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REACTOME_TRIGLYCERIDE_BIOSYNTHESIS
(Pathway_2)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
AGPAT4 1 0.080 -0.600 2.654 1.290
ACLY 1 1.120 -0.800
AGPAT9 1 -1.700 2.440
ELOVL5 0 1.610 -1.090 0.744 0.758
ELOVL5 0 1.610 -1.090
ELOVL1 0 -0.180 0.140 0.818 -0.325
ACSL4 0 1.120 -0.740 -0.154 -1.054 0.236 0.117
TECR 0 0.220 -0.260 0.497 0.272
ELOVL4 0 -0.080 -0.230
ACSL3 0 -1.350 2.060 0.010 0.425 -0.116 0.343 0.188
HSD17B12 0 0.180 -0.130 1.013 -0.647
HSD17B12 0 0.180 -0.130 0.799 0.606
ACSL1 0 -1.550 2.430 -0.319 0.348 -0.094
ACSL1 0 -1.090 1.870 -0.319 0.348 -0.094
GPD1L 0 -0.160 0.390 -0.064
LPCAT1 0 0.790 -0.740 0.844 0.107 0.289
AGPAT5 0 1.438 1.344
AGPAT3 0 -1.100 2.450 0.521
ACSL6 0 -1.270 2.480 -0.319 0.348 -0.094
ACSL6 0 -0.630 0.500 -0.319 0.348 -0.094
FASN 0 -0.350 -0.530 -0.550 -0.478 -0.892 -0.134 0.004
LCLAT1 0 -0.520 1.020 0.417 0.518
LPCAT4 0 0.590 -0.440
ACSL5 0 0.430 -0.550 -0.319 0.348 -0.094
GK 0 -1.140 2.020 0.808 0.614
GK 0 -1.140 2.020
AGPAT1 0 0.470 -0.120

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ACLY Ubiquitylation K210 -0.990 _AK(gl)PAMPQGK_
ACLY Ubiquitylation K217 -0.283 -0.673 _AKPAM(ox)PQGK(gl)STTLFSR_
ACSL1 Ubiquitylation K386 -0.432 _IFGQANTTLK(gl)R_
ACSL1 Ubiquitylation K521 -2.563 _GPNVFQGYLK(gl)DPAK_
ACSL3 Ubiquitylation K8 0.466 _(ac)MNNHVSSK(gl)PSTMK_
ACSL3 Ubiquitylation K63 -0.973 -1.522 _AKPVNSK(gl)PDSAYR_
ACSL4 Ubiquitylation K49 -1.745 _AK(gl)PTSDKPGSPYR_
ACSL4 Ubiquitylation K54 -1.457 _AKPTSDK(gl)PGSPYR_
ACSL4 Ubiquitylation K354 0.109 0.988 _IGYSSPLTLSDQSSK(gl)IK_
ACSL4 Ubiquitylation K356 0.153 0.800 _IGYSSPLTLSDQSSKIK(gl)_
ACSL4 Ubiquitylation K500 -1.017 -0.639 _LK(gl)DWQEGGYTINDKPNPR_
ACSL4 Ubiquitylation K621 0.455 0.184 _SDQSYVISFVVPNQK(gl)R_
ACSL4 Ubiquitylation K661 0.291 0.519 _EAANAM(ox)K(gl)LER_
ACSL4 Ubiquitylation K670 -0.058 -0.343 _FEIPIK(gl)VR_
ACSL4 Ubiquitylation K702 0.575 _NHYLK(gl)DIER_
ACSL5 Ubiquitylation K386 -0.432 _IFGQANTTLK(gl)R_
ACSL5 Ubiquitylation K521 -2.563 _GPNVFQGYLK(gl)DPAK_
ACSL6 Ubiquitylation K386 -0.432 _IFGQANTTLK(gl)R_
