Results for the Category
REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE
(Pathway_153)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| CPT2 | 1 | -0.880 | 2.130 | -0.156 | 1.567 | 1.079 | ||
| PRKAG2 | 0 | 1.300 | -0.990 | 0.278 | -0.667 | |||
| PRKAB1 | 0 | 0.640 | -1.180 | |||||
| STK11 | 0 | |||||||
| PRKAA1 | 0 | 0.910 | 0.060 | |||||
| CAB39 | 0 | -0.920 | 0.670 | |||||
| ACSL1 | 0 | -1.550 | 2.430 | -0.319 | 0.348 | -0.094 | ||
| ACSL1 | 0 | -1.090 | 1.870 | -0.319 | 0.348 | -0.094 | ||
| PRKAA2 | 0 | -0.030 | -0.350 | |||||
| PRKAA2 | 0 | -0.030 | -0.350 | |||||
| SLC25A20 | 0 | 0.510 | -0.140 | 0.468 | ||||
| PRKAG1 | 0 | 0.400 | -0.420 | 0.278 | -0.667 | |||
| STRADA | 0 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ACSL1 | Ubiquitylation | K386 | -0.432 | _IFGQANTTLK(gl)R_ | |
| ACSL1 | Ubiquitylation | K521 | -2.563 | _GPNVFQGYLK(gl)DPAK_ | |
| CAB39 | Ubiquitylation | K20 | 0.992 | _NLK(gl)ESMAVLEK_ | |
| CPT2 | Ubiquitylation | K189 | -0.819 | _SDTITFK(gl)R_ | |
| CPT2 | Ubiquitylation | K510 | -0.730 | _TETIRPASVYTK(gl)R_ | |
| PRKAA1 | Ubiquitylation | K271 | -0.536 | _ATIK(gl)DIR_ | |
| PRKAA1 | Ubiquitylation | K396 | -0.419 | _HTLDELNPQK(gl)SK_ | |
| PRKAA1 | Ubiquitylation | K485 | -1.326 | -1.554 | _SIDDEITEAK(gl)SGTATPQR_ |
| PRKAA2 | Ubiquitylation | K271 | -0.536 | _ATIK(gl)DIR_ | |
| PRKAA2 | Phosphorylation | S377 | -0.020 | _MPPLIADS(ph)PK_ | |
| PRKAB1 | Phosphorylation | S108 | -0.357 | 0.129 | _S(ph)HNNFVAILDLPEGEHQYK_ |
| PRKAG1 | Ubiquitylation | K78 | -0.588 | _AAPLWDSK(gl)K_ | |
| PRKAG1 | Ubiquitylation | K79 | -0.588 | _AAPLWDSK(gl)K_ | |
| PRKAG1 | Ubiquitylation | K243 | -0.525 | -0.505 | _VSALPVVDEK(gl)GR_ |
| PRKAG2 | Ubiquitylation | K78 | -0.588 | _AAPLWDSK(gl)K_ | |
| PRKAG2 | Ubiquitylation | K79 | -0.588 | _AAPLWDSK(gl)K_ | |
| PRKAG2 | Ubiquitylation | K243 | -0.525 | -0.505 | _VSALPVVDEK(gl)GR_ |
| STK11 | Phosphorylation | S31 | 0.437 | 0.073 | _IDS(ph)TEVIYQPR_ |
| STK11 | Phosphorylation | T32 | 1.256 | 0.248 | _IDS(ph)TEVIYQPR_ |
| STRADA | Ubiquitylation | K7 | -0.518 | _(ac)SFLVSK(gl)PER_ |
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