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Query: CENPF

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CENPF 1 5.978 -1.080 2.380 -0.412 -0.373

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CENPF Phosphorylation S1255 2.400 _GDLETSNLQDMQS(ph)QEISGLKDCEIDAEEK_
CENPF Phosphorylation S834 1.282 _VDS(ph)LEFSLESQK_
CENPF Phosphorylation S3150 1.391 1.078 _VAQRS(ph)PVDSGTILR_
CENPF Phosphorylation S3175 1.052 0.884 _SVPVNNLPERS(ph)PTDSPR_
CENPF Ubiquitylation K657 -0.600 0.172 _TQQIK(gl)SHEYNER_
CENPF Ubiquitylation K606 0.112 _ALLSALELKK(gl)_
CENPF Ubiquitylation K2713 0.058 _MTAK(gl)ETELQR_
CENPF Phosphorylation S276 0.013 _RDANSSFFDNSSS(ph)PHLLDQLK_
CENPF Ubiquitylation K689 -0.011 _NLHNVLDSK(gl)SVEVETQK_
CENPF Ubiquitylation K770 -1.636 -0.056 _SK(gl)DASLVTNEDHQR_
CENPF Ubiquitylation K263 0.419 -0.113 _STLQIGK(gl)R_
CENPF Phosphorylation S1750 -1.171 -0.117 _S(ph)LLGIDTEDAIQGR_
CENPF Phosphorylation S1747 -0.145 _LQLQGLDLS(ph)SR_
CENPF Ubiquitylation K555 -0.739 -0.237 _INQQENSLTLEK(gl)LK_
CENPF Phosphorylation S3119 -0.975 -0.328 _LALS(ph)PLSLGK_
CENPF Ubiquitylation K293 -0.460 _NK(gl)INELELR_
CENPF Phosphorylation T1825 -0.475 _ITETGAVKPTGECSGEQSPDT(ph)NYEPPGEDK_
CENPF Ubiquitylation K823 -1.207 -0.686 _LEADQSPK(gl)NSAILQNR_
CENPF Ubiquitylation K326 -0.856 _FQELQLQLEKAK(gl)_
CENPF Phosphorylation S2996 -1.047 -1.005 _GS(ph)PLLGPVVPGPS(ph)PIPSVTEK_
CENPF Ubiquitylation K513 -1.965 _NIK(gl)QCLNQSQNFAEEMK_
CENPF Phosphorylation S3007 -0.910 -2.059 _GS(ph)PLLGPVVPGPS(ph)PIPSVTEK_
CENPF Ubiquitylation K1022 -0.770 _SISELSDQYKQEK(gl)_
CENPF Ubiquitylation K2069 -0.699 _GELDTMSKK(gl)_
CENPF Ubiquitylation K2739 -1.524 _TAELQEELSGEK(gl)NR_

Background Information for CENPF:





Protein-protein Interactions for CENPF

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPF Cat. description Hein, Mann, Cell 2015
Category members IP bait G3BP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLF1IP Cat. description Hein, Mann, Cell 2015
Category members IP bait MYC Cat. description Hein, Mann, Cell 2015
Category members IP bait MZT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NFKBIA Cat. description Hein, Mann, Cell 2015
Category members IP bait PAFAH1B1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM5 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLH Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPAST Cat. description Hein, Mann, Cell 2015
Category members IP bait TP53BP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C4orf43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC68 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ESAM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM167A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FNTB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GOPC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKBKG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAP7D2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF166 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCP10L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WASF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CENPF

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CENPF

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CENPF

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0000785 chromatin Database 2.59
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_968 PID_FOXM1_PATHWAY 0 0.8
Category members GO Category GO:0007094 mitotic spindle assembly checkpoint Database 0.68
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0045120 pronucleus Database 0.27
Category members GO Category GO:0000940 condensed chromosome outer kinetochore Database 0.18
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0045502 dynein binding Database 0.04
Category members GO Category GO:0000085 mitotic G2 phase Database 0
Category members GO Category GO:0000087 mitotic M phase Database 0
Category members GO Category GO:0007517 muscle organ development Database 0
Category members GO Category GO:0010389 regulation of G2/M transition of mitotic cell cycle Database 0
Category members GO Category GO:0016202 regulation of striated muscle tissue development Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0051310 metaphase plate congression Database 0
Category members GO Category GO:0051382 kinetochore assembly Database 0


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