ACSL6 Ubiquitylation K521 -2.563 _GPNVFQGYLK(gl)DPAK_
AGPAT1 Ubiquitylation K67 0.603 _NVENMK(gl)ILR_
AGPAT1 Ubiquitylation K126 0.480 _CVPIAK(gl)R_
AGPAT1 Ubiquitylation K277 -0.258 0.444 _GGGDYLK(gl)KPGGGG_
AGPAT3 Ubiquitylation K119 0.546 _FGVLGSSK(gl)VLAK_
AGPAT3 Ubiquitylation K209 -0.423 _TK(gl)GFTTAVK_
AGPAT5 Ubiquitylation K150 0.087 _FNEK(gl)EMR_
AGPAT5 Ubiquitylation K183 -0.577 -0.231 _YNPEQTK(gl)VLSASQAFAAQR_
AGPAT5 Ubiquitylation K253 -0.755 _ESPTMTEFLCK(gl)ECPK_
AGPAT9 Phosphorylation S68 0.190 0.787 _NSAS(ph)VGIIQR_
AGPAT9 Ubiquitylation K81 -3.124 -1.361 _DESPMEK(gl)GLSGLR_
AGPAT9 Ubiquitylation K407 4.953 _SAIAIQGGLTELPWDGGLK(gl)R_
ELOVL1 Ubiquitylation K275 -0.280 _ALQQNGAPGIAK(gl)VK_
ELOVL4 Ubiquitylation K35 1.277 _WTWSIADK(gl)R_
ELOVL5 Ubiquitylation K56 -1.150 0.805 _NK(gl)QPFSCR_
ELOVL5 Ubiquitylation K135 1.026 _TAGESDMK(gl)IIR_
FASN Ubiquitylation K41 -0.859 -0.543 _WK(gl)AGLYGLPR_
FASN Phosphorylation S207 0.105 0.507 _LGMLS(ph)PEGTCK_
FASN Ubiquitylation K213 -0.346 -0.011 _LGMLSPEGTCK(gl)AFDTAGNGYCR_
FASN Ubiquitylation K235 -0.149 0.117 _SEGVVAVLLTK(gl)K_
FASN Ubiquitylation K236 -0.149 -0.024 _SEGVVAVLLTKK(gl)_
FASN Ubiquitylation K326 0.372 _QEPLLIGSTK(gl)SNM(ox)GHPEPASGLAALAK_
FASN Ubiquitylation K436 -0.250 _TPEAVQK(gl)LLEQGLR_
FASN Ubiquitylation K528 -0.086 -0.587 _SDEAVK(gl)PFGLK_
FASN Ubiquitylation K673 0.201 0.234 _K(gl)EGVFAK(gl)EVR_
FASN Ubiquitylation K776 -1.050 _GLK(gl)PSCTIIPLMK_
FASN Phosphorylation S974 -1.491 -0.989 _LFDHPES(ph)PTPNPTEPLFLAQAEVYK_
FASN Phosphorylation T976 -1.624 -1.495 _LFDHPESPT(ph)PNPTEPLFLAQAEVYK_
FASN Phosphorylation S1028 0.133 -0.404 _DNWVS(ph)FM(ox)DTMLQMSILGSAK_
FASN Ubiquitylation K1065 -1.459 _QK(gl)LYTLQDK_
FASN Ubiquitylation K1072 0.386 0.144 _LYTLQDK(gl)AQVADVVVSR_
FASN Ubiquitylation K1142 0.056 0.226 _AALQEELQLCK(gl)GLVQALQTK_
FASN Ubiquitylation K1151 0.234 -0.094 _GLVQALQTK(gl)VTQQGLK_
FASN Ubiquitylation K1158 -0.496 -0.468 _VTQQGLK(gl)MVVPGLDGAQIPRDPSQQELPR_
FASN Ubiquitylation K1239 -0.362 _ACLDTAVENMPSLK(gl)MK_
FASN Ubiquitylation K1241 -0.510 -0.579 _ACLDTAVENMPSLKMK(gl)_
FASN Phosphorylation S1411 -0.978 _RPTPQDS(ph)PIFLPVDDTSFR_
