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Query: PRKAG2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRKAG2 0 -1.419 1.300 -0.990 0.278 -0.667

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRKAG2 Ubiquitylation K243 -0.525 -0.505 _VSALPVVDEK(gl)GR_
PRKAG2 Ubiquitylation K78 -0.588 _AAPLWDSK(gl)K_
PRKAG2 Ubiquitylation K79 -0.588 _AAPLWDSK(gl)K_

Background Information for PRKAG2:


Pubmed-PRKAG2 »
Uniprot-PRKAG2 »
Biogrid-PRKAG2 »
ProteomicsDB-PRKAG2 »

Tumorportal-PRKAG2 »
COSMIC-PRKAG2 »
GenomeRNAi-PRKAG2 »
Genecards-PRKAG2


Protein-protein Interactions for PRKAG2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DCLRE1C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHKG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRKAG2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CBS_dom IPR000644 0


Protein complexes (CORUM database) featuring PRKAG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRKAG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members Pathway Pathway_123 BIOCARTA_CHREBP2_PATHWAY 0 0.61
Category members GO Category GO:0031588 AMP-activated protein kinase complex Database 0.54
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0043531 ADP binding Database 0.27
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0006112 energy reserve metabolic process Database 0.21
Category members Pathway Pathway_44 KEGG_INSULIN_SIGNALING_PATHWAY 0 0.21
Category members GO Category GO:0008286 insulin receptor signaling pathway Database 0.2
Category members GO Category GO:0016208 AMP binding Database 0.2
Category members Pathway Pathway_1149 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 0 0.19
Category members GO Category GO:0005977 glycogen metabolic process Database 0.08
Category members GO Category GO:0045860 positive regulation of protein kinase activity Database 0.06
Category members Pathway Pathway_1150 REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK 0 0.04
Category members Pathway Pathway_1258 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK 0 0.04
Category members Pathway Pathway_1008 KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM 0 0
Category members Pathway Pathway_153 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE 0 0
Category members Pathway Pathway_155 BIOCARTA_LEPTIN_PATHWAY 0 0
Category members Pathway Pathway_190 REACTOME_SIGNALING_BY_INSULIN_RECEPTOR 0 0
Category members Pathway Pathway_302 REACTOME_PKB_MEDIATED_EVENTS 0 0
Category members Pathway Pathway_303 REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE 0 0
Category members Pathway Pathway_304 REACTOME_PI3K_CASCADE 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_40 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0004862 cAMP-dependent protein kinase inhibitor activity Database 0
Category members GO Category GO:0006110 regulation of glycolysis Database 0
Category members GO Category GO:0006469 negative regulation of protein kinase activity Database 0
Category members GO Category GO:0006633 fatty acid biosynthetic process Database 0
Category members GO Category GO:0006754 ATP biosynthetic process Database 0
Category members GO Category GO:0006853 carnitine shuttle Database 0
Category members GO Category GO:0007050 cell cycle arrest Database 0
Category members GO Category GO:0008603 cAMP-dependent protein kinase regulator activity Database 0
Category members GO Category GO:0008607 phosphorylase kinase regulator activity Database 0
Category members GO Category GO:0010800 positive regulation of peptidyl-threonine phosphorylation Database 0
Category members GO Category GO:0016126 sterol biosynthetic process Database 0
Category members GO Category GO:0019217 regulation of fatty acid metabolic process Database 0
Category members GO Category GO:0030295 protein kinase activator activity Database 0
Category members GO Category GO:0030554 adenyl nucleotide binding Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0042304 regulation of fatty acid biosynthetic process Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0
Category members GO Category GO:0046320 regulation of fatty acid oxidation Database 0
Category members GO Category GO:0046324 regulation of glucose import Database 0
Category members GO Category GO:0050790 regulation of catalytic activity Database 0


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