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mitotic spindle assembly checkpoint
(GO:0007094)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
TPR 3 -1.680 3.070 0.483 -1.104 0.827 0.514
ANAPC2 3 2.010 -0.680 0.379 0.170 0.854 -0.575 0.408
PLK1 2 3.098 -0.387 0.212 -1.949 -0.610
CDC27 1 0.150 -0.590 0.507 1.052 0.322 0.135
CDC27 1 0.150 -0.590 0.262 0.221 1.276 0.303 0.326
CENPF 1 -1.080 2.380 -0.412 -0.373
BUB1B 1 -1.750 3.130
MAD1L1 0 -0.450 0.270
ANAPC4 0 -0.420 0.010 0.358 0.072 1.078 0.803 0.313
ANAPC5 0 -0.960 1.460 0.841 0.514 0.971 -0.014 0.607
CDC23 0 0.610 -0.790 0.891 0.596 1.094 0.626 0.506
KLHL22 0 1.050 -1.010
TTK 0 1.100 -0.950 -1.137 -0.932
MAD2L2 0 -0.960 1.170
CDC20 0 0.030 0.220 -0.353 -1.700
PSMG2 0 0.410 -0.680 0.108 -0.302
CDC16 0 0.870 -0.580 0.918 0.566 1.010 0.588 0.168
CENPE 0 -0.217 0.213
TERF1 0 -1.080 1.620
ATM 0 0.398 0.474
ANAPC1 0 -0.850 0.260 1.381 0.110 0.394 0.286 0.121
ANAPC1 0 1.310 -0.540 1.381 0.110 0.394 0.286 0.121
BUB3 0 1.300 -0.710 -0.089 0.300 0.601 -0.954 -0.333
MAD2L1 0 -1.020 1.520 0.232
ANAPC10 0 -0.400 0.360 0.059 0.487 0.244 0.100
BUB1 0 -0.530 0.350
BUB1 0 -0.530 0.350
UBE2E1 0 1.580 -0.610 -0.786 -0.414
UBE2C 0 -0.130 -0.650
CDC26 0 -1.480 2.340
ANAPC7 0 1.030 -0.740 0.341 0.386 0.860 0.061 0.071

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ANAPC1 Phosphorylation S355 -0.638 _AHS(ph)PALGVHSFSGVQR_
ANAPC1 Phosphorylation S377 0.168 _FNISSHNQS(ph)PKR_
ANAPC1 Ubiquitylation K379 -0.754 _FNISSHNQSPK(gl)R_
ANAPC1 Phosphorylation S563 -0.071 -0.105 _LLGSLDEVVLLSPVPELRDS(ph)SK_
ANAPC1 Phosphorylation S564 -0.242 -0.324 _LLGSLDEVVLLSPVPELRDSS(ph)K_
ANAPC1 Phosphorylation S686 -0.242 0.398 _NFDFEGS(ph)LSPVIAPK_
ANAPC1 Phosphorylation S688 0.196 0.395 _NFDFEGSLS(ph)PVIAPK_
ANAPC1 Ubiquitylation K985 -1.522 _QDLSK(gl)QACEGNLPK_
ANAPC2 Phosphorylation S218 -0.012 0.026 _LLQS(ph)PLCAGCSSDK_
ANAPC2 Phosphorylation S314 -0.286 0.054 _VFLQDGPARPAS(ph)PEAGNTLR_
ANAPC2 Phosphorylation S534 0.186 1.648 _LLHQFSFS(ph)PER_
ANAPC2 Ubiquitylation K546 -0.496 -0.462 _NVELLK(gl)LR_
ANAPC2 Ubiquitylation K624 2.177 _AALEAYCK(gl)K_
ANAPC2 Ubiquitylation K625 2.177 _AALEAYCK(gl)K_
