiquitylation K238 0.245 _VIK(gl)CDPDCLR_
CDK4 Ubiquitylation K142 -0.552 _DLK(gl)PENILVTSGGTVK_
CDK4 Ubiquitylation K211 -0.101 _K(gl)PLFCGNSEADQLGK_
CDK4 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4 Ubiquitylation K297 0.247 0.052 _ALQHSYLHK(gl)DEGNPE_
CDK4 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK4 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK4 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK4 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK4 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK4 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK4 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK4 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDKN1A Ubiquitylation K188 -2.505 -1.077 _QTSMTDFYHSK(gl)R_
CHUK Ubiquitylation K296 -1.637 _GGPVDLTLK(gl)QPR_
CREB1 Phosphorylation S271 -0.979 -1.450 _TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1 Ubiquitylation K333 1.343 _ALK(gl)DLYCHK_
DGKD Phosphorylation S56 0.319 0.732 _KVS(ph)TSGQIR_
DNAAF2 Phosphorylation S240 -1.377 -1.883 _APS(ph)PPEAALQPAPTEPR_
DUSP1 Ubiquitylation K97 -0.523 _SAALDGAK(gl)R_
FADS1 Ubiquitylation K106 0.142 _NK(gl)ELTDEFR_
FADS1 Ubiquitylation K251 1.457 _ILSVELGK(gl)QK_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
PAK1 Phosphorylation S174 -1.439 -0.597 _AVSETPAVPPVS(ph)EDEDDDDDDATPPPVIAPRPEHTK_
PAK1 Phosphorylation T212 0.312 _SVIEPLPVT(ph)PTR_
PAK1 Phosphorylation T219 -0.560 -0.962 _DVAT(ph)SPISPTENNTT(ph)PPDALTR_
PAK1 Phosphorylation S220 -0.916 -0.774 _DVATS(ph)PISPTENNTTPPDALTR_
PAK1 Phosphorylation S223 1.033 0.153 _DVATSPIS(ph)PTENNTTPPDALTR_
PAK1 Phosphorylation T225 -1.278 _DVATSPISPT(ph)ENNTTPPDALTR_
PAK1 Phosphorylation T230 -1.418 -1.502 _DVATSPISPTENNTT(ph)PPDALTR_
PFN1 Ubiquitylation K54 -0.190 0.319 _TFVNITPAEVGVLVGK(gl)DR_
PFN1 Ubiquitylation K70 0.186 0.451 _SSFYVNGLTLGGQK(gl)CSVIR_
PFN1 Ubiquitylation K91 -0.513 -0.205 _TK(gl)STGGAPTFNVTVTK_
PFN1 Ubiquitylation K105 0.309 -0.352 _STGGAPTFNVTVTK(gl)TDK_
PFN1 Ubiquitylation K108 0.414 -0.098 _TDK(gl)TLVLLMGK_
PFN1 Ubiquitylation K126 0.640 0.539 _EGVHGGLINK(gl)K_
PFN1 Ubiquitylation K127 0.582 0.353 _EGVHGGLINKK(gl)_
PPP2CA Ubiquitylation K4 -0.788 -0.378 _(ac)MDDK(gl)AFTK_
PPP2CA Ubiquitylation K4 -0.450 -0.016 _(ac)M(ox)DEK(gl)VFTK_
PPP2CA Ubiquitylation K8 -0.522 _VFTK(gl)ELDQWIEQLNECK_
PPP2CA Ubiquitylation K21 -1.370 _ELDQWVEQLNECK(gl)QLNENQVR_
PPP2CA Ubiquitylation K21 -1.106 _ELDQWIEQLNECK(gl)QLSESQVK_
PPP2CA Ubiquitylation K29 0.211 0.122 _QLSESQVK(gl)SLCEK_
PPP2CA Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CA Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CA Ubiquitylation K41 -0.049 0.003 _EILTK(gl)ESNVQEVR_
