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Query: MAD1L1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAD1L1 0 0.668 -0.450 0.270

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAD1L1 Phosphorylation S427 -0.024 0.052 _AILGSYDSELTPAEYS(ph)PQLTR_
MAD1L1 Ubiquitylation K618 0.370 _LK(gl)EVFQTK_

Background Information for MAD1L1:


Pubmed-MAD1L1 »
Uniprot-MAD1L1 »
Biogrid-MAD1L1 »
ProteomicsDB-MAD1L1 »

Tumorportal-MAD1L1 »
COSMIC-MAD1L1 »
GenomeRNAi-MAD1L1 »
Genecards-MAD1L1


Protein-protein Interactions for MAD1L1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APC Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1BP Cat. description Hein, Mann, Cell 2015
Category members IP bait ASB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BAG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BMP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC11A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNAB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTRF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZADH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAD1L1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring MAD1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1814 MAD1L1-MAD2L1 complex Database 0


Categories featuring MAD1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005643 nuclear pore Database 6.58
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_790 REACTOME_CELL_CYCLE_CHECKPOINTS 0 3.89
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members Pathway Pathway_866 KEGG_CELL_CYCLE 0 2.13
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0007094 mitotic spindle assembly checkpoint Database 0.68
Category members GO Category GO:0000090 mitotic anaphase Database 0.47
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0007093 mitotic cell cycle checkpoint Database 0.27
Category members Pathway Pathway_210 PID_CMYB_PATHWAY 0 0.2
Category members GO Category GO:0000089 mitotic metaphase Database 0


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