ANAPC4 Phosphorylation S778 0.350 0.273 _IKEEVLS(ph)ESEAENQQAGAAALAPEIVIK_
ANAPC4 Phosphorylation S780 0.273 0.551 _IKEEVLSES(ph)EAENQQAGAAALAPEIVIK_
ANAPC5 Ubiquitylation K229 -1.320 _NDETK(gl)ALTPASLQK_
ANAPC5 Ubiquitylation K289 -0.793 -0.427 _LILTGAESK(gl)SNGEEGYGR_
ANAPC5 Ubiquitylation K367 -0.667 _SDSYVLLEHSVKK(gl)_
ANAPC5 Ubiquitylation K393 -0.618 _AFAGK(gl)TANK_
ANAPC5 Ubiquitylation K669 -0.312 _AMFLVAK(gl)CQVASAASYDQPK_
ANAPC5 Ubiquitylation K703 -1.139 0.080 _NYFAK(gl)VDCK_
ANAPC7 Ubiquitylation K99 0.288 -0.093 _NAVSK(gl)YTMALQQK_
ANAPC7 Ubiquitylation K108 -0.579 _YTMALQQKK(gl)_
ANAPC7 Ubiquitylation K115 -1.398 _TSK(gl)VRPSTGNSASTPQSQCLPSEIEVK_
ANAPC7 Ubiquitylation K180 0.415 _INMMLANLYK(gl)K_
ANAPC7 Ubiquitylation K193 -1.385 _AGQERPSVTSYK(gl)EVLR_
ANAPC7 Ubiquitylation K264 -0.919 0.045 _AISTICSLEKK(gl)_
ANAPC7 Ubiquitylation K467 -0.352 _TLLDK(gl)ALTQRPDYIK_
ANAPC7 Ubiquitylation K477 -0.424 -0.322 _ALTQRPDYIK(gl)AVVK_
ANAPC7 Ubiquitylation K491 -0.507 _EQK(gl)YEDGIALLR_
ATM Ubiquitylation K307 -0.196 _GAYESTK(gl)WR_
ATM Ubiquitylation K331 -0.126 _GK(gl)YSSGFR_
ATM Ubiquitylation K385 -0.669 _ESSDYSVPCK(gl)R_
ATM Ubiquitylation K1101 -0.548 _LFQDTK(gl)GDSSR_
ATM Ubiquitylation K1109 -1.666 _LLK(gl)ALPLK_
ATM Ubiquitylation K1698 -1.026 _DASYTK(gl)ALK_
ATM Ubiquitylation K1738 -0.137 _SAAVTCLK(gl)NILATK_
ATM Ubiquitylation K2025 -1.497 _SIGEPDSLYGCGGGK(gl)MLQPITR_
BUB1 Ubiquitylation K203 -1.190 _NQGSELSGVISSACDK(gl)ESNMER_
BUB1 Phosphorylation S596 0.682 _S(ph)PGDFTSAAQLASTPFHK_
BUB1 Phosphorylation S655 0.296 0.593 _DGKFS(ph)PIQEK_
BUB1B Ubiquitylation K438 -0.825 _EAELLTSAEK(gl)R_
BUB1B Ubiquitylation K475 -0.386 _TGDQQEETMPTK(gl)ETTK_
BUB1B Phosphorylation S543 -0.522 -0.173 _NKS(ph)PPADPPR_
BUB1B Phosphorylation S670 0.830 0.911 _LS(ph)PIIEDSR_
BUB3 Ubiquitylation K8 -0.663 -1.612 _TGSNEFK(gl)LNQPPEDGISSVK_
BUB3 Ubiquitylation K139 -0.810 -0.259 _TPCNAGTFSQPEK(gl)VYTLSVSGDR_
BUB3 Ubiquitylation K179 0.382 -0.019 _RESSLK(gl)YQTR_
BUB3 Ubiquitylation K191 -0.888 -0.645 _AFPNK(gl)QGYVLSSIEGR_
BUB3 Ubiquitylation K216 -0.270 _VAVEYLDPSPEVQK(gl)K_
BUB3 Ubiquitylation K217 -0.808 -0.573 _VAVEYLDPSPEVQKK(gl)_