PPP2CA Ubiquitylation K74 -0.316 -0.316 _IGGK(gl)SPDTNYLFMGDYVDR_
PPP2R1A Ubiquitylation K34 0.304 _K(gl)LSTIALALGVER_
PPP2R1A Ubiquitylation K107 0.584 0.441 _DK(gl)AVESLR_
PPP2R1A Ubiquitylation K163 0.106 0.149 _VSSAVK(gl)AELR_
PPP2R1A Ubiquitylation K175 -0.351 _ASNAVK(gl)AEIR_
PPP2R1A Ubiquitylation K188 0.395 0.130 _AAASK(gl)LGEFAK_
PPP2R1A Ubiquitylation K255 0.301 0.202 _QAAEDK(gl)SWR_
PPP2R1A Ubiquitylation K266 0.464 0.338 _YMVADK(gl)FTELQK_
PPP2R1A Ubiquitylation K284 -0.575 _FSELQK(gl)AMGPK_
PPP2R1A Ubiquitylation K307 0.224 0.500 _VK(gl)EFCENLSADCR_
PPP2R1A Ubiquitylation K467 0.890 _EAATSNLK(gl)K_
PPP2R1A Ubiquitylation K468 0.890 _EAATSNLK(gl)K_
PPP2R1A Ubiquitylation K542 -0.187 _FNVAK(gl)SLQK_
PPP2R1B Ubiquitylation K175 -0.351 _ASNAVK(gl)AEIR_
PPP2R1B Ubiquitylation K284 -0.575 _FSELQK(gl)AMGPK_
RPS6KB1 Ubiquitylation K99 -0.316 _VLGK(gl)GGYGK_
RPS6KB1 Phosphorylation S447 -0.525 -0.458 _TPVS(ph)PVKFSPGDFWGR_
SOD1 Ubiquitylation K4 -0.329 _(ac)ATK(gl)AVCVLK_
SOD1 Ubiquitylation K10 0.211 0.582 _AVCVLK(gl)GDGPVQGIINFEQK_
SOD1 Ubiquitylation K24 -0.435 -0.086 _GDGPVQGIINFEQK(gl)ESNGPVK_
SOD1 Ubiquitylation K31 -0.109 0.332 _ESNGPVK(gl)VWGSIK_
SOD1 Phosphorylation S99 0.405 _HVGDLGNVTADKDGVADVS(ph)IEDSVISLSGDHCIIGR_
SOD1 Ubiquitylation K123 0.352 0.004 _TLVVHEK(gl)ADDLGK_
SOD1 Ubiquitylation K129 0.143 _ADDLGK(gl)GGNEESTK_
SOD1 Ubiquitylation K137 0.464 0.934 _ADDLGKGGNEESTK(gl)TGNAGSR_
SOX2 Phosphorylation S251 0.157 -0.109 _SEASSS(ph)PPVVTSSSHSR_
SQLE Ubiquitylation K90 -2.393 -1.358 _SPPESENK(gl)EQLEAR_
SQLE Ubiquitylation K157 -0.878 _DLK(gl)EPDR_
SQLE Ubiquitylation K235 -0.829 _K(gl)AAMAEPNAK_
SQLE Ubiquitylation K400 -1.368 _SMPASFLPPSSVKK(gl)_
SQLE Ubiquitylation K556 -0.794 _ALLSSGAVLYK(gl)_
STAT3 Ubiquitylation K177 0.957 _VVENLQDDFDFNYK(gl)TLK_
STAT3 Ubiquitylation K180 1.179 _TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3 Ubiquitylation K244 0.262 _TLTDEELADWK(gl)R_
STAT3 Phosphorylation T714 -0.338 _FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3 Phosphorylation S727 -0.079 0.156 _FICVTPTTCSNTIDLPMS(ph)PR_
SUPT5H Phosphorylation S32 -1.198 _S(ph)AAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPK_
SUPT5H Ubiquitylation K143 0.325 _DQREEELGEYYMK(gl)K_
SUPT5H Ubiquitylation K144 0.325 _DQREEELGEYYMK(gl)K_
SUPT5H Ubiquitylation K231 1.246 _GYIYVEAYK(gl)QTHVK_
SUPT5H Ubiquitylation K274 0.337 1.786 _EVANLK(gl)PK_
SUPT5H Ubiquitylation K323 1.006 _MSLK(gl)DWFAK_
SUPT5H Ubiquitylation K627 0.092 _SFAFLHCK(gl)K_
SUPT5H Ubiquitylation K628 0.092 _SFAFLHCK(gl)K_
