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Query: HSD17B12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HSD17B12 0 2.267 0.180 -0.130 1.013 -0.647
HSD17B12 0 2.267 0.180 -0.130 0.799 0.606

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HSD17B12 Ubiquitylation K261 -0.499 -0.079 _SAIK(gl)TVGLQSR_
HSD17B12 Ubiquitylation K84 -0.151 _SK(gl)DKLDQVSSEIKEK_

Background Information for HSD17B12:


Pubmed-HSD17B12 »
Uniprot-HSD17B12 »
Biogrid-HSD17B12 »
ProteomicsDB-HSD17B12 »

Tumorportal-HSD17B12 »
COSMIC-HSD17B12 »
GenomeRNAi-HSD17B12 »
Genecards-HSD17B12


Protein-protein Interactions for HSD17B12
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in HSD17B12
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DH_sc/Rdtase_SDR IPR002198 0
Category members Glc/ribitol_DH IPR002347 0


Protein complexes (CORUM database) featuring HSD17B12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HSD17B12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0031012 extracellular matrix Database 0.45
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0008201 heparin binding Database 0.27
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members Pathway Pathway_6 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS 0 0.2
Category members Pathway Pathway_144 KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS 0 0.13
Category members GO Category GO:0035338 long-chain fatty-acyl-CoA biosynthetic process Database 0.1
Category members Pathway Pathway_2 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS 0 0.08
Category members Pathway Pathway_152 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS 0 0.04
Category members GO Category GO:0005518 collagen binding Database 0.02
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_89 KEGG_STEROID_HORMONE_BIOSYNTHESIS 0 0
Category members GO Category GO:0001968 fibronectin binding Database 0
Category members GO Category GO:0004303 estradiol 17-beta-dehydrogenase activity Database 0
Category members GO Category GO:0006633 fatty acid biosynthetic process Database 0
Category members GO Category GO:0006703 estrogen biosynthetic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0010811 positive regulation of cell-substrate adhesion Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0019432 triglyceride biosynthetic process Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0


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