BUB3 Ubiquitylation K218 -1.484 _VAVEYLDPSPEVQKKK(gl)_
BUB3 Ubiquitylation K322 -0.687 -0.496 _QVTDAETK(gl)PK_
CDC16 Ubiquitylation K138 -0.264 _GK(gl)IYDALDNR_
CDC16 Ubiquitylation K325 -0.111 _YLSK(gl)ATTLEK_
CDC16 Phosphorylation S560 0.315 0.284 _NIIS(ph)PPWDFREFEVEK_
CDC20 Phosphorylation S41 -2.364 _EAAGPAPS(ph)PMR_
CDC20 Phosphorylation T70 -0.739 -0.822 _VQTT(ph)PSKPGGDR_
CDC20 Ubiquitylation K136 -1.643 -0.774 _LSGK(gl)PQNAPEGYQNR_
CDC20 Ubiquitylation K149 -1.522 -0.046 _LK(gl)VLYSQK_
CDC20 Ubiquitylation K155 -1.662 -1.144 _VLYSQK(gl)ATPGSSR_
CDC20 Ubiquitylation K490 -0.793 -0.202 _ASAAK(gl)SSLIHQGIR_
CDC23 Ubiquitylation K147 0.026 _GQVK(gl)NEALR_
CDC23 Ubiquitylation K453 -0.395 _LNQLVEAK(gl)K_
CDC23 Ubiquitylation K454 0.255 _LNQLVEAKK(gl)_
CDC23 Ubiquitylation K472 -0.551 _MALVK(gl)LAK_
CDC23 Phosphorylation T562 1.416 0.114 _NQGET(ph)PTTEVPAPFFLPASLSANNTPTR_
CDC23 Phosphorylation T564 1.463 _NQGETPT(ph)TEVPAPFFLPASLSANNTPTR_
CDC23 Phosphorylation S588 -0.009 0.032 _RVS(ph)PLNLSSVTP_
CDC26 Phosphorylation S42 0.314 0.626 _EDVEVVGGS(ph)DGEGAIGLSSDPK_
CDC27 Phosphorylation S432 3.398 _GGITQPNINDS(ph)LEITK_
CDC27 Ubiquitylation K726 -0.818 _ASVLFANEKYK(gl)_
CENPE Ubiquitylation K1706 0.146 _DQLK(gl)ENLR_
CENPE Phosphorylation S2651 0.192 _SKS(ph)LPSPHPVR_
CENPF Ubiquitylation K263 0.419 -0.113 _STLQIGK(gl)R_
CENPF Phosphorylation S276 0.013 _RDANSSFFDNSSS(ph)PHLLDQLK_
CENPF Ubiquitylation K293 -0.460 _NK(gl)INELELR_
CENPF Ubiquitylation K326 -0.856 _FQELQLQLEKAK(gl)_
CENPF Ubiquitylation K513 -1.965 _NIK(gl)QCLNQSQNFAEEMK_
CENPF Ubiquitylation K555 -0.739 -0.237 _INQQENSLTLEK(gl)LK_
CENPF Ubiquitylation K606 0.112 _ALLSALELKK(gl)_
CENPF Ubiquitylation K657 -0.600 0.172 _TQQIK(gl)SHEYNER_
CENPF Ubiquitylation K689 -0.011 _NLHNVLDSK(gl)SVEVETQK_
CENPF Ubiquitylation K770 -1.636 -0.056 _SK(gl)DASLVTNEDHQR_
CENPF Ubiquitylation K823 -1.207 -0.686 _LEADQSPK(gl)NSAILQNR_
CENPF Phosphorylation S834 1.282 _VDS(ph)LEFSLESQK_
CENPF Ubiquitylation K1022 -0.770 _SISELSDQYKQEK(gl)_
CENPF Phosphorylation S1255 2.400 _GDLETSNLQDMQS(ph)QEISGLKDCEIDAEEK_
CENPF Phosphorylation S1747 -0.145 _LQLQGLDLS(ph)SR_
CENPF Phosphorylation S1750 -1.171 -0.117 _S(ph)LLGIDTEDAIQGR_