FASN Ubiquitylation K1582 -1.228 -2.032 _DIMLATGK(gl)LSPDAIPGK_
FASN Ubiquitylation K1704 -0.247 _VFTTVGSAEK(gl)R_
FASN Ubiquitylation K1847 0.204 _YMAQGK(gl)HIGK_
FASN Ubiquitylation K1866 -1.615 -1.050 _VVVQVLAEEPEAVLK(gl)GAKPK_
FASN Ubiquitylation K1869 -0.967 _VVVQVLAEEPEAVLKGAK(gl)_
FASN Ubiquitylation K1871 -0.926 _GAK(gl)PKLM(ox)SAISK_
FASN Ubiquitylation K1878 0.194 -0.638 _LM(ox)SAISK(gl)TFCPAHK_
FASN Ubiquitylation K1911 -0.329 0.084 _GVQK(gl)LVLTSR_
FASN Ubiquitylation K1927 -0.254 -0.492 _TGYQAK(gl)QVR_
FASN Ubiquitylation K1993 -1.641 _DGLLENQTPEFFQDVCK(gl)PK_
FASN Phosphorylation S2198 -1.105 -1.296 _ADEAS(ph)ELACPT(ph)PK_
FASN Phosphorylation T2204 -0.587 -0.205 _ADEASELACPT(ph)PKEDGLAQQQTQLNLR_
FASN Ubiquitylation K2391 -0.844 -0.267 _VLEALLPLK(gl)GLEER_
FASN Ubiquitylation K2426 -0.591 0.390 _SFYYK(gl)LR_
FASN Ubiquitylation K2438 -0.623 -0.362 _AK(gl)YHGNVM(ox)LLR_
FASN Ubiquitylation K2449 -0.636 0.411 _AK(gl)TGGAYGEDLGADYNLSQVCDGK_
GK Ubiquitylation K5 0.292 -0.041 _(ac)AASK(gl)K(gl)AVLGPLVGAVDQGTSSTR_
GK Ubiquitylation K6 -0.313 -0.041 _K(gl)AVLGPLVGAVDQGTSSTR_
GK Ubiquitylation K86 -0.363 -0.394 _LGQLNIDISNIK(gl)AIGVSNQR_
GK Ubiquitylation K128 -1.684 -0.670 _TQSTVESLSK(gl)R_
GK Ubiquitylation K138 0.005 -1.823 _RIPGNNNFVK(gl)SK_
GK Ubiquitylation K140 -0.938 _SK(gl)TGLPLSTYFSAVK_
GK Ubiquitylation K346 -1.465 _DNLGIIK(gl)TSEEIEK_
GK Ubiquitylation K353 0.116 -0.123 _TSEEIEK(gl)LAK_
HSD17B12 Ubiquitylation K84 -0.151 _SK(gl)DKLDQVSSEIKEK_
HSD17B12 Ubiquitylation K261 -0.499 -0.079 _SAIK(gl)TVGLQSR_
LCLAT1 Ubiquitylation K221 -0.448 _SNAFAEK(gl)NGLQK_
LCLAT1 Ubiquitylation K306 -0.188 _EDLQLWCHK(gl)R_
LPCAT1 Ubiquitylation K191 -1.958 -0.654 _TVEEIK(gl)R_
LPCAT1 Ubiquitylation K221 -2.397 _TCLITFK(gl)PGAFIPGAPVQPVVLR_
LPCAT1 Ubiquitylation K347 -0.307 _GLGLKPEK(gl)_
LPCAT4 Phosphorylation S2 -1.886 _(ac)S(ph)QGSPGDWAPLDPTPGPPASPNPFVHELHLSR_
TECR Ubiquitylation K12 -0.345 _HYEVEILDAK(gl)TR_
TECR Ubiquitylation K224 -0.509 _DLRPAGSK(gl)TR_
TECR Ubiquitylation K291 -0.791 -0.675 _SYLK(gl)EFRDYPPLR_


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