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Query: MAPK8IP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAPK8IP2 0 -0.227 1.730 -1.220

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAPK8IP2 Ubiquitylation K674 -0.899 0.671 _DLLGSK(gl)R_

Background Information for MAPK8IP2:


Pubmed-MAPK8IP2 »
Uniprot-MAPK8IP2 »
Biogrid-MAPK8IP2 »
ProteomicsDB-MAPK8IP2 »

Tumorportal-MAPK8IP2 »
COSMIC-MAPK8IP2 »
GenomeRNAi-MAPK8IP2 »
Genecards-MAPK8IP2


Protein-protein Interactions for MAPK8IP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAPK8IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK8IP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAPGEF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAPK8IP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SH3_domain IPR001452 0
Category members PTB/PI_dom IPR006020 0


Protein complexes (CORUM database) featuring MAPK8IP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAPK8IP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0043234 protein complex Database 2.73
Category members Pathway Pathway_309 ST_INTEGRIN_SIGNALING_PATHWAY 0 1.35
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members Pathway Pathway_608 SIG_CD40PATHWAYMAP 0 0.89
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0048813 dendrite morphogenesis Database 0.23
Category members GO Category GO:0046328 regulation of JNK cascade Database 0.22
Category members GO Category GO:0045860 positive regulation of protein kinase activity Database 0.06
Category members GO Category GO:0019894 kinesin binding Database 0.02
Category members Pathway Pathway_386 ST_FAS_SIGNALING_PATHWAY 0 0.02
Category members Pathway Pathway_517 ST_GRANULE_CELL_SURVIVAL_PATHWAY 0 0.02
Category members GO Category GO:0007617 mating behavior Database 0.01
Category members Pathway Pathway_445 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000165 MAPK cascade Database 0
Category members GO Category GO:0001540 beta-amyloid binding Database 0
Category members GO Category GO:0001662 behavioral fear response Database 0
Category members GO Category GO:0005078 MAP-kinase scaffold activity Database 0
Category members GO Category GO:0007172 signal complex assembly Database 0
Category members GO Category GO:0007254 JNK cascade Database 0
Category members GO Category GO:0010469 regulation of receptor activity Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0
Category members GO Category GO:0030295 protein kinase activator activity Database 0
Category members GO Category GO:0032874 positive regulation of stress-activated MAPK cascade Database 0
Category members GO Category GO:0035176 social behavior Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0051966 regulation of synaptic transmission, glutamatergic Database 0
Category members GO Category GO:0060079 regulation of excitatory postsynaptic membrane potential Database 0


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