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Query: CENPE

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CENPE 0 0.334 -0.217 0.213

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CENPE Phosphorylation S2651 0.192 _SKS(ph)LPSPHPVR_
CENPE Ubiquitylation K1706 0.146 _DQLK(gl)ENLR_

Background Information for CENPE:


Pubmed-CENPE »
Uniprot-CENPE »
Biogrid-CENPE »
ProteomicsDB-CENPE »

Tumorportal-CENPE »
COSMIC-CENPE »
GenomeRNAi-CENPE »
Genecards-CENPE


Protein-protein Interactions for CENPE
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait LRPPRC Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait BFSP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C22orf41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CENPE
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Signal_recog_particl_SRP54_hlx IPR013822 0
Category members Kinesin_motor_dom IPR001752 0
Category members STAT_TF_coiled-coil IPR015988 0


Protein complexes (CORUM database) featuring CENPE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CENPE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members GO Category GO:0007094 mitotic spindle assembly checkpoint Database 0.68
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members GO Category GO:0000940 condensed chromosome outer kinetochore Database 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members Pathway Pathway_1028 PID_PLK1_PATHWAY 0 0.16
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members GO Category GO:0000778 condensed nuclear chromosome kinetochore Database 0.11
Category members GO Category GO:0045860 positive regulation of protein kinase activity Database 0.06
Category members GO Category GO:0007080 mitotic metaphase plate congression Database 0.04
Category members GO Category GO:0000089 mitotic metaphase Database 0
Category members GO Category GO:0000779 condensed chromosome, centromeric region Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007079 mitotic chromosome movement towards spindle pole Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0043515 kinetochore binding Database 0
Category members GO Category GO:0051233 spindle midzone Database 0
Category members GO Category GO:0051382 kinetochore assembly Database 0


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