CENPF Phosphorylation T1825 -0.475 _ITETGAVKPTGECSGEQSPDT(ph)NYEPPGEDK_
CENPF Ubiquitylation K2069 -0.699 _GELDTMSKK(gl)_
CENPF Ubiquitylation K2713 0.058 _MTAK(gl)ETELQR_
CENPF Ubiquitylation K2739 -1.524 _TAELQEELSGEK(gl)NR_
CENPF Phosphorylation S2996 -1.047 -1.005 _GS(ph)PLLGPVVPGPS(ph)PIPSVTEK_
CENPF Phosphorylation S3007 -0.910 -2.059 _GS(ph)PLLGPVVPGPS(ph)PIPSVTEK_
CENPF Phosphorylation S3119 -0.975 -0.328 _LALS(ph)PLSLGK_
CENPF Phosphorylation S3150 1.391 1.078 _VAQRS(ph)PVDSGTILR_
CENPF Phosphorylation S3175 1.052 0.884 _SVPVNNLPERS(ph)PTDSPR_
KLHL22 Phosphorylation T605 -0.305 -0.001 _SLLLEPPRGT(ph)PDR_
MAD1L1 Phosphorylation S427 -0.024 0.052 _AILGSYDSELTPAEYS(ph)PQLTR_
MAD1L1 Ubiquitylation K618 0.370 _LK(gl)EVFQTK_
MAD2L1 Ubiquitylation K119 0.070 _EK(gl)SQKAIQDEIR_
MAD2L1 Ubiquitylation K122 -0.610 -0.388 _SQK(gl)AIQDEIR_
MAD2L1 Ubiquitylation K200 -0.343 -1.107 _VNSMVAYK(gl)IPVND_
MAD2L2 Ubiquitylation K44 1.121 _EVYPVGIFQK(gl)R_
PLK1 Ubiquitylation K358 -2.258 _EK(gl)EEPVVR_
PLK1 Ubiquitylation K574 1.656 _LSLLEEYGCCK(gl)ELASR_
PSMG2 Ubiquitylation K149 -0.084 _YLLTPSMQK(gl)SVQNK_
PSMG2 Ubiquitylation K154 0.358 _SVQNK(gl)IK_
PSMG2 Ubiquitylation K156 0.060 _IK(gl)SLNWEEMEK_
PSMG2 Ubiquitylation K165 0.558 _SLNWEEMEK(gl)SR_
PSMG2 Ubiquitylation K188 0.201 _IPGGGITK(gl)TLYDESCSK_
TERF1 Phosphorylation S11 -0.248 -0.254 _(ac)AEDVSSAAPS(ph)PR_
TPR Ubiquitylation K40 -0.506 -0.355 _FLADQQSEIDGLK(gl)GR_
TPR Ubiquitylation K146 -0.069 0.593 _LSQELEYLTEDVK(gl)R_
TPR Ubiquitylation K177 -1.953 _LDELQASDVSVK(gl)YR_
TPR Ubiquitylation K290 -0.496 -0.246 _LSNLYK(gl)SAADDSEAK_
TPR Ubiquitylation K312 0.319 _AVEELHK(gl)LLK_
TPR Ubiquitylation K315 -0.400 _LLK(gl)EAGEANK_
TPR Ubiquitylation K364 0.423 -0.115 _ELENANDLLSATK(gl)R_
TPR Ubiquitylation K366 -0.723 _K(gl)GAILSEEELAAMSPTAAAVAK_
TPR Phosphorylation S379 1.008 0.645 _GAILSEEELAAMS(ph)PTAAAVAK_
TPR Phosphorylation T381 0.606 _GAILSEEELAAMSPT(ph)AAAVAK_
TPR Ubiquitylation K390 -0.363 _IVK(gl)PGMK_
TPR Ubiquitylation K433 -0.890 -0.961 _EVEAK(gl)APILK_
TPR Ubiquitylation K449 0.226 -0.444 _AQK(gl)AVASLSVK_
TPR Ubiquitylation K463 -0.204 0.730 _LEQAMK(gl)EIQR_
