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positive regulation of protein kinase activity
(GO:0045860)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ALS2 0 -0.780 1.190
MAPK8IP2 0 1.730 -1.220
MAP2K3 0 0.780 -0.600
TAB2 0 -0.030 -0.580
TRAF4 0 -0.140 0.360
PSEN1 0 0.930 -1.110
CDC25B 0 -0.180 0.320
PRKAG2 0 1.300 -0.990 0.278 -0.667
RAPGEF2 0 -0.860 1.560
STK11 0
PIK3CA 0
SDC4 0 1.110 -0.650
FGF13 0 1.100 -1.060
CAB39 0 -0.920 0.670
CENPE 0 -0.217 0.213
IQGAP1 0 -0.420 0.300 0.641 -0.402
IQGAP1 0 -0.420 0.300 1.363 0.406 0.007
TOM1L1 0 -0.380 0.180
JTB 0 0.440 -0.790
CDK5 0 -1.100 1.740 -0.236 1.063 0.312
PRKAG1 0 0.400 -0.420 0.278 -0.667
GAS6 0 0.020 0.220 -1.517 -0.502

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ALS2 Phosphorylation S466 1.095 0.857 _KSSS(ph)LVDIREEETEGGSR_
ALS2 Phosphorylation S492 0.013 0.308 _LSLPGLLSQVS(ph)PR_
ALS2 Phosphorylation S1462 -0.133 -0.364 _S(ph)ESPEPGYVVTSSGLLLPVLLPR_
ALS2 Phosphorylation S1464 -0.535 -0.600 _SES(ph)PEPGYVVTSSGLLLPVLLPR_
CAB39 Ubiquitylation K20 0.992 _NLK(gl)ESMAVLEK_
CDC25B Phosphorylation S117 -0.601 _EAFAQRPS(ph)SAPDLMCLSPDR_
CDC25B Phosphorylation S118 -0.832 _EAFAQRPS(ph)SAPDLMCLSPDR_
CDC25B Phosphorylation S241 -2.288 -1.005 _S(ph)VTPPEEQQEAEEPK_
CDC25B Phosphorylation T243 -1.445 _SVT(ph)PPEEQQEAEEPK_
CDC25B Phosphorylation S261 0.275 _S(ph)KSLCHDEIENLLDSDHR_
CDC25B Phosphorylation S263 0.184 _SKS(ph)LCHDEIENLLDSDHR_
CDK5 Ubiquitylation K56 0.606 0.237 _EICLLK(gl)ELK_
CENPE Ubiquitylation K1706 0.146 _DQLK(gl)ENLR_
CENPE Phosphorylation S2651 0.192 _SKS(ph)LPSPHPVR_
FGF13 Ubiquitylation K57 -0.429 0.063 _AK(gl)CHEIFCCPLK_
FGF13 Phosphorylation S224 0.090 0.488 _VAMYKEPS(ph)LHDLTEFSR_
IQGAP1 Ubiquitylation K953 0.650 _NKEQLSDMMMINK(gl)QK_
IQGAP1 Ubiquitylation K959 0.713 0.074 _GGLK(gl)ALSK_
IQGAP1 Ubiquitylation K1389 0.638 1.119 _TILLNTK(gl)R_
IQGAP1 Ubiquitylation K1442 0.488 _SK(gl)SVKEDSNLTLQEK_
IQGAP1 Phosphorylation S1443 0.392 0.273 _SKS(ph)VKEDSNLTLQEK_
IQGAP1 Ubiquitylation K1445 0.863 _SVK(gl)EDSNLTLQEK_
JTB Ubiquitylation K69 -1.118 _AK(gl)TTPECGPTGYVEK_
JTB Ubiquitylation K82 -0.558 _TTPECGPTGYVEK(gl)ITCSSSK_
JTB Ubiquitylation K94 -0.231 _NEFK(gl)SCR_
MAP2K3 Ubiquitylation K84 0.045 -0.277 _GAYGVVEK(gl)VR_
MAP2K3 Ubiquitylation K232 -1.394 _TMDAGCK(gl)PYMAPER_
MAP2K3 Ubiquitylation K247 0.065 -0.737 _INPELNQK(gl)GYNVK_
MAPK8IP2 Ubiquitylation K674 -0.899 0.671 _DLLGSK(gl)R_
PIK3CA Ubiquitylation K864 0.390 0.588 _NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA Ubiquitylation K868 0.204 0.651 _NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA Ubiquitylation K974 -0.273 _GAQECTK(gl)TREFER_
PRKAG1 Ubiquitylation K78 -0.588 _AAPLWDSK(gl)K_
PRKAG1 Ubiquitylation K79 -0.588 _AAPLWDSK(gl)K_
PRKAG1 Ubiquitylation K243 -0.525 -0.505 _VSALPVVDEK(gl)GR_
PRKAG2 Ubiquitylation K78 -0.588 _AAPLWDSK(gl)K_
PRKAG2 Ubiquitylation K79 -0.588 _AAPLWDSK(gl)K_
PRKAG2 Ubiquitylation K243 -0.525 -0.505 _VSALPVVDEK(gl)GR_
PSEN1 Phosphorylation S313 0.844 _VSKNS(ph)KYNAESTER_
PSEN1 Ubiquitylation K314 0.016 0.414 _NSK(gl)YNAESTER_
PSEN1 Phosphorylation S366 -0.340 0.055 _AAVQELSS(ph)SILAGEDPEER_
PSEN1 Phosphorylation S367 0.005 0.066 _AAVQELSSS(ph)ILAGEDPEER_
RAPGEF2 Phosphorylation S1022 0.043 -0.570 _SETS(ph)PVAPR_
RAPGEF2 Phosphorylation S1080 -0.612 _DLPPFGINS(ph)PQALK_
SDC4 Ubiquitylation K190 -0.979 _K(gl)APTNEFYA_
STK11 Phosphorylation S31 0.437 0.073 _IDS(ph)TEVIYQPR_
STK11 Phosphorylation T32 1.256 0.248 _IDS(ph)TEVIYQPR_
TAB2 Phosphorylation S580 -0.075 _S(ph)NSISQIPSLEEMQQLR_
TAB2 Phosphorylation S582 0.331 _SNS(ph)ISQIPSLEEMQQLR_
TAB2 Ubiquitylation K653 -0.519 -0.200 _SIIK(gl)TPK_
TOM1L1 Ubiquitylation K149 -0.037 _EVYLDLVKK(gl)_
TOM1L1 Ubiquitylation K298 -1.457 _ILEQNK(gl)NQK_
TOM1L1 Ubiquitylation K301 -1.762 -1.457 _NQK(gl)EATNTTSEPSAPSQDLLDLSPSPR_
TOM1L1 Phosphorylation S321 0.265 -0.164 _EATNTTSEPSAPSQDLLDLS(ph)PSPR_
TOM1L1 Phosphorylation S323 -1.219 -1.229 _EATNTTSEPSAPSQDLLDLSPS(ph)PR_
TRAF4 Phosphorylation S426 0.249 _GS(ph)LDESSLGFGYPK_


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