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Query: TOM1L1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TOM1L1 0 -1.214 -0.380 0.180

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TOM1L1 Phosphorylation S321 0.265 -0.164 _EATNTTSEPSAPSQDLLDLS(ph)PSPR_
TOM1L1 Phosphorylation S323 -1.219 -1.229 _EATNTTSEPSAPSQDLLDLSPS(ph)PR_
TOM1L1 Ubiquitylation K298 -1.457 _ILEQNK(gl)NQK_
TOM1L1 Ubiquitylation K301 -1.762 -1.457 _NQK(gl)EATNTTSEPSAPSQDLLDLSPSPR_
TOM1L1 Ubiquitylation K149 -0.037 _EVYLDLVKK(gl)_

Background Information for TOM1L1:


Pubmed-TOM1L1 »
Uniprot-TOM1L1 »
Biogrid-TOM1L1 »
ProteomicsDB-TOM1L1 »

Tumorportal-TOM1L1 »
COSMIC-TOM1L1 »
GenomeRNAi-TOM1L1 »
Genecards-TOM1L1


Protein-protein Interactions for TOM1L1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AGPAT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAV3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MANSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TOM1L1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ENTH_VHS IPR008942 0.96
Category members TOM1 IPR014645 0.53
Category members VHS IPR002014 0
Category members GAT IPR004152 0
Category members VHS_subgr IPR018205 0


Protein complexes (CORUM database) featuring TOM1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TOM1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Database 0.09
Category members GO Category GO:0045839 negative regulation of mitosis Database 0.08
Category members GO Category GO:0045860 positive regulation of protein kinase activity Database 0.06
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0005795 Golgi stack Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0030276 clathrin binding Database 0
Category members GO Category GO:0030295 protein kinase activator activity Database 0
Category members GO Category GO:0031954 positive regulation of protein autophosphorylation Database 0
Category members GO Category GO:0032147 activation of protein kinase activity Database 0


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