TPR Ubiquitylation K474 -0.552 -0.279 _LQEDTDK(gl)ANKQSSVLER_
TPR Ubiquitylation K477 -0.752 -0.279 _LQEDTDKANK(gl)QSSVLER_
TPR Ubiquitylation K494 -0.348 -0.293 _RMEIQVK(gl)DLSQQIR_
TPR Ubiquitylation K575 -1.583 -1.014 _EREEQETTSSK(gl)ITELQLK_
TPR Ubiquitylation K713 -0.471 -0.123 _SQNTK(gl)ISTQLDFASK_
TPR Ubiquitylation K723 -0.427 _ISTQLDFASK(gl)R_
TPR Ubiquitylation K773 -1.379 _GANEK(gl)LAVAEVR_
TPR Ubiquitylation K877 -0.998 0.155 _NLDVQLLDTK(gl)R_
TPR Ubiquitylation K895 -0.147 -0.704 _ELLK(gl)NAQK_
TPR Ubiquitylation K931 -0.202 -0.484 _GQPSNK(gl)EDVDDLVSQLR_
TPR Ubiquitylation K952 0.559 0.228 _QTEEQVNDLK(gl)ER_
TPR Ubiquitylation K1081 -1.092 _IAVEAQNK(gl)YER_
TPR Ubiquitylation K1105 0.414 -0.260 _EQVSK(gl)MASVR_
TPR Ubiquitylation K1144 -1.114 _MLKDEVSK(gl)CVCR_
TPR Phosphorylation S1185 -0.321 -0.495 _EGVQGPLNVS(ph)LSEEGK_
TPR Ubiquitylation K1326 -0.405 _SGMLQAEKK(gl)_
TPR Ubiquitylation K1400 0.630 _SNASLTNNQNLIQSLK(gl)EDLNK_
TPR Ubiquitylation K1429 0.511 _VK(gl)TITQVK_
TPR Ubiquitylation K1491 0.233 _SK(gl)SLESQVENLQK_
TPR Ubiquitylation K1670 -2.992 _GIASTSDPPTANIK(gl)PTPVVSTPSK_
TPR Ubiquitylation K1690 0.188 1.291 _VTAAAMAGNK(gl)STPR_
TPR Phosphorylation S2034 1.700 2.036 _AADS(ph)QNSGEGNTGAAESSFSQEVSR_
TPR Phosphorylation S2037 0.660 _AADSQNS(ph)GEGNTGAAESSFSQEVSR_
TPR Phosphorylation S2048 0.701 _AADSQNSGEGNTGAAESS(ph)FSQEVSR_
TPR Phosphorylation S2050 0.764 1.393 _AADSQNSGEGNTGAAESSFS(ph)QEVSR_
TPR Phosphorylation T2116 -0.625 -2.789 _GLQLT(ph)PGIGGMQQHFFDDEDR_
TPR Phosphorylation S2155 0.926 -2.294 _TDGFAEAIHS(ph)PQVAGVPR_
TTK Phosphorylation S281 0.857 0.604 _VPVNLLNS(ph)PDCDVK_
TTK Phosphorylation S436 -0.403 -0.266 _HTTFEQPVFSVSKQS(ph)PPISTSK_
TTK Phosphorylation S821 -1.037 -0.693 _YVLGQLVGLNS(ph)PNSILK_
UBE2C Phosphorylation S3 -0.676 1.443 _(ac)AS(ph)QNRDPAATSVAAAR_
UBE2C Phosphorylation T11 1.337 _(ac)ASQNRDPAAT(ph)SVAAAR_
UBE2C Ubiquitylation K121 -0.180 _EK(gl)WSALYDVR_
UBE2E1 Ubiquitylation K43 0.668 0.523 _NSK(gl)LLSTSAK_
UBE2E1 Ubiquitylation K50 0.531 _LLSTSAK(gl)R_
UBE2E1 Ubiquitylation K54 -1.325 _IQK(gl)ELADITLDPPPNCSAGPK_


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