SUPT5H Ubiquitylation K650 -0.223 _HLVLAGGSK(gl)PR_
SUPT5H Phosphorylation S666 -0.471 -0.100 _DVTNFTVGGFAPMS(ph)PR_
SUPT5H Phosphorylation S671 -0.479 0.444 _ISS(ph)PMHPSAGGQR_
SUPT5H Ubiquitylation K718 0.094 _ISQGPYK(gl)GYIGVVK_
SUPT5H Phosphorylation T806 0.883 _TPHYGSQT(ph)PLHDGSR_
SUPT5H Ubiquitylation K1017 -0.116 _SVTGGMCSVYLK(gl)DSEK_
SUPT5H Phosphorylation T1036 5.538 _VVSISSEHLEPITPT(ph)K_
SUPT5H Ubiquitylation K1037 -1.487 _VVSISSEHLEPITPTK(gl)NNK_
TGFB1 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TIMP1 Ubiquitylation K70 1.253 -0.548 _MYK(gl)GFQALGDAADIR_
TJP2 Phosphorylation S161 -0.169 -0.024 _VQVAALQAS(ph)PPLDQDDR_
TJP2 Phosphorylation S205 0.118 0.563 _SWEDS(ph)PER_
TJP2 Phosphorylation S275 0.891 0.690 _GRS(ph)IDQDYER_
TJP2 Phosphorylation S297 0.478 0.579 _AYS(ph)PEYR_
TJP2 Phosphorylation S446 0.631 _SFS(ph)PEER_
TJP2 Phosphorylation S471 -0.863 0.159 _ERPS(ph)SREDTPSR_
TJP2 Phosphorylation S472 -0.715 0.193 _ERPSS(ph)REDTPSR_
TJP2 Ubiquitylation K506 -0.355 -0.981 _STGDIAGTVVPETNK(gl)EPR_
TJP2 Ubiquitylation K520 -1.549 _YQEEPPAPQPK(gl)AAPR_
TJP2 Ubiquitylation K800 -0.173 0.403 _DAGSEK(gl)STGVVR_
TJP2 Phosphorylation S992 -0.733 _SSEPVQHEES(ph)IRKPSPEPR_
TJP2 Phosphorylation S997 -1.075 -0.616 _SSEPVQHEESIRKPS(ph)PEPR_
TJP2 Phosphorylation S1017 -1.379 -1.918 _DNS(ph)PPPAFKPEPPK_
TJP2 Ubiquitylation K1047 -0.374 -0.833 _SYEYK(gl)SNPSAVAGNETPGASTK_
TJP2 Phosphorylation S1187 0.856 _GS(ph)YGSDAEEEEYRQQLSEHSK_
TJP2 Phosphorylation S1190 0.754 0.727 _GSYGS(ph)DAEEEEYRQQLSEHSK_
WNT5A Ubiquitylation K268 -0.304 _VGDALK(gl)EK_
XRCC1 Ubiquitylation K143 0.287 0.218 _VK(gl)IVCSQPYSK_
XRCC1 Ubiquitylation K183 0.349 _VTVTK(gl)LGQFR_
XRCC1 Phosphorylation S240 -1.676 _TSPVTASDPAGPSYAAATLQASSAASSAS(ph)PVSR_
XRCC1 Phosphorylation T249 -0.792 -0.550 _AIGST(ph)SKPQESPKGK_
XRCC1 Phosphorylation S255 -1.174 -0.626 _AIGSTSKPQES(ph)PK_
XRCC1 Phosphorylation S280 0.316 0.913 _KTPSKPPAQLS(ph)PSVPK_
XRCC1 Phosphorylation S282 0.731 _KTPSKPPAQLS(ph)PSVPK_
XRCC1 Ubiquitylation K355 0.580 _DK(gl)ALELGAK_
XRCC1 Phosphorylation S460 -1.302 -0.863 _TKPTQAAGPS(ph)SPQKPPT(ph)PEETK_
XRCC1 Phosphorylation S461 -2.007 -4.025 _TKPTQAAGPSS(ph)PQKPPTPEETK_
XRCC1 Phosphorylation T467 -1.175 -1.061 _TKPTQAAGPSS(ph)PQKPPT(ph)PEETK_
XRCC1 Phosphorylation T471 -1.661 _TKPTQAAGPSS(ph)PQKPPT(ph)PEETK_
XRCC1 Phosphorylation S475 -0.043 0.033 _AAS(ph)PVLQEDIDIEGVQSEGQDNGAEDSGDTEDELRR_
XRCC3 Ubiquitylation K17 -1.225 _IIAAIK(gl)K_
XRCC3 Ubiquitylation K36 -0.644 _EVLHFSGPDLK(gl)R_
XRCC3 Ubiquitylation K72 -0.839 _GSSILTALQLHQQK(gl)ER_


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