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Query: ACSL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ACSL1 0 1.933 -1.550 2.430 -0.319 0.348 -0.094
ACSL1 0 1.933 -1.090 1.870 -0.319 0.348 -0.094

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ACSL1 Ubiquitylation K386 -0.432 _IFGQANTTLK(gl)R_
ACSL1 Ubiquitylation K521 -2.563 _GPNVFQGYLK(gl)DPAK_

Background Information for ACSL1:


Pubmed-ACSL1 »
Uniprot-ACSL1 »
Biogrid-ACSL1 »
ProteomicsDB-ACSL1 »

Tumorportal-ACSL1 »
COSMIC-ACSL1 »
GenomeRNAi-ACSL1 »
Genecards-ACSL1


Protein-protein Interactions for ACSL1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in ACSL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members AMP-binding IPR020459 0.04
Category members AMP-dep_Synth/Lig IPR000873 0


Protein complexes (CORUM database) featuring ACSL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ACSL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0044539 long-chain fatty acid import Database 0.53
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_133 KEGG_FATTY_ACID_METABOLISM 0 0.31
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members Pathway Pathway_6 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS 0 0.2
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0035338 long-chain fatty-acyl-CoA biosynthetic process Database 0.1
Category members Pathway Pathway_2 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS 0 0.08
Category members Pathway Pathway_143 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM 0 0.07
Category members GO Category GO:0033559 unsaturated fatty acid metabolic process Database 0.07
Category members GO Category GO:0036109 alpha-linolenic acid metabolic process Database 0.07
Category members GO Category GO:0008610 lipid biosynthetic process Database 0.05
Category members Pathway Pathway_152 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS 0 0.04
Category members GO Category GO:0005778 peroxisomal membrane Database 0.01
Category members Pathway Pathway_153 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE 0 0
Category members Pathway Pathway_25 KEGG_PEROXISOME 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_40 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_43 KEGG_PPAR_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0001676 long-chain fatty acid metabolic process Database 0
Category members GO Category GO:0004467 long-chain fatty acid-CoA ligase activity Database 0
Category members GO Category GO:0006631 fatty acid metabolic process Database 0
Category members GO Category GO:0006641 triglyceride metabolic process Database 0
Category members GO Category GO:0007584 response to nutrient Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0010033 response to organic substance Database 0
Category members GO Category GO:0014070 response to organic cyclic compound Database 0
Category members GO Category GO:0015908 fatty acid transport Database 0
Category members GO Category GO:0016874 ligase activity Database 0
Category members GO Category GO:0019432 triglyceride biosynthetic process Database 0
Category members GO Category GO:0033211 adiponectin-activated signaling pathway Database 0
Category members GO Category GO:0034201 response to oleic acid Database 0
Category members GO Category GO:0042178 xenobiotic catabolic process Database 0
Category members GO Category GO:0043651 linoleic acid metabolic process Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0


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